Population pharmacokinetics of gentamicin in South African newborns

European Journal of Clinical Pharmacology

Volumn 59, Issue 10, 2003, Pages 755-759

  Botha, J H ^a   Du Preez, M J ^a   Adhikari, M ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

Gentamicin; Newborn; Pharmacokinetics

Indexed keywords

GENTAMICIN; TETRACYCLINE;

ARTICLE; COMPARTMENT MODEL; DRUG CLEARANCE; DRUG DISTRIBUTION; FEMALE; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; NEWBORN; NONLINEAR SYSTEM; PRIORITY JOURNAL; SOUTH AFRICA;

ANTI-BACTERIAL AGENTS; BODY WEIGHT; FEMALE; GENTAMICINS; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MALE; METABOLIC CLEARANCE RATE; NONLINEAR DYNAMICS; SEX FACTORS; SOUTH AFRICA;

EID: 0347991799     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-003-0663-6     Document Type: Article

References (17)

1. Assael BM, Rusconi F (1992) Aminoglycoside antibiotics. In: Yaffe SJ, Aranda JV (eds) Pediatric pharmacology: therapeutic principles in practice, 2nd edn. Saunders Company, Philadelphia, pp 244-249
2. Grasela TH, Ott R, Faix RG (1985) Population pharmacokinetics of gentamicin in neonates using routine clinical data. Clin Pharmacol Ther 37:199
3. Kelman AW, Thomson AH, Whiting B, Bryson SM, Steedman DA, Mawer GE, Samba-Donga LA (1984) Estimation of gentamicin clearance and volume of distribution in neonates and young children. Br J Clin Pharmacol 18:685-692
4. Thomson AH, Way S, Bryson SM, McGovern EM, Kelman AW, Whiting B (1988) Population pharmacokinetics of gentamicin in neonates. Dev Pharmacol Ther 11:173-179
5. Jensen PD, Edgren BE, Brundage RC (1992) Population pharmacokinetics of gentamicin in neonates using a nonlinear, mixed-effects model. Pharmacotherapy 12:178-182
6. Weber W, Kewitz G, Rost KL, Looby M, Nitz M, Harnisch L (1993) Population kinetics of gentamicin in neonates. Eur J Clin Pharmacol 44[Suppl 1]:S23-S25
7. Fattinger K, Vozeh S, Olafsson A, Vicek J, Wenk M, Follath F (1991) Netilmicin in the neonate. Population pharmacokinetic analysis and dosing recommendations. Clin Pharmacol Ther 50:55-65
8. de Hoog M, Schoemaker RC, Mouton JW, van den Anker JN (1997) Tobramycin population pharmacokinetics in neonates. Clin Pharmacol Ther 62:392-399
9. Botha JH, du Preez MJ, Miller R, Adhikari M (1998) Determination of population pharmacokinetic parameters for amikacin in neonates using mixed-effect models. Eur J Clin Pharmacol 53:337-341
10. Falcao AC, Buelga DS, Mendez ME, Garcia MJ, Pardo M (2001) Population kinetics of tobramycin in neonates. Ther Drug Monit 23:202-208
11. Parkin JM, Hey EN, Clowes JS (1976) Rapid assessment of gestational age at birth. Arch Dis Child 51:259-263
12. Sheiner LB, Rosenberg B, Marathe W (1977) Estimation of population characteristics of pharmacokinetic parameters from routine clinical data. Clin Pharmacokinet Biopharm 5:445-479
13. Beal SL, Sheiner LB (1980) The NONMEM System. Am Stat 34:118-119
14. NONMEM Project Group (1992) NONMEM Users Guides. Beal SL, Sheiner LB (eds), University of California at San Francisco, San Francisco
15. Kenyon CF, Knoppert DC, Lee SK, Vandenberghe HM, Chance GW (1990) Amikacin pharmacokinetics and suggested dosage modifications for the preterm infant. Antimicrob Agents Chemother 34:265-268
16. Hentschel R, Lodige B, Bulla M (1996) Renal insufficiency in the neonatal period. Clin Nephrol 46:54-58
17. Moore L, Williams R, Staples A (1993) Glomerular dimensions in children under 16 years of age. J Pathol 171:145-150