Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs

Diabetes

Volumn 53, Issue 1, 2004, Pages 14-20

  Moore, Mary Courtney ^a   Geho, W Blair ^b   Lautz, Margaret ^a   Farmer, Ben ^a   Neal, Doss W ^a   Cherrington, Alan D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SDG   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; GLUCAGON; GLUCOSE; INSULIN; SEROTONIN; SEROTONIN AGONIST; SODIUM CHLORIDE; SOMATOSTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DIET RESTRICTION; DRUG BLOOD LEVEL; DRUG EFFECT; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INFUSION; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; HYPERGLYCEMIA; LIVER LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; STATISTICAL SIGNIFICANCE; TIME;

ANIMALS; BLOOD GLUCOSE; CATECHOLAMINES; DOGS; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCAGON; GLYCEROL; HYDROCORTISONE; INFUSIONS, INTRAVENOUS; KINETICS; LACTATES; MALE; MODELS, ANIMAL; PORTAL SYSTEM; SEROTONIN;

EID: 0347990605     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.1.14     Document Type: Article

References (34)

1. Hanefeld M, Temelkova-Kurktschiev T: Control of post-prandial hyperglycemia - an essential part of good diabetes treatment and prevention of cardiovascular complications. Nutr Metab Cardiovasc Dis 12:98-107, 2002
2. Goodnick PJ, Henry JH, Buki VMV: Treatment of depression in patients with diabetes mellitus. J Clin Psychiatry 56:128-136, 1995
3. Pestell RG, Crock PA, Ward GM: Fenfluramine increases insulin action in patients with NIDDM. Diabetes Care 12:252-258, 1989
4. Endo Y: Induction of hypoglycaemia and accumulation of 5-hydroxytryptamine in the liver after the injection of mitogenic substances into mice. Br J Pharmacol 81:645-650, 1984
5. Endo Y: Evidence that the accumulation of 5-hydroxytryptamine in the liver but not in the brain may cause the hypoglycaemia induced by 5-hydroxytryptophan. Br J Pharmacol 85:591-598, 1985
6. Pagliassotti MJ, Holste LC, Moore MC, Neal DW, Cherrington AD: Comparison of the time courses of insulin and the portal signal on hepatic glucose and glycogen metabolism in the dog. J Clin Invest 97:81-91, 1996
7. Myers SR, Biggers DW, Neal DW, Cherrington AD: Intraportal glucose delivery enhances the effects of hepatic glucose load on net hepatic glucose uptake in vivo. J Clin Invest 88:158-167, 1991
8. Ahlman H, Bhargava HN, Dahlstrom A, Larsson I, Newson B, Pettersson G: On the presence of serotonin in the gut lumen and possible release mechanisms. Acta Physiol Scand 112:263-269, 1981
9. Forsberg EJ, Miller RJ: Cholinergic agonists induce vectorial release of serotonin from duodenal enterochromaffin cells. Science 217:355-356, 1982
10. Bearcroft CP, Perrett D, Farthing MJ: Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: a pilot study. Gut 42:42-46, 1998
11. Satake S, Moore MC, Igawa K, Converse M, Farmer B, Neal DW, Cherrington AD: Direct and indirect effects of insulin on glucose uptake and storage by the liver. Diabetes 51:1663-1671, 2002
12. Pussard E, Guigueno N, Adam O, Giudicelli JF: Validation of HPLC-amperometric detection to measure serotonin in plasma, platelets, whole blood, and urine. Clin Chem 42:1086-1091, 1996
13. Jernej B, Banovic M, Cicin-Sain L, Hranilovic D, Balija M, Oreskovic D, Folnegovic-Smalc V: Physiological characteristics of platelet/circulatory serotonin: study on a large human population. Psychiatry Res 94:153-162, 2000
14. Martin FJ, Miguez JM, Aldegunde M, Atienza G: Platelet serotonin transport is altered in streptozotocin-induced diabetic rats. Life Sci 56:1807-1815, 1995
15. Martin FJ, Miguez JM, Aldegunde M, Atienza G: Effect of streptozotocin-induced diabetes mellitus on serotonin measures of peripheral tissues in rats. Life Sci 56:51-59, 1995
16. Nishizawa M, Moore MC, Shiota M, Gustavson SM, Snead WL, Neal DW, Cherrington AD: Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs. Am J Physiol Endocrinol Metab 284: E1027-E1036, 2003
17. Cowan JS, Hetenyi G Jr: Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method. Metabolism 20:360-372, 1971
18. Steele R, Wall JS, DeBodo RC, Altszuler N: Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am J Physiol 187:15-24, 1956
19. Hsieh PS, Moore MC, Neal DW, Emshwiller M, Cherrington AD: Rapid reversal of the effects of the portal signal under hyperinsulinemic conditions in the conscious dog. Am J Physiol 276:E930-E937, 1999
20. Hsieh PS, Moore MC, Neal DW, Venson P, Cherrington AD: Hepatic glucose uptake rapidly decreases after elimination of the portal signal in conscious dogs. Am J Physiol 275:E987-E992, 1998
21. 2C receptors. Br J Pharmacol 115:622-628, 1995
22. Niijima A: Visceral afferents and metabolic function. Diabetologia 20 (Suppl.):325-330, 1981
23. Niijima A: Afferent impulse discharges from glucoreceptors in the liver of the guinea pig. Ann N Y Acad Sci 157:690-700, 1969
24. Wilson GA, Furman BL: Effects of inhibitors of 5-hydroxytryptamine uptake on plasma glucose and their interaction with 5-hydroxytryptophan in producing hypoglycaemia in mice. Eur J Pharmacol 78:263-270, 1982
25. Lundquist I, Ekholm R, Ericson LE: Monoamines in the pancreatic islets of the mouse: 5-hydroxytryptamine as an intracellular modifier of insulin secretion, and the hypoglyeaemic action of monoamine oxidase inhibitors. Diabetologia 7:414-422, 1971
26. Furman BL: The hypoglycaemic effect of 5-hydroxytryptophan. Br J Pharmacol 50:575-578, 1974
27. Erenmemisoglu A, Ozdogan UK, Saraymen R, Tutus A: Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice. J Pharm Pharmacol 51:741-743, 1999
28. Rattigan S, Dora KA, Colquhoun EQ, Clark MG: Serotonin-mediated acute insulin resistance in the perfused rat hindlimb but not in incubated muscle: a role for the vascular system. Life Sci 53:1545-1555, 1993
29. Hajduch E, Rencurel F, Balendran A, Batty IH, Downes CP, Hundal HS: Serotonin (5-hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle. J Biol Chem 274:13563-13568, 1999
30. Sercombe R, Sercombe C, Oudart N, Seylaz J: Critical role of endothelial nitric oxide synthase and cyclooxygenase in response of rabbit basilar artery to serotonin. Jpn J Pharmacol 90:67-76, 2002
31. Clerk LH, Smith ME, Rattigan S, Clark MG: Nonnutritive flow impairs uptake of fatty acid by white muscles of the perfused rat hindlimb. Am J Physiol Endocrinol Metab 284:E611-E617, 2003
32. Heitkemper M, Jarrett M, Cain K, Shaver J, Bond E, Woods NF, Walker E, Bond EF, Chang L: Increased urine catecholamines and cortisol in women with irritable bowel syndrome. Am J Gastroenterol 91:906-913, 1996
33. Yamada J, Sugimoto Y, Yoshikawa T, Horisaka K: Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor. Eur J Pharmacol 323:235-240, 1997
34. Geho WB, Lau JR: Hepatocyte directed vesicle delivery system. U.S. Patent Office, Technology Unlimited, Inc., 1986