Thought Disorder in Schizophrenia: Working Memory and Impaired Context

Journal of Nervous and Mental Disease

Volumn 192, Issue 1, 2004, Pages 3-11

  Harrow, Martin ^a   Jobe, Thomas H ^a   Herbener, Ellen S ^a   Goldberg, Joseph F ^b   Kaplan, Kalman J ^a,c  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b ZUCKER HILLSIDE HOSPITAL   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE DISEASE; ADULT; ARTICLE; BIPOLAR MANIA; FEMALE; HOSPITAL PATIENT; HUMAN; LEARNING DISORDER; MAJOR CLINICAL STUDY; MALE; MEMORY CONSOLIDATION; SCHIZOPHRENIA; THOUGHT DISORDER; WORKING MEMORY;

ADULT; ASSOCIATION LEARNING; ATTENTION; BIPOLAR DISORDER; COGNITION DISORDERS; DISCRIMINATION LEARNING; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; PATTERN RECOGNITION, VISUAL; PSYCHOMETRICS; PSYCHOTIC DISORDERS; REPRODUCIBILITY OF RESULTS; RETENTION (PSYCHOLOGY); SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SYMBOLISM; THINKING;

EID: 0347763402     PISSN: 00223018     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.nmd.0000105994.78952.b6     Document Type: Article

References (63)

1. Andreasen NJ, Powers PS (1995) Creativity and psychosis: an examination of conceptual style. Arch Gen Psychiatry. 32:70-73.
2. Baddeley AD (2001) Is working memory still working? Am Psychologist. 56:851-864.
3. Baddeley AD, Hitch GJ (1994) Developments in the concept of working memory. Neuropsychology. 8:485-493.
4. Barch DM, Carter CS (1998) Selective attention in schizophrenia: relationship to verbal working memory. Schizophrenia Res. 33:53-61.
5. Bartok J, Martin EM, Pitrak DL, Novak RM, Pursell KJ, Mullane KM, Harrow M (1997) Working memory deficits in HIV seropositive drug users. J Intl Neuropsycholog Society. 3:451-456.
6. Berridge KC, Robinson TE (1998) What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Research-Brain Research Reviews. 28:309-369.
7. Brundege JM, Williams JT (2002) Differential modulation of nucleus accumbens synapses. J Neurophysiology. 88:142-151.
8. Cohen JD, Servan-Schreiber D (1992) Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia. Psychological Rev. 99:45-77.
9. rd ed.). New York, NY: John Wiley and Sons.
10. Frith C, Done J (1988) Toward a neuropsychology of schizophrenia. Br J Psychiatry. 153:437-443.
11. Gabrielli JDE, Singh J, Stebbins GT, Goetz CG (1996) Reduced working memory span in Parkinson's disease: evidence for the role of a frontostriatal system in working and strategic memory. Neuropsychology. 10:322-332.
12. Gathercole SE (1996) Models of short-term memory. Hove, England: Psychology Press.
13. Gjerde PF (1983) Attentional capacity dysfunction and arousal in schizophrenia. Psych Bull. 93:57-72.
14. Gold JM, Carpenter W, Randolph C, Goldberg TE, Weinberger DR (1997) Auditory working memory and Wisconsin Card Sorting Test Performance in schizophrenia. Arch Gen Psychiatry. 54:159-165.
15. Goldberg TE, Aloia MA, Gourovitch M,. Missar D, Pickar D, Weinberger DR (1998) Cognitive substrates of thought disorder: 1. the semantic system. Am J Psychiatry. 155:1671-1676.
16. Goldberg TE, Weinberger DR (2000) Thought disorder in schizophrenia: A reappraisal of older formulations and an overview of some recent studies. Cogtitive Neuropsychiatry. 5:1-19.
17. Goldman-Rakic PS (1987) Circuitry of primate prefrontal cortex and regulation of behavior by representational knowledge. In: Plum F, Mountcastle V, eds Handbook of Physiology: The Nervous System. Bethesda, MD: American Physiological Society: 373-417.
18. Goldman-Rakic PS (1994) Working memory dysfunction in schizophrenia. J Neuropsychiatry Clinical Neurosciences. 6:348-357.
19. Gordon R, Silverstein ML, Harrow M (1982) Associative thinking in schizophrenia: a contextualist approach. J Clinical Psychology. 38:684-696.
20. Grossman LS, Harrow M (1996) Interactive behavior in bipolar manic and schizophrenic patients and its link to thought disorder. Comprehensive Psychiatry. 43:245-252.
21. Grinker RRSr., Harrow M. (eds.) (1987) A Multidimensional Approach to Clinical Research in Schizophrenia. Springfield, IL: Charles C. Thomas, Publisher.
22. Harrow M, Green KE, Sands JR, Jobe TH, Goldberg JF, Kaplan KJ, Martin EM (2000a) Thought disorder in schizophrenia and mania: impaired context. Schizophrenia Bulletin. 26:879-891.
23. Harrow M, Grossman LS, Herbener ES, Davies GW (2000b) Ten year outcome: patients with schizoaffective disorders, schizophrenia, affective disorders, and mood-incongruent, psychotic symptoms. Br J Psychiatry. 177:421-426.
24. Harrow M, Lanin-Kettering I, Miller JG (1989) Impaired perspective and thought pathology in schizophrenic and psychotic disorders. Schizophrenia Bull. 15:605-623.
25. Harrow M, Lanin-Kettering I, Prosen M, Miller SG (1983) Disordered thinking in schizophrenia: intermingling and loss of set. Schizophrenia Bull. 9:354-367.
26. Harrow M, MacDonald III AW, Sands JR, Silverstein ML (1995) Vulnerability to delusions over time in schizophrenia, schizoaffective and bipolar and unipolar affective mood disorders at followup. Schizophrenia Bull. 21:95-109.
27. Harrow M, Marengo J, Pogue-Geile M, Pawelski T (1987) Schizophrenic deficits in intelligence and abstract thinking: influence of aging and long-term institutionalization. In N. Miller (Ed.), Schizophrenia, Paranoia, and Schizophreniform Disorders in Later Life (pp. 133-144). New York: Guilford Press.
28. Harrow M, Miller J (1980) Schizophrenic thought disorders and impaired perspective. J Ab Psychology. 89:717-727.
29. Harrow M, O'Connell EM, Herbener ES, Altman AM, Jobe TH. Disordered verbalizations in schizophrenia: a speech disturbance or thought disorder? Comp Psychiatry. 44:353-359.
30. Harrow M, Quinlan D (1985) Disordered Thinking and Schizophrenic Psychopathology. Gardner Press Inc., New York.
31. Harrow M, Rattenbury FR, Marengo J, King G (1999) A Manual to Assess Positive Thought Disorder, Using the Object Sorting Test. National Auxiliary Publication Service #05507, 1-59, Microfiche Publications, New York.
32. Harrow M, Rattenbury F, Stoll F (1988) Schizophrenic delusions. In T Oltmans, BA Maher (eds). Delusional Beliefs: Interdisciplinary Perspectives. 184-211. New York, Wiley.
33. Harrow M, Sands JR, Silverstein ML, Goldberg JF (1997) Course and outcome for schizophrenia vs. other psychotic patients: a longitudinal study. Schizo Bull. 23:287-303.
34. Holinger DP, Shenton ME, Wible CG, Donnino BS, Kikinis R, Jolesz F, McCarley RW (1999) Superior temporal gyrus volume abnormalities and thought disorder in left-handed schizophrenic men. Am J Psychiatry. 156:1730-1735.
35. Holzman PS, Shenton ME, Solovay MR (1986) Quality of thought disorder in differential diagnosis. Schizo Bull. 12:360-371.
36. Jobe T, Harrow M (2000) Delusions. In AE Kadzin (Ed.) Encyclopedia of Psychology. 467-469, Oxford University Press, New York, N. Y.
37. Kapur S (2003) Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. Am J Psychiatry. 160:13-23.
38. Landre NA, Taylor MA (1995) Formal thought disorder in schizophrenia: linguistic, attentional and intellectual correlates. J Nerv Ment Dis. 183:673-680.
39. LeDoux J (1996) The Emotional Brain. New York, NY: Simon and Schuster.
40. Luck SJ, Vogel EK (1997) The capacity of visual working memory for features and conjunctions. Nature. 390:279-281.
41. Maass W. (2000) Neural computation with winner-take-all as the only nonlinear operation. In S Solla, T Leen, Klaus-Robert Müller (eds), Advances in Information Processing Systems. 12:293-299. MIT Press, Cambridge, MA.
42. Marengo J, Harrow M (1997) The Longitudinal Courses of Thought Disorder in Schizophrenia and Schizoaffective Disorder. Schizo Bull. 23:273-285.
43. Marengo J, Harrow M, Lanin-Kettering IB, Wilson A (1986) A comprehensive index of positive thought disorder. Schizo Bull. 12:497-511.
44. McGrath J (1991) Ordering thoughts on thought disorder. Br J Psychiatry. 158:307-316.
45. Park S, Holzman PS (1992) Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry. 49:975-982.
46. Paulesu E, Frith CD, Frackowiak RSJ (1993) The neural correlates of the verbal component of working memory. Nature. 362:342-345.
47. Plagnol A, Pachoud B, Claudel B, Granger B (1996) Functional disorganization of representations in schizophrenia. Schizo Bull. 22:343-398.
48. Port J, Harrow M, Jobe T, Dougherty D (1997) Thought disorder in adolescent schizophrenics: toward an integrative model. In: L Flaherty, H Horowitz (ed.) Adolescent Psychiatry. 21:119-164 Hillsdale, NJ; Analytic Press.
49. Prabhakaran V, Narayanan K, Zhao Z, Gabrielli JDE (2000) Integration of diverse information in working memory in the frontal lobe. Nature Neuroscience. 3:85-90.
50. Racenstein J, Penn D, Harrow M, Schlessor R (1999) Thought disorder and psychological functioning in schizophrenia: concurrent and predictive relationships. J Nerv Ment Dis. 187:281-289.
51. Rapaport D, Gill MM, Schafer R (1968) Diagnostic Psychological Testing Vol. 2 Chicago: Year Book Publishers, 1946. (Rev. ed), New York: International Universities Press.
52. Rappole K, Harrow M, Uziel N (1995) The assessment of maintenance of context: a scoring manual of responses to verbal tests, unpublished manuscript.
53. Rizzo L, Danion JM, Van DerLinden M, Grange D, Rohmer JG (1996) Impairment of memory for spatial context in schizophrenia. Neuropsychology. 10:376-384.
54. Sands JR, Harrow M (1994) Psychotic unipolar depression at followup: factors related to psychosis in the affective disorders. Am J Psychiatry. 151:995-1000.
55. Shakow D (1962) Segmental set. Arch Gen Psych. 6:1-17.
56. Shenton ME, Kikinis R, Jolesz FA, Pollak SD, LeMay M, Wible CG, Hokama H, Martin J, Metcalf D, Coleman M, McCarley RW (1992) Abnormalities of the left temporal lobe and thought disorder in schizophrenia a quantitative magnetic resonance imaging study. NEJM. 327:604-612.
57. Silverstein ML, Harrow M (1980) Auditory misperceptions of word-association stimuli in schizophrenia. Percept Motor Skills. 50:1192-1194.
58. Silverstein SM, Kovacs I, Corry R, Valone C (2000) Perceptual organization, the disorganization syndrome, and context processing in chronic schizophrenia. Schizophrenia Res. 43:11-20.
59. Silverstein SM, Schenkel LS (1997) Schizophrenia as a model of context-deficient cortical computation. Behav Brain Sciences. 20:696-697.
60. Smith EE, Jonides J, Koeppe RA, Awh E, Schumacher EH, Minoshima S (1995) Spatial versus object working memory: PET investigations. J Cog Neuroscience. 7:337-356.
61. Spitzer M (1997) A cognitive neuroscience view of schizophrenic thought disorder. Schizo Bull. 23:29-50.
62. Spitzer M (1999) The Mind within the Net. MIT Press, Cambridge, MA.
63. Stone M, Gabrielli JDE, Stebbins GT, Sullivan EV (1998) Working and strategic memory deficits in schizophrenia. Neuropsychology. 12:278-288.