In a population study, can parathyroid hormone aid the definition of adequate vitamin D status? A study of people aged 65 years and over from the British National Diet and Nutrition Survey

Osteoporosis International

Volumn 14, Issue 2, 2003, Pages 152-159

  Bates, C J ^a   Carter, G D ^b   Mishra, G D ^a   O'Shea, D ^c   Jones, J ^d   Prentice, A ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^d CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

25 Hydroxyvitamin D; British; Elderly; Parathyroid hormone; Season; Survey

Indexed keywords

25 HYDROXYERGOCALCIFEROL; CALCIUM; PARATHYROID HORMONE; SERUM ALBUMIN; VITAMIN D;

AGE DISTRIBUTION; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CALCIUM BLOOD LEVEL; CALCIUM INTAKE; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; GEOGRAPHIC DISTRIBUTION; HEALTH STATUS; HORMONE DETERMINATION; HUMAN; MALE; NURSING HOME; NUTRITIONAL HEALTH; PARATHYROID HORMONE BLOOD LEVEL; PHYSICAL ACTIVITY; PREDICTION; PRIORITY JOURNAL; SEASONAL VARIATION; SELF REPORT; SUN EXPOSURE; SUNLIGHT; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

AGED; AGED, 80 AND OVER; FEMALE; GREAT BRITAIN; HUMANS; MALE; NUTRITION SURVEYS; NUTRITIONAL STATUS; PARATHYROID HORMONE; VITAMIN D;

EID: 0347752116     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00198-002-1338-3     Document Type: Article

References (38)

1. Department of Health. Nutrition and bone health with particular reference to calcium and vitamin D. Report on health and social subjects no. 49. London: The Stationery Office, 1998.
2. Utiger RD. The need for more vitamin D. N Engl J Med 1998;338:828-9.
3. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes of the Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for calcium, phosphorus, magnesium, vitamin D and fluoride. Washington, DC: National Academy Press, 1997.
4. Department of Health. Dietary reference values for food energy and nutrients for the United Kingdom. Report on health and social subjects no. 41. London: HMSO, 1991.
5. Dawson-Hughes B, Harris SS, Dallal GE. Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elderly men and women. Am J Clin Nutr 1997;65:67-71.
6. Lips P, Wiersinga A, van Ginkel FC, et al. The effect of vitamin D supplementation on vitamin D status and parathyroid function in elderly subjects. J Clin Endocrinol Metab 1988;67:644-50.
7. Lips P, Duong T, Oleksik A, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. J Clin Endocrinol Metab 2001;86:1212-21.
8. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001;22:477-501.
9. Kinyamu HK, Gallagher JC, Rafferty KA, Balhorn KE. Dietary calcium and vitamin D intake in elderly women: effect on serum parathyroid hormone and vitamin D metabolites. Am J Clin Nutr 1998;67:342-8.
10. Chapuy MC, Preziosi P, Maamer M, et al. Prevalence of vitamin D insufficiency in an adult population. Osteoporos Int 1997;7:439-43.
11. Heaney RP. Lessons for nutritional science from vitamin D. Am J Clin Nutr 1999;69:825-6.
12. McKenna MJ, Freaney R. Secondary hyperparathyroidism in the elderly: means to defining hypovitaminosis D. Osteoporos Int 1998;8(Suppl):S3-6.
13. Need AG, Horowitz M, Morris HA, Nordin BC. Vitamin D status: effects on parathyroid hormone and 1,25-dihydroxyvitamin D in postmenopausal women. Am J Clin Nutr 2000;71:1577-81.
14. Ooms ME, Roos JC, Bezemer PD, van der Vijgh WJF, Bouter LM, Lips P. Prevention of bone loss by vitamin D supplementation in elderly women: a randomised double blind trial. J Clin Endocrinol Metab 1995;80:1052-8.
15. Reginster J-Y, Frederick I, Deroisy R, et al. Parathyroid hormone plasma concentrations in response to low 25-OH-vitamin D circulating levels increases with age in elderly women. Osteoporos Int 1998;8:390-2.
16. Souberbielle J-C, Cormier C, Kindermans C, et al. Vitamin D status and redefining serum parathyroid hormone reference range in the elderly. J Clin Endocrinol Metab 2001;86:3086-90.
17. Reichel H, Koeffler HP, Norman AW. The role of the vitamin D endocrine system in health and disease. N Engl J Med 1989;320:980-1.
18. Solanki T, Hyatt RH, Kemm JR, Hughes EA, Cowan RA. Are elderly Asians in Britain at a high risk of vitamin D deficiency and osteomalacia? Age Ageing 1995;24:103-7.
19. Malabanan A, Veronikis IE, Holick MF. Redefining vitamin D insufficiency. Lancet 1998;351:805-6.
20. Finch S, Doyle W, Lowe C, et al. National Diet and Nutrition Survey: people aged 65 years or over. Vol 1. Report of the Diet and Nutrition Survey. London: The Stationery Office, 1998.
21. 125I-labelled tracer. Clin Chem 1993;39:529-33.
22. Carter GD, Nolan J, Trafford DJ, Makin HL. Gas chromatography mass spectrometry (GC-MS) target values in the international quality assessment scheme (EQAS) for 25-hydroxyvitamin D. In: Norman AW, Bouillon R, Thomasset M, editors. Vitamin D: chemistry, biology and clinical applications of the steroid hormone: proceedings of the Tenth Workshop on Vitamin D. 1997, 737-8.
23. Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc 1979;74:829-36.
24. Mathsoft S-PLUS reference manual, vol 1. Seattle, WA: Mathsoft, 1995.
25. Venables WN, Ripley BD. Modern applied statistics with S-PLUS. Berlin Heidelberg New York: Springer, 1997.
26. Payne RB, Carver ME, Morgan DB. Interpretation of serum total calcium: effects of adjustment for albumin concentration on frequency of abnormal values and on detection of change in the individual. J Clin Pathol 1979;32:56-60.
27. Tibblin S, Palsson N, Rydberg J. Hyperparathyroidism in the elderly. Ann Surg 1983;197:135-8.
28. Blichert-Toft M, Mollerup CL, Feldt-Rasmussen UF, Daugaard H, Engel UH. Primary hyperparathyroidism. An under-diagnosed disease in Denmark? Ugeskr Laeger 1993;155:765-9.
29. Lundgren E, Rastad J, Thurfjell E, Akerstrom G, Ljunghall S. Population-based screening for primary hyperparathyroidism with serum calcium and parathyroid hormone values in menopausal women. Surgery 1997;121:287-94.
30. 3 [abstract]. J Clin Endocrinol Metab 1994;79:211-6.
31. 3 intake exceeding the lowest observed adverse effect level. Am J Clin Nutr 2001;73:288-94.
32. 2D] action. J Clin Endocrinol Metab 2000;85:4023-7.
33. McKane R, Khosla S, Egan KS, Robins SP, Burritt MF, Riggs BL. Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab 1996;81:1699-703.
34. Clements MR, Johnson L, Fraser DR. A new mechanism for induced vitamin D deficiency in calcium deprivation. Nature 1987;325:62-5.
35. Bates CJ, Mansoor MA, van der Pols J, Prentice A, Cole TJ, Finch S. Plasma total homocysteine in a representative sample of 972 British men and women aged 65 and over. Eur J Clin Nutr 1997;51:691-7.
36. Davies PSW, Bates CJ, Cole TJ, Prentice A, Clarke PC. Vitamin D: seasonal and regional differences in preschool children in Great Britain. Eur J Clin Nutr 1999;53:195-8.
37. 6 status in older British people. Int J Vit Nutr Res 1999;69:371-7.
38. Bates CJ, Prentice A, van der Pols JC, et al. Estimation of the use of dietary supplements in the National Diet and Nutrition Survey: people aged 65 years and over. An observed paradox and a recommendation. Eur J Clin Nutr 1998;52:917-23.