Effects of phencyclidines on signal transfer from the entorhinal cortex to the hippocampus in rats

Neuroscience Letters

Volumn 354, Issue 3, 2004, Pages 185-188

  Dugladze, Tamar ^a   Lepsveridze, Eka ^a,b   Breustedt, Jörg ^a   Kehrer, Colin ^a   Heinemann, Uwe ^a   Gloveli, Tengis ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Entorhinal cortex; Field potential; High frequency stimulation; Hippocampus; MK 801; Rats

Indexed keywords

DIZOCILPINE; PHENCYCLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC POTENTIAL; ENTORHINAL CORTEX; EVOKED RESPONSE; FEMALE; HIPPOCAMPUS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPSE;

EID: 0347683382     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2003.10.008     Document Type: Article

References (9)

1. Andreasen N.C. Schizophrenia: the fundamental questions. Brain Res. Brain Res. Rev. 31:2000;106-112.
2. Colbert C.M., Levy W.B. Electrophysiological and pharmacological characterisation of perforant path synapses in CA1: mediation by glutamate receptors. J. Neurophysiol. 68:1992;1-8.
3. Empson R.M., Heinemann U. Perforant path connections to area CA1 are predominantly inhibitory in the rat hippocampal-entorhinal cortex combined slice preparation. Hippocampus. 5:1995;104-107.
4. Gloveli T., Iserhot C., Schmitz D., Castren E., Behr J., Heinemann U. Systemic administration of the phencyclidine compound MK-801 affects stimulus-induced field potentials selectively in layer III of rat medial entorhinal cortex. Neurosci. Lett. 221:1997;93-96.
5. Gloveli T., Schmitz D., Empson R.M., Heinemann U. Frequency-depended information flow from the entorhinal cortex to the hippocampus. J. Neurophysiol. 78:1997;3444-3449.
6. Jacob H., Beckmann H. Circumscribed malformation and nerve cell alterations in the entorhinal cortex of schizophrenics. Pathogenetic and clinical aspects. J. Neural Transm. 98:1994;83-106.
7. Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry. 148:1991;1301-1308.
8. Olney J.W., Labruyere J., Price M.T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science. 244:1989;1360-1362.
9. Witter M.P. Organization of the entorhinal-hippocampal system: a review of current anatomical data. Hippocampus. 3:1993;33-44.