Mutation in the STR Locus D21S11 of Father Causing Allele Mismatch in the Child

Journal of Forensic Sciences

Volumn 49, Issue 1, 2004, Pages 99-103

  Thangaraj, Kumarasamy ^a   Reddy, Alla G ^a   Singh, Lalji ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

CSF1PO; D13S317; D16S539; D18S51; D21S11; D3S1358; D5S818; D7S820; D8S1179; DNA sequencing; DNA typing; DYS19; DYS389I; FGA; Forensic science; Mutation; Paternity index; Paternity test; Penta D; Penta E; Plasmid cloning; Short tandem repeats; THO1; TPOX; VWA; Y chromosome

Indexed keywords

PLASMID DNA;

ALLELE; ARTICLE; BLOOD SAMPLING; DNA DETERMINATION; DNA FINGERPRINTING; DNA SEQUENCE; GENE LOCUS; GENE MUTATION; GENOTYPE; HUMAN; MOLECULAR CLONING; PATERNITY; PATERNITY TEST; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SHORT TANDEM REPEAT; Y CHROMOSOME;

EID: 0347651759     PISSN: 00221198     EISSN: None     Source Type: Journal    
DOI: 10.1520/jfs2002236     Document Type: Article

References (16)

1. Gill P, Ivanov PL, Kimpton C, Piercy R, Benson N, Tully G, et al. Identification of the remains of the Romanov family by DNA analysis. Nat Genet 1994;6:130-5.
2. Urquhart A, Kimpton CP, Downes TJ, Gill P. Viriation in short tandem repeat sequences-a survey of twelve microsatellite loci for use as forensic identification markers. Int J Leg Med 1994;107:13-20.
3. Patrizio P, Leonard DGB, Chen K-L, Ayup SH, Trounson AO. Larger trinucleotides repeat size in the androgen receptor gene of infertile men with extremely severe oligozoospermia. J Androl 2001;22:444-8.
4. Sinden RR. Biological implications of the DNA structures associated with disease causing triplet repeats. Am J Hum Genet 1999;31:346-53.
5. McMurray CT. Mechanisms of DNA expansion. Chromosoma 1995; 104:2-13.
6. Wells RD. Molecular basis of genetic instability of triplet repeats. J Biol Chem 1996;271:2875-8.
7. Thangaraj K, Joshi M, Reddy AG, Gupta NJ, Chakravarty B, Singh L. CAG repeat expansion in the androgen receptor gene is not associated with male infertility in Indian populations. J Androl 2002;23:815-8.
8. Thangaraj K, Ramana GV, Singh L. Y-chromosome and mitochondrial DNA polymorphisms in Indian populations. Electrophoresis 1999;20: 1743-7.
9. Thangaraj K, Joshi MB, Reddy AG, Rasalkar AA, Singh L. Sperm mitochondrial mutation as a cause of low sperm motility. J Androl 2003; 24:388-92.
10. Bridge PJ. The calculation of genetic risk. Worked examples in DNA diagnostics. 2nd ed. Maryland: The John Hopkins University Press, 1997;175-84.
11. Ashma R, Kashyap VK. Genetic polymorphism at 15 STR loci among three important subpopulations of Bihar, India. Forensic Sci Intl 2002; 13058-62.
12. Levedakou EN, Freeman DA, Budzynski MJ, Early BE, McElfresh KC, Schumm JW, et al. Allele frequencies for fourteen STR loci of the PowerPlex™ 1.1 and 2.1 Multiplex systems and Penta D locus in Caucasians, African-Americans, Hispanics, and other populations of the United States of America and Brazil. J Forensic Sci 2001;64: 89-95.
13. Weber JL, Wong C. Mutation of human short tandem repeats. Hum Mol Genet 1993;2:1123-8.
14. Brinkmann B, Klintschar M, Neuhuber F, Huhne J, Rolf B. Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat. Am J Hum Genet 1998;62:1408-15.
15. Brinkmann B, Meyer E, Junge A. Complex mutational events at the HumD21S11 locus, Hum Genet 1996;98:60-4.
16. Xiao F-X, Gilissen A, Cassiman J-J, Decorty R. Quadruplex fluorescent STR typing system (HUMVWA, HUMTHO1, D21S11 and HPRT) with sequence-defined allelic ladders identification of a new allele at D21S11. Forensic Sci Intl 1998;94:39-46.