Destabilization of the Escherichia coli RNase H Kinetic Intermediate: Switching between a Two-state and Three-state Folding Mechanism

Journal of Molecular Biology

Volumn 335, Issue 2, 2004, Pages 609-618

  Spudich, Giulietta M ^a,b   Miller, Erik J ^a   Marqusee, Susan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Energy landscape; Folding intermediates; Protein folding; Protein stability; Ribonuclease H

Indexed keywords

BACTERIAL ENZYME; MUTANT PROTEIN; RIBONUCLEASE H;

ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROPHOBICITY; MOLECULAR MECHANICS; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY;

ESCHERICHIA COLI;

EID: 0347627528     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.10.052     Document Type: Article

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