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Volumn 17, Issue 3, 2003, Pages

ING N 201: Ad-p53, Ad5CMV-p53, adenoviral p53, INGN 101, p53 gene therapy - Introgen, RPR/INGN 201
[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; ADENOVIRUS VECTOR; ADVEXIN; CISPLATIN; ORPHAN DRUG; PROTEIN P53; RPR; TAXOID; UNCLASSIFIED DRUG;

EID: 0347625437     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (18)

References (25)
  • 3
    • 85009029956 scopus 로고    scopus 로고
    • Results of first gene therapy study to demonstrate tumor regression and positive safety profile in head and neck cancer pesented at ASCO
    • [3 pages], 19 May
    • Results of first gene therapy study to demonstrate tumor regression and positive safety profile in head and neck cancer pesented at ASCO. PR Newswire [online]: [3 pages], 19 May 1997. Available from URL: http://www.newspage.com
    • (1997) PR Newswire [Online]
  • 5
    • 0002665410 scopus 로고    scopus 로고
    • A phase II trial of adenoviral mediated P53 gene transfer (RPR/INGN 201) in conjunction with radiation therapy in patients with localized non-small cell lung cancer
    • (plus poster), 20 May
    • Swisher S, Roth JA, Komaki R, et al. A phase II trial of adenoviral mediated P53 gene transfer (RPR/INGN 201) in conjunction with radiation therapy in patients with localized non-small cell lung cancer. 36th Annual Meeting of the American Society of Clinical Oncology 19: 461 (plus poster), 20 May 2000
    • (2000) 36th Annual Meeting of the American Society of Clinical Oncology , vol.19 , pp. 461
    • Swisher, S.1    Roth, J.A.2    Komaki, R.3
  • 6
    • 0003079179 scopus 로고    scopus 로고
    • Tolerance and safety of RPR/INGN 201, an adeno-viral vector containing a p53 gene, administered intratumorally in 309 patients with advanced cancer enrolled in phase I and II studies world-wide
    • (plus poster), 20 May
    • Yver A, Dreiling LK, Mohanty S, et al. Tolerance and safety of RPR/INGN 201, an adeno-viral vector containing a p53 gene, administered intratumorally in 309 patients with advanced cancer enrolled in phase I and II studies world-wide. 36th Annual Meeting of the American Society of Clinical Oncology 19: 460 (plus poster), 20 May 2000
    • (2000) 36th Annual Meeting of the American Society of Clinical Oncology , vol.19 , pp. 460
    • Yver, A.1    Dreiling, L.K.2    Mohanty, S.3
  • 7
    • 85009035022 scopus 로고    scopus 로고
    • Introgen's adenoviral vector demonstrates safety in phase II study; biosafety data
    • Media Release: [2 pages], 1 Jun
    • Introgen Therapeutics Inc. Introgen's adenoviral vector demonstrates safety in phase II study; biosafety data presented at American Society of Gene Therapy Meeting. Media Release: [2 pages], 1 Jun 2001. Available from URL: http://www.introgen.com
    • (2001) American Society of Gene Therapy Meeting
  • 9
    • 0000648940 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of intravenous p53 gene therapy with RPR/INGN-201 in patients with advanced cancer
    • 12 May
    • Hao D, Rowinsky EK, Smetzer LA, et al. A phase I and pharmacokinetic study of intravenous p53 gene therapy with RPR/INGN-201 in patients with advanced cancer. 37th Annual Meeting of the American Society of Clinical Oncology 20: 262, Part 1, 12 May 2001
    • (2001) 37th Annual Meeting of the American Society of Clinical Oncology , vol.20 , Issue.PART 1 , pp. 262
    • Hao, D.1    Rowinsky, E.K.2    Smetzer, L.A.3
  • 10
    • 85009034530 scopus 로고    scopus 로고
    • Intratumoral adenoviral-mediated p53 gene therapy is associated with a survival advantage in recurrent squamous cell cancer of the head and neck based on a dose response model using phase 2 data
    • (plus poster), 6 Apr
    • Nemunaitis J, Goodwin WJ, Bier-Laning C, et al. Intratumoral adenoviral-mediated p53 gene therapy is associated with a survival advantage in recurrent squamous cell cancer of the head and neck based on a dose response model using phase 2 data. 93rd Annual Meeting of the American Association for Cancer Research - Supplement: 83 (plus poster), 6 Apr 2002
    • (2002) 93rd Annual Meeting of the American Association for Cancer Research , Issue.SUPPL. 83
    • Nemunaitis, J.1    Goodwin, W.J.2    Bier-Laning, C.3
  • 11
    • 85009031266 scopus 로고    scopus 로고
    • Introgen therapeutics ADVEXIN® gene therapeutic experience highlighted
    • Media Release: 25 Jun
    • Introgen Therapeutics Inc. Introgen Therapeutics ADVEXIN® gene therapeutic experience highlighted at international p53 meeting. Media Release: 25 Jun 2002. Available from URL: http://www.introgen.com
    • (2002) International p53 Meeting
  • 12
    • 0027448548 scopus 로고
    • Inhibition of cell proliferation by an adenovirus vector expressing the human wild type-p53 protein
    • Nov
    • Bacchetti S, Graham FL. Inhibition of cell proliferation by an adenovirus vector expressing the human wild type-p53 protein. International Journal of Oncology 1993 Nov; 3: 781-788
    • (1993) International Journal of Oncology , vol.3 , pp. 781-788
    • Bacchetti, S.1    Graham, F.L.2
  • 13
    • 0028963221 scopus 로고
    • In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
    • Jan
    • Clayman GL, El-Naggar AK, Roth JA, et al. In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Research 1995 Jan; 55: 1-6
    • (1995) Cancer Research , vol.55 , pp. 1-6
    • Clayman, G.L.1    El-Naggar, A.K.2    Roth, J.A.3
  • 14
    • 0030100291 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein
    • Mar-Apr
    • Harris MP, Sutjipto S, Wills KN, et al. Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Therapy 1996 Mar-Apr; 3: 121-130
    • (1996) Cancer Gene Therapy , vol.3 , pp. 121-130
    • Harris, M.P.1    Sutjipto, S.2    Wills, K.N.3
  • 15
    • 0036143665 scopus 로고    scopus 로고
    • The effects of exogenous p53 overexpression on HPV-immortalized and carcinogen transformed oral keratinocytes
    • Jan
    • Yoo GH, Washington J, Oliver J, et al. The effects of exogenous p53 overexpression on HPV-immortalized and carcinogen transformed oral keratinocytes. Cancer 2002 Jan; 94: 159-166
    • (2002) Cancer , vol.94 , pp. 159-166
    • Yoo, G.H.1    Washington, J.2    Oliver, J.3
  • 17
    • 0037746601 scopus 로고    scopus 로고
    • Clinical gene therapy strategies: Phase I/II results with adenoviral P53 (INGN 201) gene transfer in advanced head and neck and non small cell lung cancers
    • 11 Sep
    • Merritt JA, Clayman G, Schwisher S. Clinical gene therapy strategies: phase I/II results with adenoviral P53 (INGN 201) gene transfer in advanced head and neck and non small cell lung cancers. 3rd European Conference on Gene Therapy of Cancer: 175, 11 Sep 1997
    • (1997) 3rd European Conference on Gene Therapy of Cancer , pp. 175
    • Merritt, J.A.1    Clayman, G.2    Schwisher, S.3
  • 18
    • 0001458965 scopus 로고    scopus 로고
    • A phase II multi-center study of AD5CMV-P53 administered intratumorally to patients with recurrent head and neck cancer
    • 15 May
    • Bier-Laning CM, VanEcho D, Yver A. A phase II multi-center study of AD5CMV-P53 administered intratumorally to patients with recurrent head and neck cancer. 35th Annual Meeting of the American Society of Clinical Oncology 18: 444, 15 May 1999
    • (1999) 35th Annual Meeting of the American Society of Clinical Oncology , vol.18 , pp. 444
    • Bier-Laning, C.M.1    VanEcho, D.2    Yver, A.3
  • 21
    • 0033950285 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
    • Feb
    • Nemunaitis J, Swisher SG, Timmons T, et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. Journal of Clinical Oncology 2000 Feb; 18: 609-622
    • (2000) Journal of Clinical Oncology , vol.18 , pp. 609-622
    • Nemunaitis, J.1    Swisher, S.G.2    Timmons, T.3
  • 23
    • 85009030630 scopus 로고    scopus 로고
    • Introgen therapeutics reports progress in gene therapy studies
    • Media Release: [4 pages], 22 May
    • Introgen Therapeutics Inc. Introgen Therapeutics reports progress in gene therapy studies at annual ASCO meeting - gene therapy can be combined with radiation therapy and may improve local. Media Release: [4 pages], 22 May 2000. Available from URL: http://www.introgen.com
    • (2000) Annual ASCO Meeting - Gene Therapy can be Combined with Radiation Therapy and may Improve Local
  • 24
    • 0038422764 scopus 로고    scopus 로고
    • Induction of pro-apoptotic mediators and tumor regression following intratumoral delivery of adenoviral p53 and radiation therapy in patients with non-small cell lung cancer
    • plus poster, 12 May
    • Swisher S, Roth J, Komaki R, et al. Induction of pro-apoptotic mediators and tumor regression following intratumoral delivery of adenoviral p53 and radiation therapy in patients with non-small cell lung cancer. 37th Annual Meeting of the American Society of Clinical Oncology 20: 257 (plus poster), Part 1, 12 May 2001
    • (2001) 37th Annual Meeting of the American Society of Clinical Oncology , vol.20 , Issue.PART 1 , pp. 257
    • Swisher, S.1    Roth, J.2    Komaki, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.