(3R,4S)-3,4,5-Trihydroxy-4-methylpentylphosphonic acid, an isosteric phosphonate analogue of 2-C-methyl-D-erythritol 4-phosphate, a key intermediate in the new pathway for isoprenoid biosynthesis

Tetrahedron Letters

Volumn 45, Issue 3, 2004, Pages 519-521

  Hirsch, Guillaume ^a   Grosdemange Billiard, Catherine ^a   Tritsch, Denis ^a   Rohmer, Michel ^a  

^a CNRS   (France)

Author keywords

1 Deoxy D xylulose reducto isomerase; 2 C Methyl D erythritol 4 phosphate; 2 C Methyl D erythritol 4 phosphate cytidyltransferase; Biosynthesis; Isoprenoids; Phosphonate

Indexed keywords

1,2 O ISOPROPYLIDENE ALPHA DEXTRO XYLOFURANOSE; 2 C METHYL DEXTRO ERYTHRITOL 4 PHOSPHATE; 3,4,5 TRIHYDROXY 4 METHYLPENTYLPHOSPHONIC ACID; ERYTHRITOL; ISOPRENOID; PHOSPHONIC ACID DERIVATIVE; PROPANE; UNCLASSIFIED DRUG; XYLENE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER;

EID: 0347624537     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.11.001     Document Type: Article

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15. +, m/z=485.2093 ; found, m/z=485.2099.
16. +, molecular monoanion of 18 ).
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