Volumetric quantitation by MRI in primary progressive multiple sclerosis: Volumes of plaques and atrophy correlated with neurological disability

European Journal of Neurology

Volumn 10, Issue 6, 2003, Pages 663-669

  Ukkonen, M ^a,b   Dastidar, P ^a   Heinonen, T ^b   Laasonen, E ^a,b   Elovaara, I ^a,b  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Atrophy; Expanded disability status scale; Magnetic resonance imaging; Plaques; Primary progressive multiple sclerosis; Volumetry

Indexed keywords

ADULT; AGED; ARTICLE; AUTOMATION; BRAIN ATROPHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISABILITY; FEMALE; HUMAN; MALE; MOBILIZATION; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RATING SCALE; SCORING SYSTEM; SENILE PLAQUE; SENSORY DYSFUNCTION; SPINAL CORD ATROPHY; VOLUMETRY;

ACTIVITIES OF DAILY LIVING; ADULT; ARM; ATROPHY; BRAIN; CEREBROSPINAL FLUID PRESSURE; DISABILITY EVALUATION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOVEMENT; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; SCLERODERMA, DIFFUSE; SENILE PLAQUES; SPINAL CORD; WALKING;

EID: 0347595377     PISSN: 13515101     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-1331.2003.00617.x     Document Type: Article

References (51)

1. Anderson PB, Waubant E, Gee L, Goodkin DE (1999). Multiple sclerosis that is progressive from the time of onset. Arch Neurol 56:1138-1142.
2. Ciccarelli O, Werring DJ, Wheeler-Kingshott CAM et al. (2001). Investigation of MS normal-appearing brain using diffusion tensor MRI with clinical correlations. Neurology 56:926-933.
3. Comi G, Filippi M, Martinelli V et al. (1993). Brain magnetic resonance imaging correlates of cognitive impairment in multiple sclerosis. J Neurol Sci 115 (suppl):S66-S73.
4. Cottrell DA, Kremenchutzky M, Rice GPA et al. (1999). The natural history of multiple sclerosis: a geographically based study. The clinical features and natural history of primary progressive multiple sclerosis. Brain 122:625-639.
5. Dastidar P, Heinonen T, Lehtimäki T et al. (1999). Volumes of brain atrophy and plaques correlated with neurological disability in secondary progressive multiple sclerosis. J Neurol Sci 165:36-42.
6. Dietemann JL, Thibaut-Menard A, Warter JM et al. (2000). MRI in multiple sclerosis of the spinal cord: evaluation of fast short-tan inversion-recovery and spin echo sequences. Neuroradiology 42:810-813.
7. Dore-Duffy P, Newman W, Balabanov R et al. (1995). Circulating soluble adhesion proteins in cerebrospinal fluid and serum of patients with multiple sclerosis: correlation with clinical acrivity. Ann Neurol 37:55-62.
8. Filippi M, Campi A, Martinelli V et al. (1995a). A brain MRI study of different types of chronic progressive multiple sclerosis. Acta Neurol Scand 91:231-233.
9. Filippi M, Paty DW, Kappos L et al. (1995b). Correlations between changes in disability and T2-weighted brain MRI activity in multiple sclerosis: a follow-up study. Neurology 45:255-260.
10. Filippi M, Campi A, Colombo B et al. (1996). A spinal cord MRI study of benign and secondary multiple sclerosis. J Neurol 243:502-505.
11. Filippi M, Colombo B, Rovaris M, Pereira C, Martinelli V, Comi G (1997). A longitudinal magnetic resonance imaging study of the cervical cord in multiple sclerosis. J Neuroimaging 7:78-80.
12. Filippi M, Mastronardo G, Rocca MA, Pereira C, Comi G (1998). Quantitative volumetric analysis of brain magnetic resonance imaging from patients with multiple sclerosis. J Neurol Sci 158:148-153.
13. Filippi M, Rocca MA, Falini A et al. (2002). Correlations between structural CNS damage and functional MRI changes in primary progressive MS. Neuroimage 15:537-546.
14. Gass A, Barker GJ, Kidd D et al. (1994). Correlation of magnetization transfer ratio with clinical disability in multiple sclerosis. Ann Neurol 36:62-67.
15. Giovannoni G, Thorpe JW, Kidd D et al. (1994). Soluble E-selectin in multiple sclerosis: clinical and MRI correlation. J Neuroimmunol 54:164.
16. Giovannoni G, Thorpe JW, Kidd D et al. (1996). Soluble E-selectin in multiple sclerosis: raised concentrations in patients with primary progressive disease. J Neurol Neurosurg Psychiatry 60:20-26.
17. Heinonen T, Dastidar P, Malmivuo J, Eskola H (1998a). Semiautomatic tool for segmentation and volumetric analyses of medical images. Med Biol Eng Comp 36:291-296.
18. Heinonen T, Dastidar P, Eskola H et al. (1998b). Applicability of semiautomatic segmentation for volumetric analysis of brain lesions. J Med Eng Technol 22:173-178.
19. Hillert J, Grönning M, Nyland H, Link H, Olerup O (1992). An immunogenetic heterogeneity in multiple sclerosis. J Neurol Neurosurg Psychiatry 55:887-890.
20. Jalonen T, Pulkkinen K, Ukkonen M, Saarela M, Elovaara I (2002). Differential intracellular expression of CCR5 and chemokines in multiple sclerosis subtypes. J Neurol 249:576-538.
21. Kidd D, Thorpe JW, Thompson AJ et al. (1993). Spinal cord MRI using multi-array coils and fast spin acho. Findings in multiple sclerosis. Neurology 43:2632-2637.
22. Kidd D, Thorpe JW, Kendall BE et al. (1996). MRI dynamics of brain and spinal cord in progressive multiple sclerosis. J Neurol Neurosurg Psychiatry 60:15-19.
23. Kurtzke JF (1983). Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444-1452.
24. Larsen JP, Kvaale G, Riise T, Nyland H, Aarli JA (1985). Multiple sclerosis - more than one disease? Acta Neurol Scand 72:145-150.
25. Losseff NA, Wang L, Lai HM et al. (1996a). Progressive cerebral atrophy in multiple sclerosis. A serial MRI study. Brain 119:2009-2019.
26. Losseff NA, Webb SL, O'Riordan JI et al. (1996b). Spinal cord atrophy and disability in multiple sclerosis. A new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 119:701-708.
27. Lublin FD, Reingold SC (1996). Denning the clinical course of multiple sclerosis: results of an international survey. Neurology 46:907-911.
28. Lycklama à Nijeholt GJ, Barkhof F, Scheltens P et al. (1997). MR of the spinal cord in multiple sclerosis: relation to clinical subtype and disability. AJNR Am J Neuroradiol 18:1041-1048.
29. Lycklama à Nijeholt GJ, van Walderveen MAA, Castelijns JA et al. (1998). Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms. Brain 121:687-697.
30. Lycklama à Nijeholt GJ, Bergers E, Kamphorst W et al. (2001). Post-mortem high-resolution MRI of the spinal cord in multiple sclerosis. A correlative study with conventional MRI, histopathology and clinical phenotype. Brain 124:154-166.
31. Mainero C, De Stefano N, Iannucci G et al. (2001). Correlates of MS disability assessed in vivo using aggregates of MR quantities. Neurology 56:1331-1334.
32. Mammi S, Filippi M, Martinelli V et al. (1996). Correlation between brain MRI lesion volume and disability in patients with multiple sclerosis. Acta Neurol Scand 94:93-96.
33. McDonnell GV, Hawkins SA (1998). Clinical study of primary progressive multiple sclerosis in Northern Ireland, UK. J Neurol Neurosurg Psychiatry 64:451-454.
34. Minderhoud JM, van der Hoeven JH, Prange AJA (1988). Course and prognosis of chronic progressive multiple sclerosis. Acta Neurol Scand 78:10-15.
35. Munsat T (ed.) (1989). Quantification of Neurological Deficit. Butterworth, Boston, pp. 53-54.
36. Olerup O, Hillert J, Fredrikson S et al. (1989). Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities. Proc Natl Acad Sci USA 86:7113-7117.
37. Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI (1994). A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 117:759-765.
38. Rocca MA, Mastronardo G, Horsfield MA et al. (1999). Comparison of three MR sequences for the detection of cervical cord lesions in patients with multiple sclerosis. AJNR Am J Neuroradiol 20:1710-1716.
39. Rocca MA, Matthews PM, Caputo D et al. (2002). Evidence for widespread movement-associated functional MRI changes in patients with PPMS. Neurology 58:866-872.
40. Rovaris M, Bozzalli M, Santuccio G et al. (2001), In vivo assessment of the brain and cervical cord pathology of patients with primary progressive multiple sclerosis. Brain 124:2540-2549.
41. Sinnige LGF, Teeuwissen E, Hew JM, Minderhoud JM (1995). Correlation between magnetic resonance imaging and clinical parameters in multiple sclerosis. Acta Neurol Scand 91:188-191.
42. Stevenson VL, Leary SM, Losseff NA et al. (1998). Spinal atrophy and disability in MS. A longitudinal study. Neurology 51:234-238.
43. Stevenson VL, Miller DH, Leary SM et al. (2000). One year follow up study of primary and transitional progressive multiple sclerosis. J Neurol Neurosurg Psychiatry 68:713-718.
44. Thompson AJ, Kermode AG, MacManus DG et al. (1990). Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study. Br Med J 300:631-634.
45. Thompson AJ, Kermode AG, Wicks D et al. (1991). Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 29:53-62.
46. Thompson AJ, Polman CH, Miller DH et al. (1997). Primary progressive multiple sclerosis. Brain 120:1085-1096.
47. Thompson AJ, Montalban X, Barkhof F et al. (2000). Diagnostic criteria for primary progressive multiple sclerosis: a position paper. Ann Neurol 47:831-835.
48. van Walderween MAA, Barkhof F, Hommes OR et al. (1995). Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images. Neurology 45:1684-1690.
49. van Walderween MAA, Barkhof F, Tas MW et al. (1998). Patterns of brain magnetic resonance abnormalities on T2-weighted spin echo images in clinical subgroups of multiple sclerosis: a large cross-sectional study. Eur Neurol 40:91-98.
50. van Walderween MAA, Lycklama à Nijeholt GJ, Adèr HJ et al. (2001) Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging. Arch Neurol 58:76-81.
51. Weinshenker BG, Santrach P, Schaid D et al. (1995). Association between class II major histocompatibility complex polymorphisms and the course of multiple sclerosis. Neurology 45:A384.