Modulation of differentiated functions of cultured chondrocytes. Advantages for therapy;La versatilité des fonctions différenciées du chondrocyte articulaire en culture. Intérêt éventuel en thérapeutique

Bulletin de l'Academie Nationale de Medecine

Volumn 184, Issue 3, 2000, Pages 593-604

  Adolphe, Monique ^a   Demignot, Sylvie ^a  

^a Lab de Pharmacologie Respiratoire   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; HUMAN; JOINT; PHYSIOLOGY;

CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; HUMANS; JOINTS;

EID: 0347537618     PISSN: 00014079     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. BENYA P.D., PADILLA S.R., MIMNI M.E. - Independant regulation of collagen types by chondrocytes during the loss of differentiated functions in culture. Cell, 1978, 15, 1313-1321.
2. DUCHENE M., SOBEL M.E., MULLER P.K. - Levels of collagen mRNA in dedifferentiating chondrocytes. Exp. Cell. Res., 1982, 142, 317-324.
3. BORGE L., DEMIGNOT S., ADOLPHE M. Type II transglutaminase expression in rabbit articular chondrocytes in culture ; relation with cell differentiation, cell growth, cell adhesion and cell apoptosis. Biochim. Biophys. Acta, 1996, 1312, 117-124.
4. LEFEBVRE V., PEETERS-JORIS C., VAES G. Production of collagens, collagenase and collagenase inhibitor during dedifferentiation of articular chondrocytes by serial subcultures. Biochim. Biophys. Acta, 1990, 1051, 266-275.
5. BENYA P.D., SHAFFER J.D. - Dediffenentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell, 1982, 30, 215-224.
6. GIBSON G.J., SHOR S.L., GRANT M.E. - Effects of matrix macromolecules on chondrocyte gene expression : synthesis of a low molecular weight collagen species by cells cultured within collagen gels. J Cell Biol., 1982, 93, 767-774.
7. DEWILDE B., BENEL L., HARTMANN D.J., ADOLPHE M. - Subculture of rabbit articular chondrocytes within collagen gel. Growth and analysis of differentiation. Cytotechnology, 1989, 7, 123-132.
8. ADOLPHE M., THENET S., VINCENT F., DEMIGNOT S. - Monolayer, tridimensional and immortalised cell line culture as models in pharmacology and toxicology. Toxicol. In vitro, 1991, 5, 367-371.
9. GUO J., JOURDIAN G.W., MC CALLUM D.K. - Culture and growth characteristics of chondrocytes encapsulated in alginate beads. Connect. Tissue Res., 1989, 19, 277-297.
10. BONAVENTURE J., KADHOM N., COHEN SOLAL L., NGUYEN KH., BOURGUIGNON J., LASSELIN C., FREISINGER P. - Reexpression of cartilage specific genes by dedifferentiated human articular chondrocytes cultured in alginate beads. Exp. Cell Res., 1994, 212, 97-104.
11. LEMAIRE F., STEIMBERG N., LE GRIEL C., DEMIGNOT S., ADOLPHE M. - Dedifferentiated chondrocytes cultured in alginate beads : restoration of the differentiated phenotype and of the metabolic responses to interleukine 1β. J. Cell. Physiol., 1998, 176, 303-313.
12. BENYA P.D., BROWN P.D., PADILLA S.R. - Microfilament modification by DHCB causes retinoic acid modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape. J. Cell Biol., 1988, 106, 161-170.
13. th annual meeting of the orthopaedic research society, 1990, New Orleans, U.S.A.
14. BORGE L., LEMARE F., DEMIGNOT S., ADOLPHE M. - Restoration of the differentiated functions of serially passaged chondrocytes using staurosporine. In vitro Cell. Dev. Biol, 1997, 1071, 2690-2697.
15. MALLEIN-GERIN F., RUGGIERO F., GARRONE R. Proteoglycan core protein and type II collagen gene expressions are not correlated with cell shape changes during low density chondrocytes cultures. Differentiation, 1990, 43, 204-211.
16. NERLICH A.G., WIEST I., VON DER MARK K. Immunohistochemical analysis of interstitial collagens in cartilage of different stages of osteoarthrosis. Virchows Arch. B. Cell. Pathol., 1993, 63, 249-255.
17. HORTON W.A., MACHADO M.A., ELLARD J., CAMPBELL D., BARTLEY J., RAMIREZ F., VITALE E., LEE B. - Characterization of type II collagen(COL 2 A1) mutation identified in cultured chondrocytes from human hypochondrogenesis. Proc. Natl. Acad. Sci. USA., 1992, 89, 4583-4587.
18. LOHNERT J., BERNSMANN K., GOSSEN P., RUHNAU K., PHILIPPOUS S., FRITSCH K.G., FELDT S., SIODLA V., JOSIMOVIC-ALASEVIC O. - Aulologous chondrocyte transplantation (ACT) for the regeneration of articular cartilage in the knee. First results of a prospective study. Newsletter I. C. R. S., 1999, II, 20-21.
19. BINETTE F., MC QUAID D.P., HAUDENSCHILD D.R., YAEGER P.C., MC PHERSON J.M., TUBO R. Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro. J. Onhopaed. Res., 1998, 16(2), 207-216.
20. REDDI A.H. - Derived morphogenetic proteins and cartilage morphogenesis. Microsc. Res. Tech., 1998, 43 (2), 131-136.