Identification and characterization of differentially active pools of type IIα phosphatidylinositol 4-kinase activity in unstimulated A431 cells

Biochemical Journal

Volumn 376, Issue 2, 2003, Pages 497-503

  Waugh, Mark G ^a   Minogue, Shane ^a   Blumenkrantz, Deena ^a   Anderson, J Simon ^a   Hsuan, J Justin ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Detergent insoluble membrane; Low buoyant density membrane; Membrane microdomain; Phosphatidylinositol kinase; Phosphoinositide signalling; Subcellular fractionation

Indexed keywords

CATALYSIS; CELLS; CENTRIFUGATION; CLONING; DETERGENTS; ENZYME KINETICS;

CELL FUNCTIONS;

BIOCHEMISTRY;

ISOENZYME; PHOSPHATIDYLINOSITOL KINASE; PHOSPHATIDYLINOSITOL KINASE 2ALPHA; POLYPHOSPHOINOSITIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL FRACTIONATION; CELL FUNCTION; CELL MEMBRANE TRANSPORT; CELL ORGANELLE; CELL STRAIN; CELL STRAIN A431; CELL SURFACE; CELL TYPE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; DENSITY GRADIENT CENTRIFUGATION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; LIPOGENESIS; MAMMAL CELL; MOLECULAR CLONING; PH; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 4-KINASE; CELL LINE, TUMOR; CELL MEMBRANE; CENTRIFUGATION, DENSITY GRADIENT; HUMANS; PHOSPHATIDYLINOSITOL PHOSPHATES;

MAMMALIA;

EID: 0347517753     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031212     Document Type: Article

References (29)

1. Fruman, D. A., Meyers, R. E. and Cantley, L. C. (1998) Phosphoinositide kinases. Annu. Rev. Biochem. 67, 431-507
2. Hsuan, J. J., Minogue, S. and dos Santos, M. (1998) Phosphoinositide 4-and 5-kinases and the cellular roles of phosphatidylinositol 4,5-bisphosphate. Adv. Cancer Res. 74, 167-216
3. Gehrmann, T. and Heilmeyer, Jr, L. M. (1998) Phosphatidylinositol 4-kinases. Eur. J. Biochem. 253, 357-370
4. Levine, T. P. and Munro, S. (2002) Targeting of Golgi-specific pleckstrin homology domains involves both Ptdlns 4-kinase-dependent and -independent components. Curr. Biol. 12, 695-704
5. Duncan, M. C. and Payne, G. S. (2003) ENTH/ANTH domains expand to the Golgi. Trends Cell Biol. 13, 211-215
6. Mills, I. G., Praefcke, G. J., Vallis, Y., Peter, B. J., Olesen, L. E., Gallop, J. L., Butler, P. J., Evans, P. R. and McMahon, H. T. (2003) EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. J. Cell Biol. 160, 213-222
7. Heilmeyer, Jr, L. M., Vereb, Jr, G., Vereb, G., Kakuk, A. and Szivak, I. (2003) Mammalian phosphatidylinositol 4-kinases. IUBMB Life 55, 59-65
8. Wei, Y. J., Sun, H. Q., Yamamoto, M., Wlodarski, P., Kunii, K., Martinez, M., Barylko, B., Albanesi, J. P. and Yin, H. L. (2002) Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP. J. Biol. Chem. 277, 46586-46593
9. Waugh, M. G., Minogue, S., Anderson, J. S., Balinger, A., Blumenkrantz, D., Calnan, D. P., Cramer, R. and Hsuan, J. J. (2003) Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin- containing-protein-rich fraction of the endoplasmic reticulum. Biochem. J. 373, 57-63
10. Waugh, M. G., Lawson, D., Tan, S. K. and Hsuan, J. J. (1998) Phosphatidylinositol 4-phosphate synthesis in immunoisolated caveolae-like vesicles and low buoyant density non-caveolar membranes. J. Biol. Chem. 273, 17115-17121
11. Harlow, E. and Lane, D. (1988) Antibodies: a Laboratory Manual, Cold Spring Harbor Press, Cold Spring Harbor, NY
12. Gullick, W. J., Downward, J., Parker, P. J., Whittle, N., Kris, R., Schlessinger, J., Ullrich, A. and Waterfield, M. D. (1985) The structure and function of the epidermal growth factor receptor studied by using antisynthetic peptide antibodies. Proc. R. Soc. Lond. B Biol. Sci. 226, 127-134
13. Akhtar, R. A. and Wilmoth, T. L. (1992) Phorbol esters inhibit ionomycin-induced hydrolysis of phosphoinositides and phosphatidylcholine in bovine corneal epithelial cells. Curr. Eye Res. 11, 135-145
14. Hsuan, J. and Cockcroft, S. (2001) The PITP family of phosphatidylinositol transfer proteins. Genome Biol. 2, 3011.1-3011.8
15. Walker, D. H. and Pike, L. J. (1987) Phosphatidylinositol kinase is activated in membranes derived from cells treated with epidermal growth factor. Proc. Natl. Acad. Sci. U.S.A. 84, 7513-7517
16. Kauffmann, Z. A., Klinger, R., Endemann, G., Waterfield, M. D., Wetzker, R. and Hsuan, J. J. (1994) Regulation of human type II phosphatidylinositol kinase activity by epidermal growth factor-dependent phosphorylation and receptor association. J. Biol. Chem. 269, 31243-31251
17. Chatah, N. E. and Abrams, C. S. (2001) G-protein-coupled receptor activation induces the membrane translocation and activation of phosphatidylinositol-4-phosphate 5-kinase I alpha by a Rac-and Rho-dependent pathway. J. Biol. Chem. 276, 34059-34065
18. Park, S. J., Itoh, T. and Takenawa, T. (2001) Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli. J. Biol. Chem. 276, 4781-4787
19. Thomas, G. M., Cunningham, E., Fensome, A., Ball, A., Totty, N. F., Truong, O., Hsuan, J. J. and Cockcroft, S. (1993) An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signaling. Cell 74, 919-928
20. Kauffmann, Z. A., Thomas, G. M., Ball, A., Prosser, S., Cunningham, E., Cockcroft, S. and Hsuan, J. J. (1995) Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling. Science 268, 1188-1190
21. Waugh, M. G., Lawson, D. and Hsuan, J. J. (1999) Epidermal growth factor receptor activation is localized within low-buoyant density, non-caveolar membrane domains. Biochem. J. 337, 591-597
22. Sargiacomo, M., Sudol, M., Tang, Z. and Lisanti, M. P. (1993) Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J. Cell Biol. 122, 789-807
23. Roper, K., Corbeil, D. and Huttner, W. B. (2000) Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane. Nat. Cell Biol. 2, 582-592
24. Chun, M., Liyanage, U. K., Lisanti, M. P. and Lodish, H. F. (1994) Signal transaction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc. Natl. Acad. Sci. U.S.A. 91, 11728-11732
25. Andersson, K. and Hjorth, R. (1984) Isopycnic centrifugation of rat-liver microsomes in isoosmotic gradients of Percoll and release of microsomal material by low concentrations of sodium deoxycholate. Biochim. Biophys. Acta 770, 97-100
26. Pike, L. J. and Eakes, A. T. (1987) Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells. J. Biol. Chem. 262, 1644-1651
27. Olsson, H., Martinez, A. W. and Jergil, B. (1993) Phosphatidylcholine enhances the activity of rat liver type II phosphatidylinositol-kinase. FEBS Lett. 327, 332-336
28. Balla, A., Tuymetova, G., Barshishat, M., Geiszt, M. and Balla, T. (2002) Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments. J. Biol. Chem. 277, 20041-20050
29. Stephens, L., Jackson, T. R. and Hawkins, P. T. (1993) Activation of phosphatidylinositol 4,5-bisphosphate supply by agonists and non-hydrolysable GTP analogues. Biochem. J. 296, 481-488