-
2
-
-
0029011730
-
Toward improved anti-HIV chemotherapy: Therapeutic strategies for intervention with HIV infections
-
De Clercq, E. Toward improved anti-HIV chemotherapy: Therapeutic strategies for intervention with HIV infections. J. Med. Chem. 1995, 38, 2491-2517.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 2491-2517
-
-
De Clercq, E.1
-
3
-
-
0033615290
-
Primary HIV-1 resistance
-
Pomerantz, R. J. Primary HIV-1 resistance. J. Am. Med. Assoc. 1999, 282, 1177-1179.
-
(1999)
J. Am. Med. Assoc.
, vol.282
, pp. 1177-1179
-
-
Pomerantz, R.J.1
-
4
-
-
0034785773
-
Predicting the unpredictable: Transmission of drug-resistant HIV
-
Blower, S. M.; Aschenbach, A. N.; Gershengorn, H. B.; Kahn, J. O. Predicting the unpredictable: Transmission of drug-resistant HIV. Nature Medicine, 2001, 7, 1016-1020.
-
(2001)
Nature Medicine
, vol.7
, pp. 1016-1020
-
-
Blower, S.M.1
Aschenbach, A.N.2
Gershengorn, H.B.3
Kahn, J.O.4
-
5
-
-
0032577581
-
Chemokine receptors: Keys to AIDS pathogenesis?
-
Littman, D. R. Chemokine receptors: keys to AIDS pathogenesis? Cell 1998, 93, 677-680.
-
(1998)
Cell
, vol.93
, pp. 677-680
-
-
Littman, D.R.1
-
6
-
-
0033083950
-
Opportunities for novel therapeutic agents acting at chemokine receptors
-
Saunders, J.; Tarby, C. M. Opportunities for novel therapeutic agents acting at chemokine receptors. Drug Discovery Today 1999, 4, 80-92.
-
(1999)
Drug Discovery Today
, vol.4
, pp. 80-92
-
-
Saunders, J.1
Tarby, C.M.2
-
7
-
-
13044256383
-
A small molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
Baba, M.; Nishimura, O.; Kanzaki, N.; Okamoto, M.; Sawada, H.; Iizawa, Y.; Shiraishi, M.; Aramaki, Y.; Okonogi, K.; Ogawa, Y.; Meguro, K.; Fujino, M. A small molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. USA 1999, 96, 5698-5703.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
Shiraishi, M.7
Aramaki, Y.8
Okonogi, K.9
Ogawa, Y.10
Meguro, K.11
Fujino, M.12
-
8
-
-
0035846074
-
-
Palani, A.; Shapiro, S.; Clader, J. W.; Greenlee, W. J.; Cox, K.; Strizki, J.; Endres, M.; Baroudy, B. M. J. Med. Chem. 2001, 44, 3339-3342.
-
(2001)
Med. Chem.
, vol.44
, pp. 3339-3342
-
-
Palani, A.1
Shapiro, S.2
Clader, J.W.3
Greenlee, W.J.4
Cox, K.5
Strizki, J.6
Endres, M.7
Baroudy, B.M.J.8
-
9
-
-
0035931392
-
Antagonists of the human CCR5 receptor as anti-HIV -1-agents. Part 2: Structure-activity relationships for substituted 2-aryl-1-[N-(methyl)-N- (phenylsulfonyl)amino]-4-(piperidinyl-1-yl)butanes
-
Finke, P.E.; Meurer, L. C.; Oates, B.; Mills, S. G.; MacCoss, M.; Malkowitz, M.; Springer, M. S.; Daugherty, B. L.; Gould, S. L.; DeMartino, J. A.; Siciliano, S. J.; Carella, A.; Carver, G.; Holmes, K.; Danzeisen, R.; Hazuda, D.; Kessler, J.; Lineberger, J.; Miller, M.; Schleif, W. A.; Emini, E. A. Antagonists of the human CCR5 receptor as anti-HIV -1-agents. Part 2: Structure-activity relationships for substituted 2-aryl-1-[N-(methyl)-N- (phenylsulfonyl)amino]-4-(piperidinyl-1-yl)butanes. Bioorg. Med. Chem. Lett. 2001, 11, 265-270.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 265-270
-
-
Finke, P.E.1
Meurer, L.C.2
Oates, B.3
Mills, S.G.4
MacCoss, M.5
Malkowitz, M.6
Springer, M.S.7
Daugherty, B.L.8
Gould, S.L.9
DeMartino, J.A.10
Siciliano, S.J.11
Carella, A.12
Carver, G.13
Holmes, K.14
Danzeisen, R.15
Hazuda, D.16
Kessler, J.17
Lineberger, J.18
Miller, M.19
Schleif, W.A.20
Emini, E.A.21
more..
-
10
-
-
3242796997
-
Synthesis and anti-HIV activity of macrocyclic chemokine mimics
-
To be submitted
-
Balogh-Nair, V.; Brathwaite, C. E.; Chen, C. X.; Gonzalez, C. R.; Finberg, R. W. Synthesis and anti-HIV activity of macrocyclic chemokine mimics. To be submitted to J. Med. Chem; Reduction of HIV-1's infectivity by chemokine mimics. Presented at the Gordon Conference: Chemotherapy of AIDS, Ventura, CA, 1997.
-
J. Med. Chem.
-
-
Balogh-Nair, V.1
Brathwaite, C.E.2
Chen, C.X.3
Gonzalez, C.R.4
Finberg, R.W.5
-
11
-
-
3242796998
-
Reduction of HIV-1's infectivity by chemokine mimics
-
Ventura, CA
-
Balogh-Nair, V.; Brathwaite, C. E.; Chen, C. X.; Gonzalez, C. R.; Finberg, R. W. Synthesis and anti-HIV activity of macrocyclic chemokine mimics. To be submitted to J. Med. Chem; Reduction of HIV-1's infectivity by chemokine mimics. Presented at the Gordon Conference: Chemotherapy of AIDS, Ventura, CA, 1997.
-
(1997)
Gordon Conference: Chemotherapy of AIDS
-
-
-
12
-
-
0032496407
-
AIDS researchers negociate tricky slopes of science
-
Balter, M. AIDS researchers negociate tricky slopes of science. Science, 1998, 280, 825-826.
-
(1998)
Science
, vol.280
, pp. 825-826
-
-
Balter, M.1
-
13
-
-
0021333717
-
Pneumocystis carinii pneumonia: A comparison between patients with acquired immunodeficiency syndrome and patients with other immunodeficiencies
-
Kovacs, J. A.; Heimentz, J. W.; Macher, A. M.; Stover, D.; Murray, H. W.; Shelhamer, J.; Lane, H. C.; Urmarcher, C.; Honig, C.; Longo, D.; Parker, M. M.; Natanson, J.E.; Parillo, J. E.; Fauci, A. S.; Pizzo, P. A.; H. Masur, H. Pneumocystis carinii pneumonia: a comparison between patients with acquired immunodeficiency syndrome and patients with other immunodeficiencies, Ann. Int. Med. 1984, 100, 663-671.
-
(1984)
Ann. Int. Med.
, vol.100
, pp. 663-671
-
-
Kovacs, J.A.1
Heimentz, J.W.2
Macher, A.M.3
Stover, D.4
Murray, H.W.5
Shelhamer, J.6
Lane, H.C.7
Urmarcher, C.8
Honig, C.9
Longo, D.10
Parker, M.M.11
Natanson, J.E.12
Parillo, J.E.13
Fauci, A.S.14
Pizzo, P.A.15
Masur, H.H.16
-
14
-
-
0028568541
-
The emerging fungal threat
-
Sternberg, S. The emerging fungal threat. Science, 1994, 266, 1632-1634.
-
(1994)
Science
, vol.266
, pp. 1632-1634
-
-
Sternberg, S.1
-
15
-
-
0003984768
-
-
Medical Economics Data Production Company, Mont Vale, NJ
-
Physicians' Desk Reference, Medical Economics Data Production Company, Mont Vale, NJ, 2001; pp 1442-1446.
-
(2001)
Physicians' Desk Reference
, pp. 1442-1446
-
-
-
16
-
-
0027288837
-
DNA minor groove recognition properties of pentamidine and its analogs: A molecular modeling study
-
Greenidge, P. A.; Jenkins, T. C.; Neidle, S. DNA minor groove recognition properties of pentamidine and its analogs: A molecular modeling study. Mol. Pharmacol. 1993, 43, 982-988.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 982-988
-
-
Greenidge, P.A.1
Jenkins, T.C.2
Neidle, S.3
-
17
-
-
3242791297
-
Oxidoredox suppression of fungal infections by novel pharmacophores
-
Snyder, J. K.; Cooper, R., Eds.; Marcel Dekker Inc., Chapter 12
-
Balogh-Nair, V. Oxidoredox suppression of fungal infections by novel pharmacophores. In Advances in Bioorganic Chemistry. The Biology - Chemistry Interface. Snyder, J. K.; Cooper, R., Eds.; Marcel Dekker Inc., 1999, Chapter 12, pp 311-349.
-
(1999)
Advances in Bioorganic Chemistry. The Biology - Chemistry Interface
, pp. 311-349
-
-
Balogh-Nair, V.1
-
18
-
-
3242806983
-
Novel oxygenated macrocycles as oxygenase mimics
-
Brathwaite, C. E.; Chen, C. X.; Balogh-Nair, V. Novel oxygenated macrocycles as oxygenase mimics. Indian J. Chem. 1992, 31B, 810-812.
-
(1992)
Indian J. Chem.
, vol.31 B
, pp. 810-812
-
-
Brathwaite, C.E.1
Chen, C.X.2
Balogh-Nair, V.3
-
19
-
-
0032476812
-
Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors
-
Mammen, M.; Choi, S-K.; Whitesides, G. M. Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew. Chem. Int. Ed. 1998, 37, 2754-2794.
-
(1998)
Angew. Chem. Int. Ed.
, vol.37
, pp. 2754-2794
-
-
Mammen, M.1
Choi, S.-K.2
Whitesides, G.M.3
-
20
-
-
3242801668
-
Multivalency: Strength in numbers. Enormous affinity enhancements afforded by multivalent binding may have implications for drug design
-
October 9
-
Borman, S. Multivalency: Strength in numbers. Enormous affinity enhancements afforded by multivalent binding may have implications for drug design. C&N, 2000, October 9, pp 47-53.
-
(2000)
C&N
, pp. 47-53
-
-
Borman, S.1
-
21
-
-
0025883342
-
Nitric oxide: Physiology, pathophysiology, and pharmacology
-
Moncada, S.; Palmer, R. M. J.; Higgs, E. A. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacological Reviews 1991, 43, 109-142.
-
(1991)
Pharmacological Reviews
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.J.2
Higgs, E.A.3
-
22
-
-
0022653478
-
Macrophage-mediated fungistatis in vitro: Requirements for intracellular and extracellular cytotoxicity
-
Granger, D. L.; Perfect, J. R.; Durack, D. T. Macrophage-mediated fungistatis in vitro: Requirements for intracellular and extracellular cytotoxicity. J. Immunol. 1986, 136, 672-680.
-
(1986)
J. Immunol.
, vol.136
, pp. 672-680
-
-
Granger, D.L.1
Perfect, J.R.2
Durack, D.T.3
-
23
-
-
0025886986
-
Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis
-
Alspaugh, J.A. Granger, D. L. Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis. Infection and Immunity 1991, 59, 2291-2296.
-
(1991)
Infection and Immunity
, vol.59
, pp. 2291-2296
-
-
Alspaugh, J.A.1
Granger, D.L.2
-
24
-
-
0026470813
-
Bactericidal activity of peroxynitrite
-
Zhu, L.; Gunn, C.; Beckman, J. S. Bactericidal activity of peroxynitrite. Arch. Biochem. Biophys. 1992, 298, 452-457.
-
(1992)
Arch. Biochem. Biophys.
, vol.298
, pp. 452-457
-
-
Zhu, L.1
Gunn, C.2
Beckman, J.S.3
-
25
-
-
0026700522
-
Evidence for reactive nitrogen intermediates in killing of Staphylococci by human neutrophil cytoplasts
-
Malawista, S. E.; Montgomery, R. R.; Van Blaricom, G. Evidence for reactive nitrogen intermediates in killing of Staphylococci by human neutrophil cytoplasts. J. Clin. Invest. 1992, 90, 631-636.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 631-636
-
-
Malawista, S.E.1
Montgomery, R.R.2
Van Blaricom, G.3
-
26
-
-
0027967694
-
Ras-effector homologue region on Rac regulates protein associations in the neutrophil respiratory burst oxidase complex
-
Freman, J. L. R.; Kreck, M. L.; Uhlinger, D. J.; Lambeth, J. D. Ras-effector homologue region on Rac regulates protein associations in the neutrophil respiratory burst oxidase complex. Biochemistry 1994, 33, 13431-13435.
-
(1994)
Biochemistry
, vol.33
, pp. 13431-13435
-
-
Freman, J.L.R.1
Kreck, M.L.2
Uhlinger, D.J.3
Lambeth, J.D.4
-
27
-
-
3242785988
-
Methoden zur herstellung und umwandlung von oxaziridinen
-
Houben, J.; Weyl, Th.; Muller, E., Eds. Thieme: Stuttgart
-
Rundel, W. Methoden zur Herstellung und Umwandlung von Oxaziridinen, In Methoden der Organischen Chemie. Houben, J.; Weyl, Th.; Muller, E., Eds. Thieme: Stuttgart, 1988; band X/4. p 449.
-
(1988)
Methoden der Organischen Chemie
, vol.10
, Issue.4
, pp. 449
-
-
Rundel, W.1
-
28
-
-
0346654496
-
13CH coupling constants in oxaziridines
-
13CH coupling constants in oxaziridines. J. Am. Chem. Soc. 1972, 94, 8501-854.
-
(1972)
J. Am. Chem. Soc.
, vol.94
, pp. 8501-8854
-
-
Jennings, W.B.1
Boyd, D.R.2
Watson, C.G.3
Becker, E.D.4
Bradley, R.B.5
Jerina, D.M.6
-
29
-
-
84989030959
-
Multinuclear magnetic resonance study of oxaziridines
-
Cudic, M.; Herrman, R. Multinuclear magnetic resonance study of oxaziridines. Magn. Reson. Chem. 1993, 31, 461-467.
-
(1993)
Magn. Reson. Chem.
, vol.31
, pp. 461-467
-
-
Cudic, M.1
Herrman, R.2
-
30
-
-
3242745543
-
-
Wolff, M. E., Ed.; Wiley: New York, Chapter 1
-
Burger's Medicinal Chemistry and Drug Discovery. Volume 1. Principles and Practice. Wolff, M. E., Ed.; Wiley: New York, 1995; Vol. 1, Chapter 1, p 15.
-
(1995)
Burger's Medicinal Chemistry and Drug Discovery. Volume 1. Principles and Practice
, vol.1
, pp. 15
-
-
-
31
-
-
0028061291
-
Albendazole inhibits Pneumocystis carinii proliferation in inoculated immunosuppressed mice
-
Bartlett, M. S.; Edlind, T. D.; Lee, C-H.; Dean, R.; Queener, S. F.; Shaw, M. M.; Smith, J. W. Albendazole inhibits Pneumocystis carinii proliferation in inoculated immunosuppressed mice. Antimicrob. Agents & Chemother. 1994, 38, 1834-1837.
-
(1994)
Antimicrob. Agents & Chemother.
, vol.38
, pp. 1834-1837
-
-
Bartlett, M.S.1
Edlind, T.D.2
Lee, C.-H.3
Dean, R.4
Queener, S.F.5
Shaw, M.M.6
Smith, J.W.7
-
32
-
-
0001494674
-
Synthesis of a three-helix bundle protein by reductive amination
-
Tahmasebbi, D. C.; Sasaki, T. Synthesis of a three-helix bundle protein by reductive amination. J. Org. Chem. 1994, 59, 728-731.
-
(1994)
J. Org. Chem.
, vol.59
, pp. 728-731
-
-
Tahmasebbi, D.C.1
Sasaki, T.2
-
33
-
-
3242744779
-
-
Ph.D. thesis, The City University of New York
-
Peng, L., Ph.D. thesis, The City University of New York, 1999.
-
(1999)
-
-
Peng, L.1
|