-
1
-
-
0033615525
-
Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains
-
Aplin AE, Short SM, Juliano RL. Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains. J Biol Chem 274:31223-31228;1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 31223-31228
-
-
Aplin, A.E.1
Short, S.M.2
Juliano, R.L.3
-
2
-
-
0035897407
-
Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1
-
Aplin AE, Stewart SA, Assoian RK, Juliano RL. Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. J Cell Biol 153:273-281;2001.
-
(2001)
J Cell Biol
, vol.153
, pp. 273-281
-
-
Aplin, A.E.1
Stewart, S.A.2
Assoian, R.K.3
Juliano, R.L.4
-
3
-
-
0035409351
-
Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: Insights into the signaling pathway
-
Banfi C, Eriksson P, Giandomenico G, Mussoni L, Sironi L, Hamsten A, Tremoli E. Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: Insights into the signaling pathway. Diabetes 50:1522-1530; 2001.
-
(2001)
Diabetes
, vol.50
, pp. 1522-1530
-
-
Banfi, C.1
Eriksson, P.2
Giandomenico, G.3
Mussoni, L.4
Sironi, L.5
Hamsten, A.6
Tremoli, E.7
-
4
-
-
0032748523
-
Proteolysis, cell adhesion, chemotaxis, and invasiveness are regulated by the u-PA-u-PAR-PAI-1 system
-
Blasi F. Proteolysis, cell adhesion, chemotaxis, and invasiveness are regulated by the u-PA-u-PAR-PAI-1 system. Thromb Haemost 82:298-304;1999.
-
(1999)
Thromb Haemost
, vol.82
, pp. 298-304
-
-
Blasi, F.1
-
5
-
-
0026608787
-
Nuclear localization and regulation of ERK- and RSK-encoded protein kinases
-
Chen RH, Sarnecki C, Blenis J. Nuclear localization and regulation of ERK- and RSK-encoded protein kinases. Mol Cell Biol 12:915-927;1992.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 915-927
-
-
Chen, R.H.1
Sarnecki, C.2
Blenis, J.3
-
6
-
-
0029589630
-
Alpha-2 macroglobulin receptor/Ldl receptor-related protein (Lrp)-dependent internalization of the urokinase receptor
-
Conese M, Nykjaer A, Petersen CM, Cremona O, Pardi R, Andreasen PA, Gliemann J, Christensen EI, Blasi F. Alpha-2 macroglobulin receptor/Ldl receptor-related protein (Lrp)-dependent internalization of the urokinase receptor. J Cell Biol 131:1609-1622;1995.
-
(1995)
J Cell Biol
, vol.131
, pp. 1609-1622
-
-
Conese, M.1
Nykjaer, A.2
Petersen, C.M.3
Cremona, O.4
Pardi, R.5
Andreasen, P.A.6
Gliemann, J.7
Christensen, E.I.8
Blasi, F.9
-
7
-
-
0025273735
-
Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
-
Cubellis MV, Wun TC, Blasi F. Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 9:1079-1085;1990.
-
(1990)
EMBO J
, vol.9
, pp. 1079-1085
-
-
Cubellis, M.V.1
Wun, T.C.2
Blasi, F.3
-
8
-
-
0029816265
-
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
-
Deng G, Curriden SA, Wang S, Rosenberg S, Loskutoff DJ. Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J Cell Biol 134:1563-1571;1996.
-
(1996)
J Cell Biol
, vol.134
, pp. 1563-1571
-
-
Deng, G.1
Curriden, S.A.2
Wang, S.3
Rosenberg, S.4
Loskutoff, D.J.5
-
10
-
-
0026695645
-
Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter
-
Gille HA, Sharrocks D, Shaw PE. Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358:414-417;1992.
-
(1992)
Nature
, vol.358
, pp. 414-417
-
-
Gille, H.A.1
Sharrocks, D.2
Shaw, P.E.3
-
11
-
-
0035816732
-
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22 (phox)-containing NADPH oxidase
-
Gorlach A, Diebold I, Schini-Kerth VB, Berchner-Pfannschmidt U, Roth U, Brandes RP, Kietzmann T, Busse R. Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22 (phox)-containing NADPH oxidase. Circ Res 89:47-54;2001.
-
(2001)
Circ Res
, vol.89
, pp. 47-54
-
-
Gorlach, A.1
Diebold, I.2
Schini-Kerth, V.B.3
Berchner-Pfannschmidt, U.4
Roth, U.5
Brandes, R.P.6
Kietzmann, T.7
Busse, R.8
-
12
-
-
0029015774
-
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
-
Hill CS, Wynne J, Treisman R. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81: 1159-1170;1995.
-
(1995)
Cell
, vol.81
, pp. 1159-1170
-
-
Hill, C.S.1
Wynne, J.2
Treisman, R.3
-
14
-
-
0029873910
-
The urokinase receptor is a major vitronectin-binding protein on endothelial cells
-
Kanse SM, Kost C, Wilhelm OG, Andreasen PA, Preissner KT. The urokinase receptor is a major vitronectin-binding protein on endothelial cells. Exp Cell Res 224:344-353;1996.
-
(1996)
Exp Cell Res
, vol.224
, pp. 344-353
-
-
Kanse, S.M.1
Kost, C.2
Wilhelm, O.G.3
Andreasen, P.A.4
Preissner, K.T.5
-
15
-
-
0000124642
-
Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation
-
Kjoller L, Kanse SM, Kirkegaard T, Rodenburg KW, Ronne E, Goodman SL, Preissner KT, Ossowski L, Andreasen PA. Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation. Exp Cell Res 232:420-429;1997.
-
(1997)
Exp Cell Res
, vol.232
, pp. 420-429
-
-
Kjoller, L.1
Kanse, S.M.2
Kirkegaard, T.3
Rodenburg, K.W.4
Ronne, E.5
Goodman, S.L.6
Preissner, K.T.7
Ossowski, L.8
Andreasen, P.A.9
-
16
-
-
0036226356
-
Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats
-
Kobayashi N, Nakano S, Mita S, Kobayashi T, Honda T, Tsubokou Y, Matsuoka H. Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats. J Pharmacol Exp Ther 301:459-466;2002.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 459-466
-
-
Kobayashi, N.1
Nakano, S.2
Mita, S.3
Kobayashi, T.4
Honda, T.5
Tsubokou, Y.6
Matsuoka, H.7
-
17
-
-
0028239101
-
Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2
-
Kortenjann M, Thomae O, Shaw PE. Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2. Mol Cell Biol 14:4815-4824;1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4815-4824
-
-
Kortenjann, M.1
Thomae, O.2
Shaw, P.E.3
-
18
-
-
0034747099
-
TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion
-
Kutz SM, Hordines J, McKeown-Longo PJ, Higgins PJ. TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion. J Cell Sci 114:3905-3914; 2001.
-
(2001)
J Cell Sci
, vol.114
, pp. 3905-3914
-
-
Kutz, S.M.1
Hordines, J.2
McKeown-Longo, P.J.3
Higgins, P.J.4
-
19
-
-
0034014726
-
Plasminogen activator inhibitor 1 may promote tumour growth through inhibition of apoptosis
-
Kwaan HC, Wang J, Svoboda K, Declerck PJ. Plasminogen activator inhibitor 1 may promote tumour growth through inhibition of apoptosis. Br J Cancer 82:1702-1708;2000.
-
(2000)
Br J Cancer
, vol.82
, pp. 1702-1708
-
-
Kwaan, H.C.1
Wang, J.2
Svoboda, K.3
Declerck, P.J.4
-
20
-
-
0036083189
-
Cell adhesion regulates the plasminogen activator inhibitor-1 gene expression in anchorage-dependent cells
-
Lee CC, Shyu KG, Lin S, Wang BW, Liu YC, Chang H. Cell adhesion regulates the plasminogen activator inhibitor-1 gene expression in anchorage-dependent cells. Biochem Biophys Res Commun 291:185-190;2002.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 185-190
-
-
Lee, C.C.1
Shyu, K.G.2
Lin, S.3
Wang, B.W.4
Liu, Y.C.5
Chang, H.6
-
21
-
-
0027283659
-
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45 mapkk) in fibro-blasts
-
Lenormand P, Sardet C, Pages G, L'Allemain G, Brunet A, Pouyssegur J. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45 mapkk) in fibro-blasts. J Cell Biol 122:1079-1088;1993.
-
(1993)
J Cell Biol
, vol.122
, pp. 1079-1088
-
-
Lenormand, P.1
Sardet, C.2
Pages, G.3
L'Allemain, G.4
Brunet, A.5
Pouyssegur, J.6
-
22
-
-
0034802324
-
GL331 induces down-regulation of cyclin D1 expression via enhanced proteolysis and repressed transcription
-
Lin S, Huang HC, Chen LL, Lee CC, Huang TS. GL331 induces down-regulation of cyclin D1 expression via enhanced proteolysis and repressed transcription. Mol Pharmacol 60: 768-774;2001.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 768-774
-
-
Lin, S.1
Huang, H.C.2
Chen, L.L.3
Lee, C.C.4
Huang, T.S.5
-
23
-
-
0031003237
-
Cell anchorage permits efficient signal transduction between Ras and its downstream kinases
-
Lin TH, Chen Q, Howe A, Julinano RL. Cell anchorage permits efficient signal transduction between Ras and its downstream kinases. J Biol Chem 272:8849-8852;1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 8849-8852
-
-
Lin, T.H.1
Chen, Q.2
Howe, A.3
Julinano, R.L.4
-
25
-
-
0033013861
-
Activation of plasminogen activator inhibitor-1 synthesis by phorbol esters in human promyelocyte HL-60 - Roles of PKCβ and MAPK p42
-
Lopez S, Peiretti F, Morange P, Laouar A, Fossat C, Bonardo B, Huberman E, Juhan-Vague I, Nalbone G. Activation of plasminogen activator inhibitor-1 synthesis by phorbol esters in human promyelocyte HL-60 - Roles of PKCβ and MAPK p42. Thromb Haemost 81:415-422;1999.
-
(1999)
Thromb Haemost
, vol.81
, pp. 415-422
-
-
Lopez, S.1
Peiretti, F.2
Morange, P.3
Laouar, A.4
Fossat, C.5
Bonardo, B.6
Huberman, E.7
Juhan-Vague, I.8
Nalbone, G.9
-
26
-
-
0024568021
-
-
Philadelphia, Saunders
-
Loskutoff KJ, Sawdey M, Mimuro J, Coller B. Progress in Hemostasis and Thrombosis, ed 9. Philadelphia, Saunders, 87-115;1989.
-
(1989)
Progress in Hemostasis and Thrombosis, Ed 9
, pp. 87-115
-
-
Loskutoff, K.J.1
Sawdey, M.2
Mimuro, J.3
Coller, B.4
-
28
-
-
0027297647
-
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
-
Marais R, Wynne J, Treisman R. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-393;1993.
-
(1993)
Cell
, vol.73
, pp. 381-393
-
-
Marais, R.1
Wynne, J.2
Treisman, R.3
-
29
-
-
0030453194
-
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
-
Miyamoto S, Teramoto H, Gutkind JS, Yamada KM. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors. J Cell Biol 135:1633-1642;1996.
-
(1996)
J Cell Biol
, vol.135
, pp. 1633-1642
-
-
Miyamoto, S.1
Teramoto, H.2
Gutkind, J.S.3
Yamada, K.M.4
-
30
-
-
0030926412
-
Recycling of the urokinase receptor upon internalization of the uPA:Serpin complexes
-
Nykjaer A, Conese M, Christensen EI, Olson D, Cremona O, Gliemann J, Blasi F. Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes. EMBO J 16: 2610-2620;1997.
-
(1997)
EMBO J
, vol.16
, pp. 2610-2620
-
-
Nykjaer, A.1
Conese, M.2
Christensen, E.I.3
Olson, D.4
Cremona, O.5
Gliemann, J.6
Blasi, F.7
-
31
-
-
0037175016
-
Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells
-
Palmier D, Lee JW, Juliano RL, Church FC. Plasminogen activator inhibitor-1 and -3 increase cell adhesion and motility of MDA-MB-435 breast cancer cells. J Biol Chem 277: 40950-40957;2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 40950-40957
-
-
Palmier, D.1
Lee, J.W.2
Juliano, R.L.3
Church, F.C.4
-
32
-
-
0030766846
-
Growth factor activation of MAP kinase requires cell adhesion
-
Renshaw MW, Ren XD, Schwartz MA: Growth factor activation of MAP kinase requires cell adhesion. EMBO J 16:5592-5599; 1997.
-
(1997)
EMBO J
, vol.16
, pp. 5592-5599
-
-
Renshaw, M.W.1
Ren, X.D.2
Schwartz, M.A.3
-
33
-
-
0032725554
-
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1(HIF-1) and enhance the transcriptional activity of HIF-1
-
Richard DE, Berra E, Gothie E, Roux D, Pouyssegur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1(HIF-1) and enhance the transcriptional activity of HIF-1. J Biol Chem 274: 32631-32637;1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 32631-32637
-
-
Richard, D.E.1
Berra, E.2
Gothie, E.3
Roux, D.4
Pouyssegur, J.5
-
34
-
-
0029918347
-
Complex regulation of plasminogen activator inhibitor type-1 (PAI-1) gene expression by serum and substrate adhesion
-
Ryan MP, Kutz SM, Higgins PJ. Complex regulation of plasminogen activator inhibitor type-1 (PAI-1) gene expression by serum and substrate adhesion. Biochem J 314:1041-1046; 1996.
-
(1996)
Biochem J
, vol.314
, pp. 1041-1046
-
-
Ryan, M.P.1
Kutz, S.M.2
Higgins, P.J.3
-
37
-
-
0034724667
-
Integrins regulate the linkage between upstream and downstream events in G-protein-coupled receptor signaling to mitogen-activated protein kinase
-
Short SM, Boyer JL, Juliano RL. Integrins regulate the linkage between upstream and downstream events in G-protein-coupled receptor signaling to mitogen-activated protein kinase. J Biol Chem 275:12970-12977;2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 12970-12977
-
-
Short, S.M.1
Boyer, J.L.2
Juliano, R.L.3
-
38
-
-
0023130521
-
Plasminogen activator inhibitors
-
Sprengers ED, Kluft C. Plasminogen activator inhibitors. Blood 69:381-387;1987.
-
(1987)
Blood
, vol.69
, pp. 381-387
-
-
Sprengers, E.D.1
Kluft, C.2
-
39
-
-
0029745109
-
The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin
-
Stefansson S, Lawrence DA. The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin. Nature 383:441-443;1996.
-
(1996)
Nature
, vol.383
, pp. 441-443
-
-
Stefansson, S.1
Lawrence, D.A.2
-
40
-
-
0035041566
-
Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression
-
Takeda K, Ichiki T, Tokunou T, Iino N, Fujii S, Kitabatake A, Shimokawa H, Takeshita A. Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression. Arterioscler Thromb Vasc Biol 21:868-873;2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 868-873
-
-
Takeda, K.1
Ichiki, T.2
Tokunou, T.3
Iino, N.4
Fujii, S.5
Kitabatake, A.6
Shimokawa, H.7
Takeshita, A.8
-
41
-
-
0037085780
-
Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1
-
Fink T, Kazlauskas A, Poellinger L, Ebbesen P, Zachar V. Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1. Blood 99:2077-2083;2002.
-
(2002)
Blood
, vol.99
, pp. 2077-2083
-
-
Fink, T.1
Kazlauskas, A.2
Poellinger, L.3
Ebbesen, P.4
Zachar, V.5
-
42
-
-
0035911155
-
Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth
-
Webb DJ, Thomas KS, Gonias SL. Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth. J Cell Biol 152:741-751;2001.
-
(2001)
J Cell Biol
, vol.152
, pp. 741-751
-
-
Webb, D.J.1
Thomas, K.S.2
Gonias, S.L.3
-
43
-
-
0029125757
-
Integration of MAP kinase signal transduction pathways at the serum response element
-
Whitmarsh AJ, Shore P, Sharrocks AD, Davis RJ. Integration of MAP kinase signal transduction pathways at the serum response element. Science 269:403-407;1995.
-
(1995)
Science
, vol.269
, pp. 403-407
-
-
Whitmarsh, A.J.1
Shore, P.2
Sharrocks, A.D.3
Davis, R.J.4
|