Surface-modified poly(lactide-co-glycolide) nanospheres for targeted bone imaging with enhanced labeling and delivery of radioisotope

Journal of Biomedical Materials Research - Part A

Volumn 67, Issue 3, 2003, Pages 751-760

  Park, Yoon Jeong ^a   Nah, Sook Hee ^b   Lee, Jue Yeon ^b   Jeong, Jae Min ^c   Chung, Jun Key ^c   Lee, Myung Chul ^c   Yang, Victor C ^a   Lee, Seung Jin ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Ewha Womans University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Bone and bone marrow targeting; Imaging; Poloxamer 407; Polymer nanospheres; Radioisotope carrier

Indexed keywords

BIODEGRADATION; BLOOD; DRUG DOSAGE; LABELING; RADIOISOTOPES; RADIOLOGY; SURFACE TREATMENT;

NANOSPHERES;

BONE;

COPOLYMER; DICYCLOHEXYLCARBODIIMIDE; HYDROXYL GROUP; HYDROXYPHENYLPROPIONIC ACID; IODINE 125; LIGAND; NANOPARTICLE; POLOXAMER; POLYGLACTIN; PROPIONIC ACID DERIVATIVE; RADIOISOTOPE; TECHNETIUM TIN COLLOID TC 99M; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BODY DISTRIBUTION; BONE; CHEMICAL MODIFICATION; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; DRUG TARGETING; ISOTOPE LABELING; LIVER; MOLECULAR SIZE; MOUSE; NONHUMAN; SERUM; SPLEEN;

EID: 0347385155     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.10147     Document Type: Article

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