The indirect negative inotropic effect of carbachol in β1-adrenoceptor antagonist-treated human right atria

European Journal of Pharmacology

Volumn 458, Issue 1-2, 2003, Pages 163-170

  Wangemann, Thekla ^a   Giessler, Christine ^a   Willmy Matthes, Pia ^a   Silber, Ralf Edgar ^a   Brodde, Otto Erich ^a,b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

Author keywords

1 Adrenoceptor antagonist; Atrium human right; Carbachol; Indirect; Muscarinic M2 receptor; Negative inotropic effect

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ACETYLSALICYLIC ACID; ADENYLATE CYCLASE; ADRENERGIC RECEPTOR AFFECTING AGENT; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIBIOTIC AGENT; BETA 1 ADRENERGIC RECEPTOR; BISOPROLOL; CALCIUM CHANNEL BLOCKING AGENT; CARBACHOL; CYCLIC AMP; DIGITALIS GLYCOSIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HEPARIN; HISTAMINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METOPROLOL; NITRIC ACID DERIVATIVE; NORADRENALIN; SEROTONIN; TERBUTALINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; HEART RIGHT ATRIUM; HUMAN; HUMAN TISSUE; INOTROPISM; ISOLATED HEART; MALE; PRIORITY JOURNAL;

ADENYLATE CYCLASE; ADRENERGIC ANTAGONISTS; ADRENERGIC BETA-AGONISTS; AGED; CARBACHOL; CARDIOTONIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; HEART; HEART ATRIA; HISTAMINE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; NOREPINEPHRINE; RECEPTORS, ADRENERGIC, BETA-1; SEROTONIN; TERBUTALINE;

EID: 0347297443     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02763-2     Document Type: Article

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