Suppressive effects of Perilla frutescents on IgA nephropathy in HIGA mice

Nephrology Dialysis Transplantation

Volumn 18, Issue 3, 2003, Pages 484-490

  Makino, Toshiaki ^a   Ono, Takahiko ^a   Matsuyama, Kotone ^a   Nogaki, Fumiaki ^a   Miyawaki, Shigeki ^a   Honda, Gisho ^a   Muso, Eri ^b  

^a KYOTO UNIVERSITY   (Japan)

^b Kitano Hospital   (Japan)

Author keywords

HIGA mice; IgA nephropathy; Intestinal mucosal immune system; Perilla frutescens; Rosmarinic acid

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; PERILLA EXTRACT; PLANT EXTRACT; ROSMARINIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG POTENTIATION; FEMALE; GLOMERULUS; HERBAL MEDICINE; HISTOPATHOLOGY; IMMUNE SYSTEM; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEPOSITION; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE CELL; INTESTINE MUCOSA; JAPAN; KIDNEY PARENCHYMA; MESANGIUM CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PERILLA; PEYER PATCH; PRIORITY JOURNAL; PROTEINURIA; SCORING SYSTEM; SPLEEN CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CINNAMATES; DEPSIDES; DIGESTIVE SYSTEM; DISEASE MODELS, ANIMAL; FEMALE; GLOMERULONEPHRITIS, IGA; IMMUNOGLOBULIN A; MICE; PERILLA FRUTESCENS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RANDOM ALLOCATION;

EID: 0347297126     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/18.3.484     Document Type: Article

References (21)

1. Emancipator SN, Lamm ME. IgA nephropathy: pathogenesis of the most common form of glomerulonephritis. Lab Invest 1989; 60: 168-183
2. Chauveau D, Droz D. Follow-up evaluation of the first patients with IgA nephropathy described at Necker Hospital. In: Béné MC, Faure G, Kesseler M, eds. IgA Nephropathy: The 25th Year Contrib Nephrol. Karger, Basel: 1993: 1-5
3. Ono T, Kanatsu K, Sekita K et al. Effect of long term administration of TJ-96 in IgA nephropathy, relationship with upper respiratory tract infection. Int Symp IgA Nephropathy 1992; 25: T08
4. Ono T, Yashiro M, Oyama A, Yoshida H, Muso E, Sasayama S. Inhibitory effect of the herbal medicine Saiboku-to on the proliferation of cultured murine mesangial cells. Nephrology 1998; 4: 367-372
5. Makino T, Ono T, Muso E, Honda G, Sasayama S. Suppressive effects of Perilla frutescens on spontaneous IgA nephropathy in ddY mice. Nephron 1999; 83: 40-46
6. Makino T, Ito M, Kiuchi F, Ono T, Muso E, Honda G. Inhibitory effect of decoction of Perilla frutescens on cultured murine mesangial cell proliferation and quantitative analysis of its active constituents. Planta Med 2001; 67: 24-28
7. Makino T, Ono T, Muso E, Honda G. Inhibitory effect of Perilla frutescens and its phenolic constituents on cultured murine mesangial cell proliferation. Planta Med 1998; 64: 541-545
8. Makino T, Ono T, Muso E, Yoshida H, Honda G, Sasayama S. Inhibitory effects of rosmarinic acid on the proliferation of cultured murine mesangial cells. Nephrol Dial Transplant 2000; 15: 1140-1145
9. Muso E, Takeuchi E, Shimada T, Yashiro M, Sugiyama T, Kawai C. Pathogenic role of polyclonal and polymeric IgA in murine model of mesangial proliferative glomerulonephritis with IgA deposition. J Clin Exp Immunol 1991; 84: 459-465
10. Miyawaki S, Muso E, Takeuchi E et al. Selective breeding for high serum IgA levels from noninbred ddY mice: isolation of a strain with an early onset of glomerular IgA deposition. Nephron 1997; 76: 201-207
11. Muso E, Yoshida H, Takeuchi E et al. Enhanced production of glomerular extracellular matrix in a new mouse strain of high serum IgA ddY mice. Kidney Int 1996; 50: 1946-1957
12. Kamata T, Nogaki F, Fagarasan S et al. Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA. J Immunol 2000; 165: 1387-1394
13. Fukui H, Yazaki K, Tabata M. Two phenolic acids from Lithospermum erythrorhizon cell suspension cultures. Phytochemistry 1984; 23: 2398-2399
14. Husband AJ, Gowans JL. The origin and antigen-dependent distribution of IgA containing cells in the intestine. J Exp Med 1978; 148: 1146-1160
15. Mestrecky J, McGhee JR. Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response. Adv Immunol 1987; 40: 153-245
16. Langkamp-Henken B, Glezer JA, Kudsk KA. Immunologic structure and function of the gastrointestinal tract. Nutr Clin Pract 1992; 7: 100-108
17. Yan D, Zhou HR, Brooks KH, Pestka JJ. Role of macrophages in elevated IgA and IL-6 production by Peyer's patch cultures following acute oral vomitoxin exposure. Toxicol Appl Pharmacol 1998; 148: 261-273
18. Kitazato Institute. Pharmaceuticals containing interferon inducers from Perilla frutescens. Japanese Patent Bulletin 1987; JP62: 5407.
19. Asada M, Fukumori Y, Inoue M et al. Glycoprotein derived from the hot water extract of mint plant, Perilla frutescens Britton. J Agri Food Chem 1999; 47: 468-472
20. Nogaki F, Muso E, Kobayashi I et al. Interleukin 12 induces crescentic glomerular lesions in a high IgA strain of ddY mice, independently of changes in IgA deposition. Nephrol Dial Transplant 2000; 15: 1146-1154
21. Ishihara T, Okamoto I, Masaki N et al. Inhibition of antigen-specific T helper type 2 responses by Perilla frutescens extract. Allergy 1999; 48: 443-450