Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer risk

Journal of Urology

Volumn 171, Issue 2 I, 2004, Pages 652-655

  Visvanathan, Kala ^a   Helzlsouer, Kathy J ^a   Boorman, David W ^b   Strickland, Paul T ^a   Hoffman, Sandy C ^a   Comstock, George W ^a   O'Brien, Thomas G ^b   Guo, Yongjun ^b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Ornithine decarboxylase; Polymorphism (genetics); Prostate; Prostatic neoplasms; Receptors, androgen

Indexed keywords

ADENINE; ANDROGEN; ANDROGEN RECEPTOR; GUANINE; NICOTINE; ORNITHINE DECARBOXYLASE;

ADULT; AGED; ARTICLE; CANCER RISK; CONTROLLED STUDY; DNA POLYMORPHISM; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; SMOKING; TRANSCRIPTION INITIATION; TUMOR GROWTH;

EID: 0347129589     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000108384.74718.73     Document Type: Article

References (20)

1. Janne, J., Poso, H. and Raina, A.: Polyamines in rapid growth and cancer. Biochim Biophys Acta, 473: 241, 1978
2. O'Brien, T. G., Megosh, L. C., Gilliard, G. and Soler, A. P.: Ornithine decarboxylase over expression is a sufficient condition for tumor promotion in mouse skin. Cancer Res, 57: 2630, 1997
3. Mohan, R. R., Challa, A., Gupta, S., Bostwick, D. G., Ahmad, N., Agarwal, R. et al: Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans. Clin Cancer Res, 5: 143, 1999
4. Gupta, S., Ahmed, N., Marengo, S. R., MacLennan, G. T., Greenberg, N. M. and Mukhtar, H.: Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice. Cancer Res, 60: 5125, 2000
5. Guo, Y., Harris, R. B., Rosson, D., Boorman, D. and O'Brien, T. G.: Functional analysis of human ornithine decarboxylase alleles. Cancer Res, 60: 6314, 2000
6. Betts, A. M., Waite, I., Neal, D. E. and Robson, C. N.: Androgen regulation of ornithine decarboxylase in human prostatic cells identified using differential display. FEBS Lett, 405: 328, 1997
7. Janne, O., Crozat, A., Palvimo, J. and Eisenberg, L.: Androgen-regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase genes. J Steroid Biochem Mol Biol, 40: 307, 1991
8. Silva, I. S., Morsch, D. M., Urnauer, L. and Spritzer, P. M.: Androgen-induced cell growth and c-myc expression in human non-transformed epithelial prostatic cells in primary culture. Endocr Res, 27: 153, 2001
9. Chamberlain, N. L., Driver, E. D. and Miesfeld, R. L.: The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res, 22: 3181, 1994
10. Beilin, J., Ball, E. M., Favaloro, J. M. and Zajac, J. D.: Effect of the androgen receptor CAG repeat polymorphism on transcriptional activity: specificity in prostate and non-prostate cell lines. J Mol Endocrinol, 25: 85, 2000
11. Giovannucci, E.: Is the androgen receptor CAG repeat length significant for prostate cancer? Cancer Epidemiol Biomarkers Prev, 11: 985, 2002
12. Nelson, K. A. and Witte, J. S.: Androgen receptor CAG repeats and prostate cancer. Am J Epidemiol, 155: 883, 2002
13. Chen, Y., Megosh, L. C., Gilmour, S. K., Sawicki, J. A. and O'Brien, T. G.: K6/ODC transgenic mice as a sensitive model for carcinogen identification. Toxicol Lett, 116: 27, 2000
14. Olson, J. W. and Crooks, P. A.: Effect of nicotine and N′-nitrosonornicotine on rat lung and trachea ornithine decarboxylase activity. Carcinogenesis, 6: 1517, 1985
15. Levi, F. and La Vecchia, C.: Tobacco smoking and prostate cancer: time for an appraisal. Ann Oncol, 12: 733, 2001
16. Fleming, I. D., Cooper, J. S., Hensen, D. E., Hutter, R. V. P., Kennedy, B. J., Murphy, G. P. et al: AJCC Cancer Staging Manual, 5th ed. Philadelphia: Lippincott-Raven Publishers, 1997
17. Boorman, D. W., Guo, Y., Visvanathan, K., Helzlsouer, K. and O'Brien, T. G.: Automated fragment analysis method for determining androgen receptor CAG repeat length. Biotechniques, 33: 140, 2002
18. Dai, W. S., Gutai, J. P., Kuller, L. H. and Cauley, J. A.: Cigarette smoking and serum sex hormones in men. Am J Epidemiol, 128: 796, 1988
19. Hopkins, J. M. and Evans, H. J.: Cigarette smoke-induced DNA damage and lung cancer risk. Nature, 283: 388, 1980
20. Smith, E. and Hagopian, C.: Uptake and secretion of carcinogenic chemicals by the dog and rat prostate. In: The Prostate Cell: Structure and Function. Edited by A. A. S. G. P. Murphy and J. P. Karr. New York: Alan R. Liss, pp. 131-163, 1981