Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy

Sleep

Volumn 26, Issue 7, 2003, Pages 809-810

  Hecht, Marketa ^a   Lin, Ling ^a   Kushida, Clete A ^a   Umetsu, Dale T ^a   Taheri, Shahrad ^a   Einen, Mali ^a   Mignot, Emmanuel ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; HLA DQB1 ANTIGEN; OREXIN; PREDNISONE; BENZHYDRYL DERIVATIVE; CARRIER PROTEIN; CENTRAL STIMULANT AGENT; CYCLOHEXANOL DERIVATIVE; HLA ANTIGEN; IMMUNOSUPPRESSIVE AGENT; MODAFINIL; NEUROPEPTIDE; OREXINS; SEROTONIN UPTAKE INHIBITOR; SIGNAL PEPTIDE; VENLAFAXINE;

ARTICLE; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CYTOLOGY; HLA TYPING; HUMAN; HYPOTHALAMUS; IMMUNOSUPPRESSIVE TREATMENT; MALE; NARCOLEPSY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; SCHOOL CHILD; ACUTE DISEASE; CEREBROSPINAL FLUID; CHILD; IMMUNOLOGY; METABOLISM; POLYSOMNOGRAPHY;

ACUTE DISEASE; BENZHYDRYL COMPOUNDS; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; CYCLOHEXANOLS; HLA ANTIGENS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NARCOLEPSY; NEUROPEPTIDES; POLYSOMNOGRAPHY; PREDNISONE; SEROTONIN UPTAKE INHIBITORS;

EID: 0347120596     PISSN: 01618105     EISSN: None     Source Type: Journal    
DOI: 10.1093/sleep/26.7.809     Document Type: Article

References (7)

1. Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E. Hypocretin (orexin) deficiency in human narcolepsy Lancet 2000;355:39-40.
2. Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59:1553-62.
3. Tsukamoto H, Ishikawa T, Fujii Y, Fukumizu M, Sugai K, Kanbayashi T Undetectable levels of CSF hypocretin-1 (orexin-A) in two prepubertal boys with narcolepsy. Neuropediatrics 2002;33:51-2.
4. Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000;6:991-7.
5. Thannickal TC, Moore RY, Nienhuis R, et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron. 2000;27:469-74.
6. Mignot E, Lin L, Rogers W, Honda Y, et al. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataptexy in three ethnic groups. Am J Hum Genet 200;68:686-99.
7. Matsuki K, Juji T, Honda Y. Immunological features of narcolepsy in Japan. In: Honda Y, Juji T, eds. HLA in Narcolepsy. Berlin Springer-Verlag; 1988:150-7