Equine motor neuron disease is not linked to Cu/Zn superoxide dismutase mutations: Sequence analysis of the equine Cu/Zn superoxide dismutase cDNA

Gene

Volumn 178, Issue 1-2, 1996, Pages 83-88

  De La Rúa Domènech, Ricardo ^a   Wiedmann, Martin ^b   Mohammed, Hussni O ^a   Cummings, John F ^a   Divers, Thomas J ^a   Batt, Carl A ^b  

^a Animal Health Diagnostic Center   (United States)

^b Plant Breeding and Genetics Section in the School of Integrative Plant Science   (United States)

Author keywords

Amyotrophic lateral sclerosis; EMND SOD1 linkage; Horse; RT PCR cloning

Indexed keywords

COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; ENZYME ACTIVE SITE; EXON; GENE MUTATION; GENE SEQUENCE; HORSE; HUMAN; HUMAN CELL; LEUKOCYTE; MOLECULAR CLONING; MOTOR NEURON DISEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SILENT GENE;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 0347019746     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(96)00339-3     Document Type: Article

References (21)

1. Bannister, W.H., Bannister, J.V., Barra, D., Bond, J. and Bossa, F. (1991) Evolutionary aspects of superoxide dismutase: the copper/ zinc enzyme. Free Rad. Res. Commun. 12/13, 349-361.
2. Cummings, J.F., George, C., de Lahunta, A., Fuhrer, L., Valentine, B.A., Cooper, B.J., Summers, B.A., Huxtable, C.K. and Mohammed, H.O. (1990) Equine motor neuron disease: a preliminary report. Cornell Vet. 80, 357-379.
3. Deng, H-X., Hentati, A., Tainer, J.A., Iqbal, Z., Cayabyab, A., Hung, W-Y., Getzoff, E.D., Hu, P., Herzfeldt, B., Roos, R.P., Warner, C., Deng, G., Soriano, E., Smyth, C., Parge, H.E., Amed, A., Roses, A.D., Hallewell, R.A., Pericak-Vance, M.A. and Siddique, T. (1993) Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science 261, 1047-1051.
4. Divers, T.J., Mohammed, H.O., Cummings, J.F., Valentine, B.A., de Lahunta, A., Jackson, C.A. and Summers, B.A. (1994) Equine motor neuron disease: findings in twenty-eight horses. Equine Vet. J. 26, 409-415.
5. Fridovich, I. (1986) Superoxide dismutases. Adv. Enzymol. 58, 61-97.
6. Gurney, M.E., Pu, H., Chiu A.Y., Dal Canto, M.C., Polchow, C.Y., Alexander, D.D., Caliendo, J., Hentati, A., Kwon, Y.W., Deng, H., Chen, W., Zhai, P., Sufit, R.L. and Siddique, T. (1994) Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264, 1772-1775.
7. Halliwell, B. (1992) Oxygen radicals as key mediators in neurological disease: fact or fiction? Ann. Neurol. 32, S10-S15.
8. Hirano, M., Fujii, J., Nagai, Y., Sonobe, M., Okamoto, K., Araki, H., Taniguchi, N. and Ueno, S. (1994) A new variant Cu/Zn superoxide dismutase (Val7→Glu) deduced from lymphocyte mRNA sequences from Japanese patients with familial amyotrophic lateral sclerosis. Bioch. Biophys. Res. Commun. 204, 572-577.
9. Lerch, K. and Ammer, D. (1981) Ammo acid sequence of Cu/Zn superoxide dismutase from horse liver. J. Biol. Chem. 256, 11545-11551.
10. Levanon. D., Lieman-Hurwitz, J., Dafni, N., Widgerson, M., Sherman, L., Bernstein, Y., Laver-Rudich, Z., Danciger, E., Stein, O. and Groner, Y. (1985) Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase. EMBO J. 4, 77-84.
11. Mohammed, H.O., Cummings, J.F., Divers, T.J., de Lahunta, A., George, C., Fuhrer, L., Valentine, B.A., Summers, B.A., Farrow, B.R.H., Trembicki, K. and Mauskopf, A. (1993) Risk factors associated with equine motor neuron disease. Neurology 43, 966-977.
12. Mulder, D.W., Kurland, L.T., Offord, K.P. and Beard, M. (1986) Familial adult motor neuron disease: amyotrophic lateral sclerosis. Neurology 36, 511-517.
13. Oppenheimer, D.R. (1984) Diseases of the motor neurons and pyramidal tracts. In: Adams, J.H., Corsellis, J.A.N. and Duchen, L.W. (Eds.), Greenfield's Neuropathology, 4th edn. John Wiley and Sons, New York, NY, pp. 726-734.
14. Parker, L.T., Deng, Q., Zakeri, C., Carlson, C., Nickerson, D.A. and Kwok, P.Y. (1995) Peak height variations in automated sequencing of PCR products using Taq dye terminator chemistry. BioTechniques 19, 116-121.
15. Pramatarova, A., Goto, J., Nanba, E., Nakashima, K., Takahashi, K., Takagi, A., Kanazawa, I., Figlewicz, D.A. and Rouleau, G.A. (1994) A two basepair deletion in the SOD1 gene causes familial amyotrophic lateral sclerosis. Hum. Mol. Genet. 11, 2061-2062.
16. Pramatarova, A., Figlewicz, D.A., Krizus, A., Han, F-Y., Ceballos-Picot, I., Nicole, A., Dib, M., Meininger, V., Brown, R.H. and Rouleau, G.A. (1995) Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis. Am. J. Hum. Genet. 56, 592-596.
17. Robberecht, W., Sapp, P., Viaene, M.K., Rosen, D., McKenna-Yasek, D., Haines, J., Horvitz, R., Theys, P. and Brown Jr., R. (1994) Cu/ Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 62, 384-387.
18. Rosen, D.R., Siddique, T., Patterson, D., Figlewicz, D.A., Sapp. P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J., Deng, H-X., Rahmani, Z., Krizus, A., McKenna-Yasek, D., Cayabyab, A., Gaston, S.M., Berger, R., Tanzi, R.E., Halperin, J., Herzfeldt, B., Van den Bergh, R., Hung, W.-Y., Bird, T., Deng, G., Mulder, D.W., Smyth, C., Laing, N.G., Soriano, E., Pericak-Vance, M.A., Haines, J., Rouleau, G.A., Gusella, J.S., Horvitz, H.R. and Brown, R.H. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
19. Siddique, T., Figlewicz, D.A., Pericak-Vance, M.A., Haines, J.L., Rouleau, G., Jeffers, A.J., Sapp, P., Hung, W.-Y., Bebout, J., McKenna-Yasek, D., Deng, G., Horvitz, H.R., Gusella, J.S., Brown, R.H. and Roses, A.D. (1991) Linkage of a gene causing familial ALS to chromosome 21 and evidence of genetic-locus heterogeneity. N. Engl. J. Med. 324, 1381-1384.
20. Sillevis-Smitt, P.A.E. and De Jong, J.M.B.V. (1988) Animal models of amyotrophic lateral sclerosis and the spinal muscular atrophies. J. Neurol. Sci. 91, 231-258.
21. Wiedau-Pazos, M., Goto, J.J., Rabizadeh, S., Gralla E.B., Roe, J.A., Lee, M.K., Valentine, J.S. and Bredesen, D.E. (1996) Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science 271, 515-518.