Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: A model for the bi-product complex following cleavage of a peptide substrate

Biochemical and Biophysical Research Communications

Volumn 314, Issue 2, 2004, Pages 638-645

  Wlodawer, Alexander ^a   Li, Mi ^a,b   Gustchina, Alla ^a   Oyama, Hiroshi ^c   Oda, Kohei ^c   Beyer, Bret B ^d   Clemente, Jose ^d   Dunn, Ben M ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

Inhibitor binding; Reaction products; Serine carboxyl proteinases; Substrate specificity

Indexed keywords

AMINO ACID; BACTERIAL ENZYME; PEPTIDE LIBRARY; SEDOLISIN; SERINE CARBOXYPEPTIDASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; ENZYME SPECIFICITY; FLUORESCENCE; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS;

BACTERIA (MICROORGANISMS); FELIS CATUS; PSEUDOMONAS;

EID: 0347004614     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.12.130     Document Type: Article

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