Estimation of the number of neurons in the hippocampus of rats with penicillin induced epilepsy

Image Analysis and Stereology

Volumn 21, Issue 2, 2002, Pages 117-120

  Akdogan, Ilgaz ^a   Unal, Nedim ^b   Adiguzel, Esat ^a  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b OSMANGAZI UNIVERSITY MEDICAL FACULTY   (Turkey)

Author keywords

Experimental epilepsy; Hippocampus; Optical fractionator; Rat; Total neuron number

Indexed keywords

EID: 0346992901     PISSN: 15803139     EISSN: 18545165     Source Type: Journal    
DOI: 10.5566/ias.v21.p117-120     Document Type: Article

References (16)

1. Biziere K, Chambón JP (1987). Modeles Animaux D'epilepsie et Crises Experimentales. Rev Neurol (Paris) 143(5):329-40.
2. Boss BD, Turlejski K, Stanfield BB, Cowan WM (1987). On the numbers of neurons in fields CA1 and CA3 of the hippocampus of Sprague-Dawley and Wistar rats. Brain Research 406:280-7.
3. Coggeshall RE, Lekan HA (1996). Methods for determining numbers of cells and synapses: A case for more uniform standards of review. The Journal of Comparative Neurology 364:6-15.
4. Dam AM (1982). Hippocampal neuron loss in epilepsy and after experimental seizures. Acta Neurol Scandinav 66:601-42.
5. Fisher RS (1989). Animal Models of the Epilepsies. Brain Research Rev 14:245-78.
6. Fletcher AJ (1987). In: Berkow R, Ed. The Merck Manual of Diagnosis and Therapy. Fifteenth Edition. Merck Sharp and Dohme Research Laboratories, pp. 1366.
7. Gundersen HJG (1986). Stereology of arbitrary particles, A review of unbiased number size estimators and the presentation of some new ones, in memory of William R. Thompson. Journal of Microscopy 143:3-45.
8. Gundersen HJG, Bagger P, Bendtsen TF, Evans SM, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, West MJ (1988). The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis, review article. APMIS 96:857-81.
9. Howard CV, Reed MG (1998). Unbiased Stereology Three-Dimensional Measurement in Microscopy. BIOS Scientific Publishers, 94-5.
10. Korkmaz A, Tunkaya L (1997). Estimation of the section thickness and optical disector height with a simple calibration method. Journal of Microscopy 187(2): 104-9.
11. Lindsay KW, Bone I, Callender R (1997). Neurology and Neurosurgery Illustrated. 3th edition. Churchill Livingstone, pp.88.
12. Oorschot DE (1994). Are you using neuronal densities, synaptic densities or neurochemical densities as your definitive data? There is a better way to go. Progress in Neurobiology 44:223-47.
13. Sagratella S, Niglio T, Carolis AS (1985). An investigation on the mechanism of anticonvulsant action of ketamine and phencyclidine on convulsions due to cortical application of penicillin in rabbits. Pharmacological Research Comm 17(8):773-86.
14. West MJ, Slomianka L, Gundersen HJG (1991). Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. The Anatomical Record 231:482-7.
15. West MJ (1993). New stereological methods for counting neurons. Neurobiology of Aging 14:275-85.
16. West MJ, Ostergaard K, Andreassen OA, Finsen B (1996). Estimation of the number of somatostatin neurons in the striatum: An in situ hybridization study using the optical fractionator method. The Journal of Comparative Neurology 370:11-22.