Effect of flaxseed and wheat bran on serum hormones and lignan excretion in premenopausal women

Journal of the American College of Nutrition

Volumn 22, Issue 6, 2003, Pages 550-554

  Frische, Elsa J ^a   Hutchins, Andrea M ^a   Martini, Margaret C ^a   Thomas, William ^b   Slavin, Joanne L ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Flaxseed; Hormones; Human; Lignans; Wheat bran

Indexed keywords

LIGNAN; SEX HORMONE BINDING GLOBULIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; FEMALE; FOOD INTAKE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; LINSEED; LUTEAL PHASE; MENSTRUAL CYCLE; NORMAL HUMAN; PREMENOPAUSE; RANDOMIZED CONTROLLED TRIAL; URINALYSIS; URINARY EXCRETION; WHEAT BRAN;

ADULT; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; DIETARY FIBER; DRUG THERAPY, COMBINATION; ESTROGENS; FEMALE; FLAX; HUMANS; LIGNANS; PHYTOTHERAPY; PREMENOPAUSE; SEX HORMONE-BINDING GLOBULIN; TREATMENT OUTCOME;

TRITICUM AESTIVUM;

EID: 0346887177     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2003.10719335     Document Type: Article

References (19)

1. Adlercreutz H, Mazur W: Phyto-oestrogens and western diseases. Ann Med 29:95-120, 1997.
2. Nesbitt PD, Lam Y, Thompson LU: Human metabolism of mammalian lignan precursors in raw and processed flaxseed. Am J Clin Nutr 69:549-555, 1999.
3. Axelson M., Sjovall J, Gustafsson BE, Setchell KDR: Origin of lignans in mammals and identification of a precursor from plants. Nature 298:659-660, 1982.
4. Lampe JW: Isoflavonoid and lignan phytoestrogens as dietary biomarkers. J Nutr 133:956S-964S, 2003.
5. Goldin BR, Adlercreutz H, Gorbach SL, Warram JH, Dwyer JT, Swenson L, Woods MN: Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. N Engl J Med 307: 1542-1547, 1982.
6. Bagga D, Ashley JM, Geffrey SP, Wang H-J, Barnard RJ, Koren-man S, Heber D: Effects of a very low fat, high fiber diet on serum hormones and menstrual function. Cancer 76:2491-2496, 1995.
7. Adlercreutz H, Fotsis T, Bannwart C, Hämäläinen E, Bloigu S, Ollus A: Urinary estrogen profile determination in young Finnish vegetarian and omnivorous women. J Steroid Biochem 24:289-296, 1986.
8. Rose DP, Lubin M, Connolly JM: Effects of diet supplementation with wheat bran on serum estrogen levels in the follicular and luteal phases of the menstrual cycle. Nutrition 13:535-539, 1997.
9. Tew BY, Xu X, Wang HJ, Murphy PA, Hendrich S: A diet high in wheat fiber decreases the bioavailability of soybean isoflavones in a single meal fed to women. J Nutr 126:871-877, 1996.
10. Haggans CJ, Travelli EJ, Thomas W, Martini MC, Slavin JL: The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women. Cancer Epidemiol Biomarkers Prev 9:719-725, 2000.
11. Adlercreutz H, Fotsis T, Bannwart C, Wahala K, Brunow G, Hase T: Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clin Chem Acta 199:263-278, 1991.
12. Adlercreutz H, Fotsis T, Hockerstedt K, Hamalainen E, Bannwart C, Bloigu S, Valtonen A, Ollus A: Diet and urinary estrogen profile in premenopausal omnivorous and vegetarian women and in premenopausal women with breast cancer. J Steroid Biochem 34:527-530, 1989.
13. Hutchins AM, Martini MC, Olson BA, Thomas W, Slavin JL: Flaxseed consumption influences endogenous hormone and binding protein concentrations in postmenopausal women. Nutr Cancer 39:58-65, 2001.
14. Shultz TD, Bonorden WR, Seaman WR: Effect of short-term flaxseed consumption on lignan and sex hormone metabolism in men. Nutr Res 11:1089-1100, 1991.
15. Lampe JW, Martini MC, Kurzer MS, Adlercreutz H Slavin JL: Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. Am J Clin Nutr 60:122-128, 1994.
16. Kurzer MS, Lampe JW, Martini MC, Adlercreutz H: Fecal lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. Cancer Epidemiol Biomarkers Prev 4:353-358, 1995.
17. Phipps WR, Martini MC, Lampe JW, Slavin JL, Kurzer MS: Effect of flax seed ingestion on the menstrual cycle. J Clin Endocrinol Metab 77:1215-1219, 1993.
18. Whitten C, Shultz TD: Binding of steroid hormones in vitro by water insoluble dietary fiber. Nutr Res 8:1223-1235, 1988.
19. Lampe JW, Skor HE, Wahala K, Howald WN, Chen C: Wheat bran and soy protein feeding do not alter urinary excretion of the isflavon equol in premenopausal women. J Nutr 131:740-744, 2001.