First asymmetric syntheses of 6-substituted nipecotic acid derivatives

Tetrahedron

Volumn 60, Issue 2, 2004, Pages 307-318

  Hoesl, Cornelia E ^a   Hofner G ^a   Wanner, Klaus T ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Asymmetric synthesis; GABA uptake; Nipecotic acid

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; AMINO ACID TRANSPORTER; METHYL [4 (DIMETHYLPHENYLSILYL) 6 (2 [1,3]DIOXOLAN 2 YLETHYL) 1 (5,8,8 TRIMETHYL 2 OXO 3 OXABICYCLO[3.2.1]OCTYLCARBONYL)] 1,6 DIHYDROPYRIDINE 3 CARBOXYLATE; METHYL[4 (DIMETHYLPHENYLSILYL) 6 (2 [1,3]DIOXOLAN 2 YLETHYL) 1 (5,8,8 TRIMETHYL 2 OXO 3 OXABICYCLO[3.2.1]OCTYLCARBONYL)] 1,6 DIHYDROPYRIDINE 3 CARBOXYLATE; NIPECOTIC ACID DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDINIUM DERIVATIVE; SILANE DERIVATIVE; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ALKYLATION; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORNER REACTION; INFRARED SPECTROSCOPY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY;

EID: 0346887158     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.11.014     Document Type: Article

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