EGFR: Assessment of EGFR status and tumoral expression;Récepteur du facteur de croissance épidermique: Méthodes d'évaluation du statut et expression tumorale

Bulletin du Cancer

Volumn 90, Issue SPEC. ISS., 2003, Pages

  Penault Llorca, Frédérique ^a  

^a CENTRE JEAN PERRIN   (France)

Author keywords

Epidermal growth factor; Immunohistochemistry; In situ hybridization; Targeted therapy; Tumors

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA UROGASTRONE; LIGAND; TYROSINE KINASE RECEPTOR;

DRUG TARGETING; EPITHELIUM TUMOR; FLUORESCENCE HISTOCHEMISTRY; GENE AMPLIFICATION; GENE MUTATION; GENETIC TRANSCRIPTION; HEAD AND NECK CANCER; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG DYSPLASIA; MOUTH MUCOSA; ONCOGENE NEU; PROTEIN EXPRESSION; PROTEIN TARGETING; REVIEW;

HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; NEOPLASM PROTEINS; NEOPLASMS; ORGAN SPECIFICITY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2;

EID: 0346874161     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (37)

1. L'Allemain G. La famille des récepteurs HER-ErbB et ses ligands: mécanismes d'activation, signalisation et dérégulations dans le cancer. Bull Cancer 2003; 90 (spécial): S179-85
2. Leylands-Jones B. Trastuzumab: hopes and realities. Lancet Oncol 2002; 3: 137-44.
3. Slimane K, Fayette J, Masmoudi A, Perez A, Armand JP. Panorama des inhibiteurs du récepteur à l'EGF (à l'exclusion du ZD1839 et du C225). Bull Cancer 2003; 90 (spécial): S214-9.
4. Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000; 19: 6550-65.
5. Arteaga CL. Epidermal growth factor receptor dependence in human tumor: more than just expression. Oncologist 2002; 7 (suppl. 4): 31-9.
6. Penault-Llorca F, Balaton AJ, Sabourin JC, Le Doussal V et le Groupe d'évaluation des facteurs pronostiques par immunohistochimie dans les cancers du sein (Gefpics). Évaluation immunohistochimique du statut HER2 dans les carcinomes mammaires infiltrants: mise au point du protocole technique et de la lecture des résultats - Recommandations. Ann Pathol 2002; 22: 150-7.
7. Van de Vijver M. Assessment of the need and appropriate method for testing for the human epidermal growth factor receptor-2 (HER2). Eur J Cancer 2001; 37: S11-7.
8. Bilous M, Dowsett M, Hanna W, Isola J, Lebeau A, Moreno A, et al. Current perspectives on HER2 testing: a review of national testing guidelines. Mod Pathol 2003; 16: 173-82.
9. Herbst RS, Langer CJ. Epidermal growth factor receptors as a target for cancer treatment: the emerging role of IMC-C225 in the treatment of lung and head and neck cancers. Semin Oncol 2002; 29: 27-36.
10. Yarden Y. The EGFR family and its ligands in human cancer: signalling mechanism and therapeutic opportunities. Eur J Cancer 2001; 37: S3-8.
11. Woodburn JR. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacother 1999; 82: 241-50.
12. Moscatello DK, Holgado-Madruga M, Emlet DR, Montgomery RB, Wong AJ. Constitutive activation of phosphatidylinositol 3-kinase by a naturally occuring mutant epidermal growth factor receptor. J Biol Chem 1998; 273: 200-6.
13. Salomon DS, Brandt R, Ciardello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995; 19: 183-232.
14. Albanell J, Rojo F, Averbuch S Feyereislova A, Mascaro JM, Herbst R, et al. Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition. J Clin Oncol 2002; 20: 110-24.
15. Goike HM, Asplund AC, Pettersson EH, Liu L, Sanoudou D, Collins VP. Acquired rearrangement of an amplified epidermal growth factor receptor (EGFR) gene in a human glioblastoma xenograft. J Neuropathol Exp Neurol 1999; 58: 697-701.
16. Amare PS, Varghese C, Bharde S, Narasimhamoorthy NK, Desai S, Advani SH, et al. Cancer Genet Cytogen 2001; 125: 139-46.
17. Nicholson RI, Gee JM, Harper ME. EGFR and cancer prognosis. Eur J Cancer 2001; 37: S9-15.
18. Goldstein NS, Armin M. Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system. Cancer 2001; 92: 1331-46.
19. Johns TG, Stockert E, Ritter G, Jungbluth AA, Huang HJ, Cavenee WK, et al. Novel monoclonal antibody specific for the epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene. Int J Cancer 2002; 98: 398-408.
20. Frederick L, Wang XY, Eley G, James CD. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res 2000; 60: 1383-7.
21. Rodrigo JP, Gonzalez MV, Lazo PS, Ramos S, Coto E, Alvarez I, et al. Genetic alterations in squamous cell carcinomas of the hypopharynx with correlations to clinicopathological features. Oral Oncol 2002; 38: 357-63.
22. Hoffmann TK, Ballo H, Braunstein S, Van Lierop A, Wagenmann M, Bier H. Serum level and tissue expression of c-erbB-1 and c-erbB-2 proto-oncogene products in patients with squamous cell carcinoma of the head and neck. Oral Oncol 2001; 37: 50-6.
23. Jost M, Kari C, Rodeck U. The EGF receptor: an essential regulator of multiple epidermal functions. Eur J Dermatol 2000; 10: 505-10.
24. Busam KJ, Capodieci P, Motzer R, Kiehn T, Phelan D, Halpern AC. Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 2001; 144: 1169-76.
25. Putti TC, To KF, Hsu HC, Chan AT, Lai GM, Tse G, et al. Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: a multicentre immunohistochemical study in the Asia-Pacific region. Histopathology 2002; 41: 144-51.
26. Franklin WA, Veve R, Hirsh FR, et al. Epidermal growth factor receptor family in lung cancer and premalignancy. Semin Oncol 2002; 29: 3-14.
27. Lee JC, Wang ST, Chow NH, Yang HB. Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery. Eur J Cancer 2002; 38: 1065-71.
28. Mathur SP, Mathur RS, Rust PF, Young RC. Human papilloma virus (HPV)-E6/E7 and epidermal growth factor receptor (EGF-R) protein levels in cervical cancer and cervical intraepithelial neoplasia (CIN). Am J Reprod Immunol 2001; 46: 280-7.
29. Neskovic-Konstantinovic Z, Nikolic-Vukosavljevic D, Brankovic-Magic M, Kanjer K, Gavrilovic D, Mitrovic L, Borojevic N, et al. Expression of epidermal growth factor receptor in breast cancer, from early stages to advanced disease. J Exp Clin Cancer Res 1999; 18: 347-55.
30. Ge H, Gong X, Tang CK. Evidence of high incidence of EGFRvIII expression and coexpression with EGFR in human invasive breast cancer by laser capture microdissection and immunohistochemical analysis. Int J Cancer 2002; 98: 357-61.
31. Harlozinska A, Bar JK, Sobanska E, Goluda M. Epidermal growth factor receptor and c-erbB-2 oncoproteins in tissue and tumor effusion cells of histopathologically different ovarian neoplasms. Tumour Biol 1998; 19: 364-73.
32. Tewari KS, Kyshtoobayeva AS, Mehta RS, Yu IR, Burger RA, DiSaia PJ, et al. Biomarker conservation in primary and metastatic epithelial ovarian cancer. Gynecol Oncol 2000; 78: 130-6.
33. Moch H, Sauter G, Gasser TC, Bubendorf L, Richter J, Presti JC, et al. EGF-R gene copy number changes in renal cell carcinoma detected by fluorescence in situ hybridization. J Pathol 1998; 184: 424-9.
34. De Miguel P, Royuela, Bethencourt R, Ruiz A, Fraile B, Paniagua R. Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostates. Cytokine 1999; 11: 722-7.
35. Cardillo MR, Castagna G, Memeo L, De Bernardinis E, Di Silverio F. Epidermal growth factor receptor, MUC-1 and MUC-2 in bladder cancer. J Exp Clin Cancer Res 2000; 19: 225-33.
36. Lonardo F, Dragnev KH, Freemantle SJ, Ma Y, Memoli N, Sekula D, et al. Evidence for the epidermal growth factor receptor as a target for lung cancer prevention. Clin Cancer Res 2002; 8: 54-60.
37. Bei R, Pompa G, Vitolo D, Moriconi E, Ciocci L, Quaranta M, et al. Co-localization of multiple ErbB receptors in stratified epithelium of oral squamous cell carcinoma. J Pathol 2001; 195: 343-8.