Expression of epidermal growth factor receptor in breast cancer, from early stages to advanced disease

Journal of Experimental and Clinical Cancer Research

Volumn 18, Issue 3, 1999, Pages 347-355

  Neskovic Konstantinovic Z ^a,d   Nikolic Vukosavljevic D ^b   Brankovic Magic M ^b   Kanjer, K ^b   Gavrilovic D ^c   Mitrovic L ^a   Borojevic N ^a   Vukotic Dj ^d   Spuzic I ^e  

^a Dept Medical Oncology ^*  (Serbia)

^b Lab Receptors Biol Malignant Cells   (Serbia)

^c Data Center   (Serbia)

^d INSTITUTE FOR ONCOLOGY AND RADIOLOGY OF SERBIA   (Serbia)

^e SERBIAN ACADEMY OF SCIENCES AND ARTS   (Serbia)

Author keywords

Breast cancer; EGF R; Predictive factors; Prognosis; Steroid receptors

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; STEROID RECEPTOR;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER STAGING; CANCER SURVIVAL; DISEASE COURSE; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

EID: 2442722155     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Klijn J.G.M., Berns P.M.J.J., Schmitz P.I.M., Foekens J.A.: The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients. Endocrine Rev. 13: 3-17, 1992.
2. Harris A.L., Nicholson S., Sainsbury J.R.C., Farndon J., Wright C.: Epidermal growth factor receptors in breast cancer: association with early relapse and death, poor response to hormones and interactions with neu. J. Steroid. Biochem. 34: 123-131, 1989.
3. Nicholson S., Wright C., Sainsbury J.R.C. et al.: Epidermal growth factor receptor (EGFr) as a marker for poor prognosis in node-negative breast cancer patients: Neu and tamoxifen failure. J. Steroid. Biochem. Mol. Biol. 37: 811-815, 1990.
4. Hawkins R.A., Killen E., Whittle I.R., Jack W.J.L., Chetty U., Prescott R.J.: Epidermal growth factor receptors in intracranial and breast tumours: their clinical significance. Br. J. Cancer 63: 553-560, 1991.
5. Fox S.B., Smith K., Hollyer J., Greenall M., Hastrich D., Harris A.L.: The epidermal growth factor receptor as a prognostic marker: Results of 370 patients and review of 3009 patients. Breast Cancer Res. Treat. 29: 41-49, 1994.
6. Capelletti V., Brivio M., Miodini P., Granata G., Coradini D., Di Fronzo G.: Simultaneous estimation of epidermal growth factor receptor and steroid receptors in a series of 136 resectable primary breast tumors. Tumor Biol. 9: 200-211, 1988.
7. Delarue J.C., Friedman S., Mouriesse H. et al.: Epidermal growth factor receptor in human breast cancers: correlation with estrogen and progesterone receptors. Breast Cancer Res. Treat. 11: 173-178, 1988.
8. Dittadi R., Donisi P.M., Brazzale A., Cappellozza L., Bruscagnin G., Gion M.: Epidermal growth factor receptor in breast cancer. Comparison with non malignant breast tissue. Br. J. Cancer 67: 7-9, 1993.
9. Railo M., Smitten K.V., Pekonen F.: The prognostic value of epidermal growth factor receptor (EGFR) in breast cancer patients. Results of a follow-up study on 149 patients. Acta Oncologica 33: 13-17, 1994.
10. Fitzpatrick S.L., LaChance M.P., Shultz G.S.: Characterization of epidermal growth factor receptor and action on human breast cancer cells in culture. Cancer Res. 44:3442-3447, 1984.
11. Bevilacqua P., Gasparini G., Dal Fior S., Corradi G.: Immunocytochemical determination of epidermal growth factor receptor with monoclonal EGFR1 antibody in primary breast cancer patients. Oncology 47: 313-317, 1990.
12. Gasparini G., Boracchi P., Bevilacqua P., Mezzetti M., Pozza F., Weidner N.: A multiparametric study on the prognostic value of epidermal growth factor receptor in operable breast carcinoma. Breast Caner Res. Treat. 29: 59-71, 1994.
13. Mon T., Morimoto T., Komaki K., Monden Y.: Comparison of estrogen receptor and epidermal growth factor receptor content of primary and involved nodes in human breast cancer. Cancer 68: 532-537, 1991.
14. Gohring U.-J., Ahr A., Scharl A. et al.: Immunocytochemical detection of epidermal growth factor receptor lacks prognostic significance for breast carcinoma. J. Soc. Gynecol. Invest. 2: 653-659, 1995.
15. Pirinen R., Lipponen P., Syrjanen K.: Expression of epidermal growth factor receptor(EGFR) in breast cancer as related to clinical, prognostic and cytometric factors. Anticancer Res. 15: 2835-2840, 1995.
16. Pekonen F., Partanen S., Makinen T., Rutanen E.-M.: Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer. Cancer Res. 48: 1343-1347, 1988.
17. Sainsbury J.R.C., Needham G.K., Farndon J.R., Malcolm A.J., Harris A.L.: Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer. Lancet 1: 1398-1402, 1987.
18. Lewis S., Locker A., Todd J.H., Bell J.A., Nicholson R., Elston C.W., Blarney R.W., Ellis I.O.: Expression of epidermal growth factor receptor in breast carcinoma. J. Clin. Pathol. 43: 385-389, 1990.
19. Elledge R.M., McGuire W.L., Osborne C.K.: Prognostic factors in breast cancer. Semin. Oncol. 19: 244-253, 1992.
20. Hawkins R.A., White G., Bundred J., Dixon J.M.J. et al.: Prognostic significance of oestrogen and progesterone receptor activities in breast cancer. Br. J. Surg. 74: 1009-1013, 1987.
21. Nicholson S., Halcrow P., Sainsbury J.R.C., Angus B., Chambers P., Farndon J.R., Harris A.L.: Epidermal growth factor receptor (EGFr) status associated with failure of primary endocrine therapy in elderly postmenopausal patients with breast cancer. Br. J. Cancer 58: 810-814, 1988.
22. Nicholson S., Sainsbury C., Halcrow P., Chambers P., Farndon J.R., Harris A.L.: Expression of epidermal growth factor receptors associated with lack of response to endocrine therapy in recurrent breast cancer. Lancet 1: 182-184, 1989.
23. Wright C., Nicholson S., Angus B., Sainsbury J.R.C., Farndon J., Cairns J., Harris A.L., Horne C.H.W.: Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer. Br. J. Cancer 65: 118-121, 1992.
24. Nicholson R.I., McClelland R.A., Finlay P., Eaton C.L., Gullick W.J., Dixon A.R., Robertson J.F.R., Ellis I.O., Blarney R.W.: Relationship between EGF-R, c-erbB-2 protein expression and Ki67 immunostaining in breast cancer and hormone sensitivity. Eur. J. Cancer 29A: 1018-1023, 1993.
25. Guerin M., Gabillot M., Mathieu M.-C. et al.: Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int. J. Cancer 43: 201-208, 1989.
26. Klijn J.G.M., Berns E.M.J.J., Bontenbal M., Foekens J.: Cell biological factors associated with the response of breast cancer to systemic treatment. Cancer Treat. Rev. 19, Suppl B: 45-63, 1993.
27. Muss H.B., Thor A.D., Berry D.A. et al.: C-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N. Engl. J. Med. 330: 1260-1266, 1994.
28. Fisher E.R., Redmond C., Fisher B.: Pathologic findings from the National Surgical Adjuvant Breast Project. VIII. Relationship of chemotherapeutic responsiveness to tumor differentiation. Cancer 51: 181-191, 1983.
29. Hanauske A.-R., Osborne C.K., Chamness G.C. et al.: Alteration of EGF-receptor binding in human breast cancer cells by antineoplastic agents. Eur J. Cancer Clin. Oncol. 23: 545-551, 1987.
30. EORTC Breast Cancer Cooperative Group. Revision of the standards for the assessment of hormone receptors on human breast cancer. Eur. J. Cancer 16: 1513-1515, 1980.
31. Wittlif J.L., Pasio R., Bland K.I.: Steroid and peptide hormone receptor identified in breast tissue. In: Bland K.I., Copeland III E.M., eds. The breast - Comprehensive management of benign and malignant disease. Philadelphia: WB Sounders Comp, 1991: 900-936.
32. Hayward J.L., Rubens R.D., Carbone P.P., Henson J.C., Kumaoka S., Segaloff A.: Assessment of response to therapy in advanced breast cancer. Br. J. Cancer 35: 292-298, 1977.
33. Nešković-Konstantinović Z., Nikolić -Vukosavljević D., Branković-Magiĺ M., Kanjer K., Spužić I.: The content of epidermal growth factor receptor in breast cancer: Association with classical parameters of prognosis and steroid receptor status. J. BUON 1: 53-57, 1996.
34. Nešković-Konstantinović Z., Nikolić -Vukosavljević D., Branković-Magiĺ M., Kanjer K., Spužić I.: Predictive role of EGF-R in locally advanced and metastatic breast cancer. Ann. Oncol. 7, Suppl 5: Abstract No. 128P, 1996.
35. Thorpe S.M., Rose C.: Oestrogen and progesterone receptors determinations in breast cancer: technology and biology. Cancer Survays 5: 506-525, 1986.
36. McGuire W.L., Chamness G.C., Fuqua S.A.W.: Estrogen receptor variants in clinical breast cancer. Mol. Endocrinol. 5: 1571-1577, 1991.
37. Klijn J.G.M., Look M.P., Portenhen H. et al.: The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: results of a 10 year follow-up study. Breast Cancer Res. Treat. 29: 73-83, 1994.
38. Branković-Magiĺ M., Nikolić-Vukosavljević D., Nešković-Konstantinović Z., Kanjer K., Spužić I.: Variations in the content of steroid receptors in breast cancer. Comparison between primary tumors and metastatic lesions. Acta Oncol. 31: 629-633, 1992.
39. Branković-Magiĺ M., Nikolić-Vukosavljević D., Nešković-Konstantinović Z., Kanjer K., Spužić I.: Steroid receptors in pleural effusions of advanced breast cancer patients. Int. J. Biol. Markers 10: 143-148, 1995.
40. Crysogelos S.A., Dickson R.B.: EGF receptor expression, regulation, and function in breast cancer. Breast Cancer Res. Treat. 29: 29-40, 1994.
41. Dotzlaw H., Miller T., Karvelas J., Murphy L.C.: Epidermal growth factor gene expression in human breast cancer biopsy samples: Relationship to estrogen and progesterone receptor gene expression. Cancer Res. 50: 4204-4208, 1990.
42. Sharma A.K., Horgan K., Douglas-Jones A.G., McCleland R.A., Nicholson R.I.: Double immunocytochemical assay of receptors for oestrogen (ER) and epidermal growth factor (EGFR). Breast Cancer Res. Treat. 23: 185-188, 1992.