Spontaneous Regression of Severe Acquired Infantile Hypothyroidism Associated with Multiple Liver Hemangiomas

Pediatrics

Volumn 112, Issue 6 I, 2003, Pages 1424-1426

  Konrad, Daniel ^a   Ellis, Graham ^a,b   Perlman, Kusiel ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b ST JOHN'S HOSPITAL   (United Kingdom)

Author keywords

Free T4; L thyroxine; Reverse T3; Type 3 iodothyronine deiodinase

Indexed keywords

LEVOTHYROXINE; LIOTHYRONINE; THYROTROPIN; THYROXINE;

ARTICLE; CASE REPORT; DISEASE ASSOCIATION; HORMONE SUBSTITUTION; HUMAN; HYPOTHYROIDISM; INFANT; LIVER HEMANGIOMA; LIVER TUMOR; MALE; PRIORITY JOURNAL; THYROID DISEASE; THYROID FUNCTION TEST; TREATMENT OUTCOME;

HEMANGIOMA; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOTHYROIDISM; INFANT; LIVER NEOPLASMS; MALE; REMISSION, SPONTANEOUS; THYROID HORMONES;

EID: 0346850815     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: 10.1542/peds.112.6.1424     Document Type: Article

References (10)

1. Huang SA, Tu HM, Harney JW, et al. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med. 2000;343:185-189
2. Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002;23:38-89
3. Nguyen L, Shandling B, Ein S, Stephens C. Hepatic hemangioma in childhood: medical management or surgical management? J Pediatr Surg. 1982;17:576-579
4. Richard K, Hume R, Kaptein E, et al. Ontogeny of iodothyronine deiodinases in human liver. J Clin Endocrinol Metab. 1998;83:2868-2874
5. Santini F, Chiovato L, Ghirri P, et al. Serum iodothyronines in the human fetus and the newborn: evidence for an important role of placenta in fetal thyroid hormone homeostasis. J Clin Endocrinol Metab. 1999;84:493-498
6. Boon LM, Burrows PE, Paltiel HJ, et al. Hepatic vascular anomalies in infancy: a twenty-seven-year experience. J Pediatr. 1996;129:346-354
7. Drolet BA, Esterly NB, Frieden IJ. Hemangiomas in children. N Engl J Med. 1999;341:173-181
8. Ayling RM, Davenport M, Hadzic N, et al. Hepatic hemangioendothelioma associated with production of humoral thyrotropin-like factor. J Pediatr. 2001;138:932-935
9. Huang SA, Fish SA, Dorfman DM, et al. A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. J Clin Endocrinol Metab. 2002;87:4457-4461
10. Song SI, Daneman D, Rovet J. The influence of etiology and treatment factors on intellectual outcome in congenital hypothyroidism. J Dev Behav Pediatr. 2001;22:376-384