Functional Characterization of Recombinant Myostatin and Its Inhibitory Role to Chicken Muscle Development

Acta Biochimica et Biophysica Sinica

Volumn 35, Issue 11, 2003, Pages 1016-1022

  Yang, Wei ^a   Wang, Kun ^a   Chen, Yan ^a   Zhang, Yong ^a   Huang, Bo ^a   Zhu, Da Hai ^b  

^a HARBIN INSTITUTE OF TECHNOLOGY   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Antibody production; Cellular localization; Differentiation; Myostatin; Proliferation

Indexed keywords

CELL MARKER; MYOGENIN; MYOSTATIN; POLYCLONAL ANTIBODY; PROTEIN ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CHICKEN; CYTOSOL; DOWN REGULATION; EMBRYO; FLOW CYTOMETRY; HUMAN; IMMUNOASSAY; IMMUNOFLUORESCENCE TEST; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; MOUSE; MUSCLE CELL; MUSCLE DEVELOPMENT; MYOBLAST; MYOTUBE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; RABBIT; RAT; WESTERN BLOTTING;

ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CHICK EMBRYO; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; HUMANS; MICE; MYOBLASTS; RATS; RECOMBINANT PROTEINS; TIME FACTORS;

ANIMALIA; GALLUS GALLUS; ORYCTOLAGUS CUNICULUS;

EID: 0346847627     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature, 1997, 387: 83-90
2. Grobet L, Martin LJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A et al. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat Gene, 1997, 17(1): 71 -74
3. Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, Sinha-Hikim I, Ma K, Ezzat S, Shen R et al. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci USA, 1998, 95(25): 14938-14943
4. Kawada S, Tachi C, Ishii N. Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading. J Muscle Res Cell Motil, 2001, 22(8): 627-633
5. Welle S, Bhatt K, Shah B, Thornton C. Insulin-like growth factor-1 and myostatin mRNA expression in muscle: Comparison between 62 -77 and 21-31 yr old men. Exp Gerontol, 2002, 37(6): 833-839
6. Joulia D, Bernardi H, Garandel V, Rabenoelina F, Vernus B, Cabello G. Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin. Exp Cell Res, 2003, 286(2): 263-275
7. Whittemore LA, Song K, Li X, Aghajanian J, Davies M, Girgenrath S, Hill JJ et al. Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem Biophys Res Commun, 2003, 300(4): 965-971
8. Bogdanovich S, Krag TO, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS. Functional improvement of dystrophic muscle by myostatin blockade. Nature, 2002, 420(6914): 418-421
9. Thomas M, Langley B, Berry C, Sharma M, Kirk S, Bass J, Kambadur R. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J Biol Chem, 2000, 275 (51): 40235-40243
10. Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, Kambadur R. Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem, 2002, 277(51): 49831-49840
11. Yang W, Wang HX, Chen Y, Zhang Y, Zhu DR Cloning, expression and purification of the chicken growth and differentiation factor-8. Chinese Journal of Biotechnology, 2001, 17(4): 460-462
12. Teruel T, Valverde AM, Navarro P, Benito M, Lorenzo M. Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes. J Cell Physiol, 1998, 176(1): 99-109
13. Buckingham M, Bajard L, Chang T, Daubas P, Hadchouel J, Meilhac S, Montarras D et al. The formation of skeletal muscle: From somite to limb. J Anat, 2003, 202(1): 59-68
14. Anderson JE, Garrett K, Moor A, McIntosh L, Penner K Dystrophy and myogenesis in max diaphragm muscle. Muscle Nerve, 1998, 21 (9): 1153-1165