Are anticonvulsants 'two thirds' of local anesthetics? A quantum pharmacology study

Journal of Molecular Structure: THEOCHEM

Volumn 638, Issue 1-3, 2003, Pages 57-62

  Carter, Michael D ^a   Stephenson, Vanessa C ^a   Weaver, Donald F ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Anticonvulsant; Density functional theory; Local anesthetics; Sodium channel

Indexed keywords

ANTICONVULSIVE AGENT; BENZOCAINE; CARBAMAZEPINE; CARBONYL DERIVATIVE; DIPHENYLOXAZOLIDINEDIONE; ETIDOCAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; OXYGEN; PHENOBARBITAL; PHENSUXIMIDE; PHENYL GROUP; PHENYLUREIDO DERIVATIVE; PHENYTOIN; PRILOCAINE; PROCAINAMIDE; PROCAINE; TETRACAINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCULATION; CHANNEL GATING; DENSITY FUNCTIONAL THEORY; DRUG CONFORMATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENERGY; HYPOTHESIS; PHARMACOPHORE; PROTEIN MOTIF; QUANTUM CHEMISTRY; SODIUM CHANNEL;

EID: 0346753951     PISSN: 01661280     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-1280(03)00542-6     Document Type: Article

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