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Volumn 88, Issue 1, 2004, Pages 161-168

The mechanism of membrane-translocation of regulator of G-protein signaling (RGS) 8 induced by Gα expression

Author keywords

Desensitization; G protein; G protein coupled receptor; Nuclear localization; Regulators of G protein signaling (RGS); Translocation

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA; GUANOSINE TRIPHOSPHATASE; RGS PROTEIN; RGS PROTEIN 8; UNCLASSIFIED DRUG;

EID: 0346733033     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02139.x     Document Type: Article
Times cited : (13)

References (29)
  • 1
    • 0031916822 scopus 로고    scopus 로고
    • Mammalian RGS proteins: Barbarians at the gate
    • Berman D. M. and Gilman A. G. (1998) Mammalian RGS proteins: barbarians at the gate. J. Biol. Chem. 273, 1269-1272.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1269-1272
    • Berman, D.M.1    Gilman, A.G.2
  • 2
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits
    • Berman D. M., Wilkie T. M. and Gilman A. G. (1996) GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86, 445-452.
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 3
    • 0020040057 scopus 로고
    • Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones
    • Chan R. K. and Otte C. A. (1982) Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones. Mol. Cell Biol. 2, 11-20.
    • (1982) Mol. Cell Biol. , vol.2 , pp. 11-20
    • Chan, R.K.1    Otte, C.A.2
  • 4
    • 0040142258 scopus 로고    scopus 로고
    • The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5
    • Chen C., Seow K. T., Guo K., Yaw L. P. and Lin S.-C. (1999) The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5. J. Biol. Chem. 274, 19799-19806.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19799-19806
    • Chen, C.1    Seow, K.T.2    Guo, K.3    Yaw, L.P.4    Lin, S.-C.5
  • 5
    • 0031041306 scopus 로고    scopus 로고
    • RGS proteins and signaling by heterotrimeric G proteins
    • Dohlman H. G. and Thomer J. (1997) RGS proteins and signaling by heterotrimeric G proteins. J. Biol. Chem. 272, 3871-3874.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3871-3874
    • Dohlman, H.G.1    Thomer, J.2
  • 6
    • 0030725498 scopus 로고    scopus 로고
    • Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins
    • Druey K. M. and Kehrl J. H. (1997) Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins. Proc. Natl Acad. Sci. USA 94, 12851-12856.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12851-12856
    • Druey, K.M.1    Kehrl, J.H.2
  • 7
    • 0030029727 scopus 로고    scopus 로고
    • Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family
    • Druey K. M., Blumer K. J., Kang V. H. and Kehrl J. H. (1996) Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature 379, 742-746.
    • (1996) Nature , vol.379 , pp. 742-746
    • Druey, K.M.1    Blumer, K.J.2    Kang, V.H.3    Kehrl, J.H.4
  • 10
    • 0035957996 scopus 로고    scopus 로고
    • Mechanisms governing subcellular localization and function of human RGS2
    • Heximer S. P., Lim H., Bernard J. L. and Blumer K. J. (2001) Mechanisms governing subcellular localization and function of human RGS2. J. Biol. Chem. 276, 14195-14203.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14195-14203
    • Heximer, S.P.1    Lim, H.2    Bernard, J.L.3    Blumer, K.J.4
  • 11
    • 0030610240 scopus 로고    scopus 로고
    • Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells
    • Huang C., Hepler J. R., Gilman A. G. and Mumby S. M. (1997) Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells. Proc. Natl Acad. Sci. USA 94, 6159-6163.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6159-6163
    • Huang, C.1    Hepler, J.R.2    Gilman, A.G.3    Mumby, S.M.4
  • 12
    • 0029830014 scopus 로고    scopus 로고
    • RGS10 is a selective activator of G alpha i GTPase activity
    • Hunt T. W., Fields T. A., Casey P. J. and Peralta E. G. (1996) RGS10 is a selective activator of G alpha i GTPase activity. Nature 383, 175-177.
    • (1996) Nature , vol.383 , pp. 175-177
    • Hunt, T.W.1    Fields, T.A.2    Casey, P.J.3    Peralta, E.G.4
  • 13
    • 0342351738 scopus 로고
    • Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain
    • Itoh H., Kozasa T., Nagata S., Nakamura S., Katada T., Ui M., Iwai S., Ohtsuka E., Kawasaki H., Suzuki K. et al. (1986) Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proc. Natl Acad. Sci. USA 83, 3776-3780.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3776-3780
    • Itoh, H.1    Kozasa, T.2    Nagata, S.3    Nakamura, S.4    Katada, T.5    Ui, M.6    Iwai, S.7    Ohtsuka, E.8    Kawasaki, H.9    Suzuki, K.10
  • 14
    • 0023887079 scopus 로고
    • Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs
    • Itoh H., Toyama R., Kozasa T., Tsukamoto T., Matsuoka M. and Kaziro Y. (1988) Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs. J. Biol. Chem. 263, 6656-6664.
    • (1988) J. Biol. Chem. , vol.263 , pp. 6656-6664
    • Itoh, H.1    Toyama, R.2    Kozasa, T.3    Tsukamoto, T.4    Matsuoka, M.5    Kaziro, Y.6
  • 15
    • 0035860244 scopus 로고    scopus 로고
    • RGS8 protein is distributed in dendrites and cell body of cerebellar Purkinje cell
    • Itoh M., Odagiri M., Abe H. and Saitoh O. (2001) RGS8 protein is distributed in dendrites and cell body of cerebellar Purkinje cell. Biochem. Biophys. Res. Comm. 287, 223-228.
    • (2001) Biochem. Biophys. Res. Comm. , vol.287 , pp. 223-228
    • Itoh, M.1    Odagiri, M.2    Abe, H.3    Saitoh, O.4
  • 16
    • 0030032001 scopus 로고    scopus 로고
    • EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins
    • Koelle M. R. and Horvitz H. R. (1996) EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell 84, 115-125.
    • (1996) Cell , vol.84 , pp. 115-125
    • Koelle, M.R.1    Horvitz, H.R.2
  • 18
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa H., Yamamura K. and Miyazaki J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-200.
    • (1991) Gene , vol.108 , pp. 193-200
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 23
    • 0037162557 scopus 로고    scopus 로고
    • Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling
    • Saitoh O., Murata Y., Odagiri M., Itoh M., Itoh H., Misaka T. and Kubo Y. (2002) Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling. Proc. Natl Acad. Sci. USA 99, 10138-10143.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10138-10143
    • Saitoh, O.1    Murata, Y.2    Odagiri, M.3    Itoh, M.4    Itoh, H.5    Misaka, T.6    Kubo, Y.7
  • 24
    • 0032510737 scopus 로고    scopus 로고
    • Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae
    • Srinivasa S. P., Bernstein L. S., Blumer K. J. and Linder M. E. (1998) Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 95, 5584-5589.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5584-5589
    • Srinivasa, S.P.1    Bernstein, L.S.2    Blumer, K.J.3    Linder, M.E.4
  • 25
    • 0029808079 scopus 로고    scopus 로고
    • RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits
    • Watson N., Linder M. E., Druey K. M., Kehrl J. H. and Blumer K. J. (1996) RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature 383, 172-175,
    • (1996) Nature , vol.383 , pp. 172-175
    • Watson, N.1    Linder, M.E.2    Druey, K.M.3    Kehrl, J.H.4    Blumer, K.J.5
  • 26
    • 0030784775 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors
    • Yamauchi J., Nagao M., Kaziro Y. and Itoh H. (1997) Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. J. Biol. Chem. 272, 27771-27777.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27771-27777
    • Yamauchi, J.1    Nagao, M.2    Kaziro, Y.3    Itoh, H.4
  • 27
  • 28
    • 0030611749 scopus 로고    scopus 로고
    • RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis
    • Yan Y., Chi P. P. and Bourne B. (1997) RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis. J. Biol. Chem. 272, 11924-11927.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11924-11927
    • Yan, Y.1    Chi, P.P.2    Bourne, B.3
  • 29
    • 0035912846 scopus 로고    scopus 로고
    • Heteromeric association creates a P2Y-like adenosine receptor
    • Yoshioka K., Saitoh O. and Nakata H. (2001) Heteromeric association creates a P2Y-like adenosine receptor. Proc. Natl Acad. Sci. USA 98, 7617-7622.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7617-7622
    • Yoshioka, K.1    Saitoh, O.2    Nakata, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.