Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase

FEBS Letters

Volumn 556, Issue 1-3, 2004, Pages 43-46

  Kinoshita, Takayoshi ^a   Nakanishi, Isao ^a,b   Warizaya, Masaichi ^a   Iwashita, Akinori ^a   Kido, Yoshiyuki ^a   Hattori, Kouji ^a   Fujii, Takashi ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Crystal structure; Inhibitor induced; Molecular molecular interaction; Poly(ADP ribose) polymerase; Structural change; Synchrotron radiation

Indexed keywords

FR 257517; ISOLEUCINE; LEUCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PROLINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HUMAN; HYDROPHOBICITY; MOLECULAR INTERACTION; PRIORITY JOURNAL;

ZEA MAYS;

EID: 0346725042     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(03)01362-0     Document Type: Article

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