Role of potassium channels in the nitric oxide-independent vasodilator response to acetylcholine

Pharmacological Research

Volumn 49, Issue 3, 2004, Pages 207-215

  Dabisch, Paul A ^a   Liles, John T ^a   Taylor, James T ^a   Sears, Benjamin W ^a   Saenz, Rodrigo ^a   Kadowitz, Philip J ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Acetylcholine; Cyclooxygenase; Nitric oxide; Potassium channels

Indexed keywords

3,4 DIHYDRO 2,2 DIMETHYL 4 (2 OXO 1 PIPERIDINYL) 6 PENTAFLUOROETHYL 2H 1 BENZOPYRAN 3 OL; ACETYLCHOLINE; APAMIN; CHARYBDOTOXIN; MECLOFENAMIC ACID; N (1 ADAMANTYL) N' CYCLOHEXYL 4 MORPHOLINECARBOXAMIDINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; HINDLIMB; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; VASODILATATION;

EID: 0346690096     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2003.09.010     Document Type: Article

References (39)

1. Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 288:1980;373-376.
2. Furchgott R.F., Carvalho M.H., Khan M.T., Matsunaga K. Evidence for endothelium-dependent vasodilation of resistance vessels by acetylcholine. Blood Vessels. 24:1987;145-149.
3. ω-nitro-L-arginine selectively inhibits vasodilator responses to acetylcholine and bradykinin in cats. Am. J. Physiol. 260:1991;1025-1029.
4. Broten T.P., Miyashiro J.K., Moncada S., Feigl E.O. Role of endothelium-derived relaxing factor in parasympathetic coronary vasodilation. Am. J. Physiol. 262:1992;1579-1584.
5. Ignarro L.J., Byrns R.E., Buga G.M., Wood K.S. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ. Res. 61:1987;866-879.
6. Ignarro L.J., Buga G.M., Byrns R.E., Wood K.S., Chaudhuri G. Endothelium-derived relaxing factor and nitric oxide possess identical pharmacologic properties as relaxants of bovine arterial and venous smooth muscle. J. Pharmacol. Exp. Ther. 246:1988;218-226.
7. Ignarro L.J., Byrns R.E., Buga G.M., Wood K.S., Chaudhuri G. Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium- dependent and nitric oxide-elicited vascular smooth muscle relaxation. J. Pharmacol. Exp. Ther. 244:1988;181-189.
8. Huang A.N., Sun D., Smith C.J., Connetta J.A., Shesely E.G., Koller K.et al. In eNOS knockout mice skeletal muscle arteriolar dilation to acetylcholine is mediated by EDHF. Am. J. Physiol. 278:2000;762-768.
9. Ross G., Chaudhuri G., Ignarro L.J., Chyu K.Y. Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide. Eur. J. Pharmacol. 195:1991;291-293.
10. Waldron G.J., Ding H., Lovren F., Kubes P., Triggle C.R. Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase. Br. J. Pharmacol. 128:1999;653-658.
11. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature. 396:1998;269-272.
12. Beny J.L. Electrical coupling between smooth muscle cells and endothelial cells in pig coronary arteries. Pflugers Arch. 433:1997;364-367.
13. Goto K., Fujii K., Kansui Y., Abe I., Iida M. Critical role of gap junctions in endothelium-dependent hyperpolarization in rat mesenteric arteries. Clin. Exp. Pharmacol. Phys. 29:2000;595-602.
14. Sandow S.L., Tare M., Coleman H.A., Hill C.E., Parkington H.C. Involvement of myoendothelial gap junctions in the actions of endothelium derived hyperpolarizing factor. Circ. Res. 90:2002;1108-1113.
15. Ca channels and elicit EDHF-type arteriolar dilation via gap junctions. Am. J. Physiol. 282:2002;1760-1767.
16. Kakoki M., Zou A., Mattson D.L. The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am. J. Physiol. 281:2001;91-97.
17. ω- nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin. J. Appl. Physiol. 71:1991;2026-2031.
18. Rees D.D., Palmer R.M.J., Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. 86:1989;3375-3378.
19. Rees D.D., Palmer R.M.J., Schulz R., Hodson H.F., Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101:1990;746-752.
20. Jancso T., Rabloczky G., Csukas M. Examination of the law of initial value in connection with the blood pressure response of anaesthetized and non-anaesthetized cats. Acta Physiol. Acad. Sci. Hung. 42:1972;333-343.
21. Aisaka K., Gross S.S., Griffith O.W., Levi R. L-Arginine availability determines the duration of acetylcholine-induced systemic vasodilatation in vivo. Biochem. Biophys. Res. Commun. 163:1989;710-717.
22. Bellan J.A., Longnecker L.L., Kadowitz P.J., McNamara D.B. Selective and complete blockade of acetylcholine-induced relaxation in rabbit aortic rings by N-omega-nitro-L-arginine but not by glybenclamide. Eur. J. Pharm. 234:1993;273-276.
23. Champion H.C., Bivalacqua T.J., Zadina J.E., Kastin A.J., Hyman A.L., Kadowitz P.J. Role of nitric oxide in mediating vasodilator responses to opioid peptides in the rat. Clin. Exp. Pharmacol. Physiol. 29:2002;229-232.
24. Parkington H.C., Chow J.M., Evans R.G., Coleman H.A., Tare M. Role for endothelium-derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo. J. Physiol. 542:2002;929-937.
25. Whittle B.J.R., Lopez-Belmonte J., Rees D.D. Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P, and endothelin in the rat by a specific inhibitor of nitric oxide formation. Br. J. Pharmacol. 98:1989;646-652.
26. Feitelson J.B.A., Kulenovic E., Beck D.J., Harris P.D., Passmore J.C., Malkani A.L.et al. Endogenous norepinephrine regulates blood flow to the intact rat tibia. J. Orthop. Res. 20:2002;391-396.
27. Brock R.W., Tschakovsky M.E., Shoemaker J.K., Halliwill J.R., Joyner M.J., Hughson R.L. Effects of acetylcholine and nitric oxide on forearm blood flow at rest and after a single muscle contraction. J. Appl. Physiol. 85:1998;2249-2254.
28. Cohen R.A., Plane F., Najibi S., Huk I., Malinski T., Garland C.J. Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery. Proc. Natl. Acad. Sci. 94:1997;4193-4198.
29. ω-nitro-L- arginine in rats. Am. J. Physiol. 263:1992;1090-1094.
30. Doughty J.M., Plane F., Langton P.D. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. Am. J. Physiol. 276:1999;1107-1112.
31. McIntyre C.A., Buckley C.H., Jones G.C., Sandeep T.C., Andrews R.C., Elliott A.I.et al. Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries. Br. J. Pharmacol. 133:2001;902-908.
32. Wigg S.J., Tare M., Tonta M.A., O'Brien R.C., Meredith I.T., Parkington H.C. Comparison of effects of diabetes mellitus on an EDHF-dependent and an EDHF-independent artery. Am. J. Physiol. 281:2001;232-240.
33. + channel openers on relaxations to nitric oxide and endothelium-derived hyperpolarizing factor in rat mesenteric artery. Eur. J. Pharmacol. 357:1998;41-51.
34. + channels in arterial smooth muscle. Science. 245:1989;177-180.
35. 2 on membrane potential of smooth muscle cells in rabbit mesenteric resistance artery. Eur. J. Pharmacol. 464:2003;101-109.
36. Brayden J.E. Functional roles of KATP channels in vascular smooth muscle. Clin. Exp. Pharmacol. Physiol. 29:2002;312-316.
37. Plane F., Wiley K.E., Jeremy J.Y., Cohen R.A., Garland C.J. Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery. Br. J. Pharmacol. 123:1998;1351-1358.
38. Scotland R.S., Chauman S., Vallance P.J., Ahluwalia A. An endothelium-derived hyperpolarizing factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide. Hypertension. 38:2001;833-839.
39. Morio Y., Carter E.P., Oka M., McMurtry I.F. EDHF-mediated vasodilation involves different mechanisms in normotensive and hypertensive rat lungs. Am. J. Physiol. 284:2003;1762-1770.