Detection of COX-1 and COX-2 isoforms in synovial fluid cells from inflammatory joint diseases

British Journal of Rheumatology

Volumn 37, Issue 7, 1998, Pages 773-778

  Iniguez M A ^a   Pablos, J L ^a   Carreira, P E ^a   Cabre F ^b   Gomez Reino, J J ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b Laboratorios Menarini SA   (Spain)

Author keywords

Cyclooxygenases; Prostaglandins; Rheumatoid arthritis

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MESSENGER RNA;

ARTHRITIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LEUKOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIATIC ARTHRITIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

EID: 0346401094     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/37.7.773     Document Type: Article

References (23)

1. Davies P, Bailey PJ, Goldenberg MM, Ford-Hutchinson AW. The role of arachidonic acid oxygenation products in pain and inflammation. Annu Rev Immunol 1984; 2:335-57.
2. Robinson DR, McGuire MB, Levine L. Prostaglandins in the rheumatic diseases. Ann NY Acad Sci 1975; 256:318-29.
3. Sano H, Hla T, Maier JAM, Crofford L, Case JP, Maciag T et al. In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. J Clin Invest 1992;89:97-108.
4. Geng Y, Blanco FJ, Cornelisson M, Lotz M. Regulation of cyclooxygenase-2 expression in normal human articular chondrocytes. J Immunol 1995;155:796-801.
5. Funk CD, Funk LB, Kennedy ME, Pong AS, Fitzgerald GA. Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J 1991;5:2304-12.
6. Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 1991;266:12866-72.
7. Lee SH, Soyoola E, Chanmugam P, Hart S, Sun W, Zhong H et al. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J Biol Chem 1992;267:25934-8.
8. Crofford LJ, Wilder RL, Ristimaki AP, Sano H, Remmers EF, Epps HR et al. Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 1994;93:1095-101.
9. Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory S. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996;97:2672-9.
10. Amin AR, Attur M, Patel RN, Thakker G, Marshall PJ, Rediske J et al. Superinduction of cyclooxygenase activity in human osteoarthritis-affected cartilage. J Clin Invest 1997;99:1231-7.
11. Dinchuk JE, Car BD, Focht RJ, Johnston JJ, Jaffee BD, Covington MB et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995;378:406-9.
12. Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995;83:483-92.
13. Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC et al. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 1995;83:473-82.
14. Bozza PT, Payne JL, Morham SG, Langenbach R, Smithies O, Weller PF. Leukocyte lipid body formation and eicosanoid generation: Cyclooxygenase-independent inhibition by aspirin. Proc Natl Acad Sci USA 1996;93:11091-6.
15. Wilborn J, DeWitt DL, Peters-Golden M. Expression and role of cyclooxygenase isoforms in alveolar and peritoneal macrophages. Am J Physiol 1995;268(2 part 1):L294-301.
16. Netter P, Bannwarth B, Lapicquel F, Demotes-Mainard F, Schceverbeke T, Gillet P. Pharmacokinetics and pharmacodynamics of non steroidal anti-inflammatory drugs in synovial fluid. Agents Actions 1993;44(suppl.):45-50.
17. Masferrer JL, Zweiffel BS, Manning PT, Hauser SD, Leahy KM, Smith WG et al. Selective inhibition of inducible cyclooxygenase 2 in vitro is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci USA 1994; 91:3228-32.
18. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
19. Evett GE, Xie W, Chipman JG, Robertson DL, Simmons DL. Prostaglandin G/H synthase isoenzyme 2 expression in fibroblasts: regulation by dexamethasone, mitogens and oncogenes. Arch Biochem Biophys 1993;306:169-77.
20. Hoff T, DeWitt D, Kaever V, Resch K, Coppelt-Struebe M. Differentiation associated expression of prostaglandin G/H synthase in monocytic cells. FEBS Lett 1993; 320:38-42.
21. Smith CJ, Morrow JD, Roberts LJ, Marnett LJ. Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). Biochem Biophys Res Commun 1993;192:787-93.
22. Brannon TS, North AJ, Wells LB, Shaul PW. Prostacyclin synthesis in ovine pulmonary artery is developmentally regulated by changes in cyclooxygenase-1 gene expression. J Clin Invest 1994;93:2230-5.
23. Vane JR. Towards a better aspirin. Nature 1994; 367:215-6.