Localization and expression of thyroid hormone receptors in normal and neoplastic human thyroid

Journal of Endocrinological Investigation

Volumn 26, Issue 10, 2003, Pages 1008-1012

  Crescenzi, A ^a   Graziano, M F ^b   Carosa, E ^c   Papini, E ^a   Rucci, N ^c   Nardi, F ^b   Trimboli, P ^b   Calvanese, A ^b   Jannini, E A ^c   D'Armiento, Massimino ^b  

^a Institute Regina Apostolorum   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

Thyroid gland; Thyroid receptor; Tumors

Indexed keywords

MESSENGER RNA; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR ALPHA1; THYROID HORMONE RECEPTOR ALPHA2; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA2; UNCLASSIFIED DRUG;

ADULT; ANAPLASTIC CARCINOMA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENSITOMETRY; FEMALE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID ADENOMA; THYROID CARCINOMA; THYROID CELL; THYROID FOLLICULAR CARCINOMA; THYROID GLAND; THYROID PAPILLARY CARCINOMA; THYROID SURGERY; THYROID TUMOR; TUMOR DIFFERENTIATION;

EID: 0346368467     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03348200     Document Type: Article

References (23)

1. Weinberger C, Thopson CC, Ong ES, Lebo R, Gruol DJ, Evans RM. The c-erb-A gene encodes a thyroid hormone receptor. Nature 1986, 324: 641-6.
2. Sap J, Munoz A, Damm K, et al. The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature 1986, 324: 635-40.
3. Tomura H, Lazar J, Phyillaier M, Nikoderm VM. The N-terminal region (A/B) of rat thyroid hormone receptors alpha 1, beta 1, but not beta 2 contains a strong thyroid hormone-dependent transactivation function. Proc Natl Acad Sci USA 1995, 92: 5600-4.
4. Wallin G, Bronnegard M, Grimelius L, McGuire J, Torring O. Expression of the thyroid hormone receptor, the oncogenes c-myc and H-ras, and the 90 kD heat shock protein in normal, hyperplastic, and neoplastic thyroid tissue. Thyroid 1992, 2: 307-17.
5. Nakai A, Sakurai A, Bell GI, De Groot LJ. Characterization of a third human thyroid hormone receptor coexpressed with other thyroid hormone receptors in several tissues. Mol Endocrinol 1988, 2: 1087-92.
6. Macchia E, Nakai A, Janiga A, et al. Characterization of site-specific polyclonal antibodies to c-erbA peptides recognizing human thyroid hormone receptors α1, α2 and β and native 3,5,3′-triiodothyronine receptor, and study of tissue distribution of the antigen. Endocrinology 1990, 126: 3232-9.
7. Bronnegard M, Torring O, Boos J, Sylven C, Marcus C, Wallin G. Expression of thyrotropin receptor and thyroid hormone receptor messenger ribonucleic acid in normal hyperplastic, and neoplastic human thyroid tissue. J Clin Endocrinol Metab 1994, 79: 384-9.
8. Selmi-Ruby S, Rousset B. Analysis of the functional state of T3 nuclear receptor expressed in thyroid cells. Mol Cell Endocrinol 1996, 119: 95-104.
9. Akiguchi I, Strauss K, Borges M, Silva JE., Moses AC. Thyroid hormone receptors and 3,5,3′-triiodothyronine biological effects in FRTL5 thyroid follicular cell. Endocrinology 1992, 131: 1279-87.
10. Nagy N, Camby I, Decaestecker C, et al. The influence of L-triiodothyronine, L-thyroxine, estradiol-17β, the luteinizing-hormone-releasing hormone, the epidermal growth factor and gastrin on cell proliferation in organ cultures of 35 benign and 13 malignant human thyroid tumors. J Cancer Res Clin Oncol 1999, 125: 361-8.
11. Di Fulvio M, Coleoni AH, Pellizas CG, Masini-Repiso AM. Triidothyronine induces proliferation in cultured bovine thyroid cells: Evidence for the involvement of epidermal growth factor-associated tyrosine kinase activity. J Endocrinol 2000, 166: 173-82.
12. Gauthier K, Chassande MP, Roux JP, et al. Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post-natal development. EMBO J 1999, 18: 623-31.
13. Forrest D, Hanebuth E, Smeyne RJ, et al. Recessive resistance to thyroid hormone in mice laking thyroid hormone receptor β: Evidence for tissue-specific modulation of receptor function. EMBO J 1996, 15: 3006-15.
14. Chen ST, Shieh HY, Lin JD, Chang KS, Lin KH. Overexpression of thyroid hormone receptor beta1 is associated with thyrotropin receptor gene expression and proliferation in a human thyroid carcinoma cell line. J Endocrinol 2000, 165: 379-89.
15. Elisei R, Pinchera A, Romei C, et al. Expression of thyrotropin receptor (TSH-R), thyroglobulin, thyroperoxidase, and calcitonin messenger ribonucleic acids in thyroid carcinomas: Evidence of TSH-R gene transcript in medullary histotype. J Clin Endocrinol Metab 1994, 78: 867-71.
16. Christensen L, Blichert-Toft M, Brandt M, et al. Thyroperoxidase (TPO) immunostaining of the solitary cold thyroid nodule. Clin Endocrinol (Oxf) 2000, 53: 161-9.
17. Bejarano PA, Nikiforov YE, Swenson ES, Biddinger PW. Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms. Appl Immunohistochem Mol Morphol 2000, 8: 189-94.
18. Chomzynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987, 162: 156-9.
19. Thompson CC, Weinberger C, Lebo R, Evans RM. Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science 1987, 237: 1610-4.
20. Arcari P, Martinelli R, Salvatore F. The complete sequence of a full length cDNA for human liver glyceraldehydes-3-phospate dehydrogenase: Evidence for multiple mRNA species. Nucleic Acid Res 1984, 12: 9179-89.
21. Jannini EA, Crescenzi A, Rucci N, et al. Ontogenetic pattern of thyroid hormone receptor expression in the human testis. J Clin Endocrinol Metab 2000, 85: 3453-7.
22. Fraichard A, Chassande O, Plateroti M, et al. The T3 R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production. EMBO J 1997, 16: 4412-20.
23. Koenig RJ, Lazar MA, Hodin RA, et al. Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature 1989, 337: 659-61.