-
1
-
-
0000725690
-
Topical and in vitro pharmacology of tepoxalin: A new dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor
-
ARGENTIERI, D. C. et al.: Topical and in vitro pharmacology of tepoxalin: A new dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor. FASEB J. 2, A369 (1988).
-
(1988)
FASEB J.
, vol.2
-
-
Argentieri, D.C.1
-
2
-
-
0001700112
-
Tepoxalin (RWJ 20485) inhibits prostaglandin (PG) and leukotriene (LT) production in adjuvant arthritic rats and in dog knee joints challenged with sodium urate and immune complexes
-
ARGENTIERI, D. C., D. W. ANDERSON, D. M. RITCHIE, M. E. ROSENTHALE und R. J. CAPETOLA: Tepoxalin (RWJ 20485) inhibits prostaglandin (PG) and leukotriene (LT) production in adjuvant arthritic rats and in dog knee joints challenged with sodium urate and immune complexes. FASEB J. 4, A1122 (1990).
-
(1990)
FASEB J.
, vol.4
-
-
Argentieri, D.C.1
Anderson, D.W.2
Ritchie, D.M.3
Rosenthale, M.E.4
Capetola, R.J.5
-
3
-
-
0028170934
-
Tepoxalin: A dual cyclooxygenase/5-Lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile
-
ARGENTIERI, D. C. et al.: Tepoxalin: a dual cyclooxygenase/5-Lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile. J. Pharmacol. Exp. Ther., 271, 1399-1408 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 1399-1408
-
-
Argentieri, D.C.1
-
4
-
-
0346389963
-
Pulmonary and anti-inflammatory profile of tepoxalin, a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor
-
CAPETOLA, R. J. et al.: Pulmonary and anti-inflammatory profile of tepoxalin, a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor. FASEB J. 2, A369 (1988).
-
(1988)
FASEB J.
, vol.2
-
-
Capetola, R.J.1
-
5
-
-
0017848695
-
1-Phenyl-3 pyrazolidone: An inhibitor of arachidonate oxidation in lung and platelets
-
BLACKWELL, G. J. und R. J. FLOWER: 1-Phenyl-3 pyrazolidone: An inhibitor of arachidonate oxidation in lung and platelets. Br. J. Pharmacol. 63, 360 (1978).
-
(1978)
Br. J. Pharmacol.
, vol.63
, pp. 360
-
-
Blackwell, G.J.1
Flower, R.J.2
-
6
-
-
0032782290
-
The non-steroidal antiinflammatory drug tepoxalin inhibits interleukin-6 and alpha1-anti- Chymotrypsin synthesis in astrocytes by preventing degradation of IκB-alpha
-
FIEBICH, B. L., T. J. HOFER, K. LIEB, M. HUELL, R. D. BUTCHER, G. SCHUMANN, K. SCHULZEOSTHOFF und J. BAUER: The non-steroidal antiinflammatory drug tepoxalin inhibits interleukin-6 and alpha1-anti-chymotrypsin synthesis in astrocytes by preventing degradation of IκB-alpha. Neuropharmacology, 38, 1325-1333 (1999).
-
(1999)
Neuropharmacology
, vol.38
, pp. 1325-1333
-
-
Fiebich, B.L.1
Hofer, T.J.2
Lieb, K.3
Huell, M.4
Butcher, R.D.5
Schumann, G.6
Schulzeosthoff, K.7
Bauer, J.8
-
8
-
-
0031034254
-
Review: A classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes
-
FRÖLICH, J. C.: Review: a classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes. Trends pharmacol. Sci. 18, 30-34 (1997).
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 30-34
-
-
Frölich, J.C.1
-
9
-
-
0029161849
-
Tepoxalin, a novel immunomodulatory compound, synergizes with CSa in suppression of graftversus-host reaction and allogeneic skin graft rejection
-
FUNG-LEUNG, W.-P., B. L. POPE, E. CHOURMOUZIS, J. A. PANAKOS und C. Y. LAU: Tepoxalin, a novel immunomodulatory compound, synergizes with CSA in suppression of graftversus-host reaction and allogeneic skin graft rejection. Transplantation 60, 362-368 (1995).
-
(1995)
Transplantation
, vol.60
, pp. 362-368
-
-
Fung-Leung, W.-P.1
Pope, B.L.2
Chourmouzis, E.3
Panakos, J.A.4
Lau, C.Y.5
-
10
-
-
0031900663
-
Treatment methods for pain in the osteoarthritic patient
-
HULSE, D.: Treatment methods for pain in the osteoarthritic patient. Clin. Pharmcol. Ther. 28, 361-375 (1998).
-
(1998)
Clin. Pharmcol. Ther.
, vol.28
, pp. 361-375
-
-
Hulse, D.1
-
11
-
-
0028795227
-
Suppression of NFκB activation and NF κB-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase
-
KAZMI, S. M. I., R. K. PLANTE, V. VISCONTI, G. R. TAYLOR, L. ZHOU und C. Y. LAU: Suppression of NFκB activation and NF κB-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase. J. Cell Biochem., 57, 299-310 (1995).
-
(1995)
J. Cell Biochem.
, vol.57
, pp. 299-310
-
-
Kazmi, S.M.I.1
Plante, R.K.2
Visconti, V.3
Taylor, G.R.4
Zhou, L.5
Lau, C.Y.6
-
12
-
-
0030910191
-
Effects of tepoxalin, a dualinhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation
-
KIRCHNER, T., B. APARICIO, D. C. ARGENTIERI, C. Y. LAU und D. M. RITCHIE: Effects of tepoxalin, a dualinhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation. Prostaglandins Leukot, Essent Fatty Acids, 56, 417-423 (1997).
-
(1997)
Prostaglandins Leukot, Essent Fatty Acids
, vol.56
, pp. 417-423
-
-
Kirchner, T.1
Aparicio, B.2
Argentieri, D.C.3
Lau, C.Y.4
Ritchie, D.M.5
-
13
-
-
26844582574
-
Preclinical toxicity evaluation of tepoxalin, a dual inhibitor of cyclooxygenase und 5-Lipoxygenase, in Sprague-Dawley rats and beagle dogs
-
KNIGHT, E. V., J. P. KIMBALL, C. M. KEENAN, I. L. SMITH, F. A. WONG, D. S. BARRETT, A. M. DEMPSTER, W. G. LIEUALLEN, D. PANIGRAHI, W. J. POERS und R. J. SZOT: Preclinical toxicity evaluation of tepoxalin, a dual inhibitor of cyclooxygenase und 5-Lipoxygenase, in Sprague-Dawley rats and beagle dogs. Fundam. Appl. Toxicol. 33, 38-48 (1996).
-
(1996)
Fundam. Appl. Toxicol.
, vol.33
, pp. 38-48
-
-
Knight, E.V.1
Kimball, J.P.2
Keenan, C.M.3
Smith, I.L.4
Wong, F.A.5
Barrett, D.S.6
Dempster, A.M.7
Lieuallen, W.G.8
Panigrahi, D.9
Poers, W.J.10
Szot, R.J.11
-
14
-
-
0022033332
-
Clinical pharmacology and therapeutic uses of nonsteroidal antiinflammatory drugs in the horse
-
LEES, P. und A. J. HIGGINS: Clinical pharmacology and therapeutic uses of nonsteroidal antiinflammatory drugs in the horse. Equine Vet. J. 17, 83-96 (1985).
-
(1985)
Equine Vet. J.
, vol.17
, pp. 83-96
-
-
Lees, P.1
Higgins, A.J.2
-
15
-
-
0025164256
-
Leukotrienes and other products of the 5-lipoxygenase pathway: Biochemistry and relation of pathobiology in human diseases
-
LEWIS, R. A., K. F. AUSTEN und R. J. SOBERMAN: Leukotrienes and other products of the 5-lipoxygenase pathway: Biochemistry and relation of pathobiology in human diseases. N. Engl. J. Med. 323, 645 (1990).
-
(1990)
N. Engl. J. Med.
, vol.323
, pp. 645
-
-
Lewis, R.A.1
Austen, K.F.2
Soberman, R.J.3
-
16
-
-
0026600085
-
Endothelin induces vascular and mucosal lesions, enhances the injury by HCl/ethanol, and the antibody exerts gastroprotection
-
MORALES, R. E., B. R. JOHNSON und S. SZABO: Endothelin induces vascular and mucosal lesions, enhances the injury by HCl/ethanol, and the antibody exerts gastroprotection. FASEB J., 6, 2354 (1992).
-
(1992)
FASEB J.
, vol.6
, pp. 2354
-
-
Morales, R.E.1
Johnson, B.R.2
Szabo, S.3
-
17
-
-
0347650718
-
Cytokine modulation by tepoxalin-a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor with potential antirheumatic activity
-
Wien
-
RITCHIE, D. M., D. C. ARGENTIERI, C. LAU und A. G. BARBONE: Cytokine modulation by tepoxalin-a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor with potential antirheumatic activity. Abstract book world congress inflammation, Wien (1993).
-
(1993)
Abstract Book World Congress Inflammation
-
-
Ritchie, D.M.1
Argentieri, D.C.2
Lau, C.3
Barbone, A.G.4
-
18
-
-
0028829414
-
Cytokine modulation by tepoxalin, a new potential antirheumatic
-
RITCHIE, D. M., D. C. ARGENTIERI, B. L. APARICIO, R. K. PLANTE, C. Y. LAU und A. G. BARBONE: Cytokine modulation by tepoxalin, a new potential antirheumatic. Int. J. Immunopharmac., 17, 805-812 (1995).
-
(1995)
Int. J. Immunopharmac.
, vol.17
, pp. 805-812
-
-
Ritchie, D.M.1
Argentieri, D.C.2
Aparicio, B.L.3
Plante, R.K.4
Lau, C.Y.5
Barbone, A.G.6
-
19
-
-
0028012449
-
Differential interactions of prostaglandin endoperoxide synthases with nonsteroidal anit-inflammatory drugs
-
SMITH, W. L. und D. L. DeWITT: Differential interactions of prostaglandin endoperoxide synthases with nonsteroidal anit-inflammatory drugs. Curr. Opin. Invest. Drugs 3, 1-11 (1994).
-
(1994)
Curr. Opin. Invest. Drugs
, vol.3
, pp. 1-11
-
-
Smith, W.L.1
DeWitt, D.L.2
-
20
-
-
0028044609
-
Towards a better aspirin
-
VANE, J. R.: Towards a better aspirin. Nature 367, 215-216 (1994).
-
(1994)
Nature
, vol.367
, pp. 215-216
-
-
Vane, J.R.1
-
21
-
-
0030921942
-
The pathophysiology and medical management of canine osteoarthritis
-
VAUGHAN-SCOTT, T. und J. H. TAYLOR.: The pathophysiology and medical management of canine osteoarthritis. JI S. Afr. vet. Ass. 68, 21-25 (1997).
-
(1997)
JI S. Afr. Vet. Ass.
, vol.68
, pp. 21-25
-
-
Vaughan-Scott, T.1
Taylor, J.H.2
-
22
-
-
9344250076
-
Pharmacokinetics and pharmacodynamics of Tepoxalin after single oral dose administration to healthy volunteers
-
WALDMANN, S. A., C. VITOW, B. OSBORNE, L. GILLEN, D. C. ARGENTIERI, F. A. WONG, I. L. SMITH, A. CHOW, J. MISITI und T. D. BJORNSONN: Pharmacokinetics and pharmacodynamics of Tepoxalin after single oral dose administration to healthy volunteers. J. Clin. Pharmacol., 36, 462-468 (1996).
-
(1996)
J. Clin. Pharmacol.
, vol.36
, pp. 462-468
-
-
Waldmann, S.A.1
Vitow, C.2
Osborne, B.3
Gillen, L.4
Argentieri, D.C.5
Wong, F.A.6
Smith, I.L.7
Chow, A.8
Misiti, J.9
Bjornsonn, T.D.10
-
23
-
-
0027141933
-
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxlin: Anti-inflammatory without gastropathy?
-
WALLACE, J. L., D.-M. McCAFFERTY, L. CARTER, W. McKNIGHT und D. ARGENTIERI.: Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxlin: anti-inflammatory without gastropathy? Gastroenterology, 105, 1630-1636 (1993).
-
(1993)
Gastroenterology
, vol.105
, pp. 1630-1636
-
-
Wallace, J.L.1
McCafferty, D.-M.2
Carter, L.3
McKnight, W.4
Argentieri, D.5
-
24
-
-
0031871408
-
Antiinflammatory effect of tepoxalin: Blood and synovial tissue studied in patients with knee arthrosis
-
WILLBURGER, R. E., R. H. WITTENBERG, K. SCHMIDT, K. S. KLEEMEYER und B. A. PESKAR: Antiinflammatory effect of tepoxalin: blood and synovial tissue studied in patients with knee arthrosis. Acta Orthop. Scand. 69, 295-300 (1998).
-
(1998)
Acta Orthop. Scand.
, vol.69
, pp. 295-300
-
-
Willburger, R.E.1
Wittenberg, R.H.2
Schmidt, K.3
Kleemeyer, K.S.4
Peskar, B.A.5
-
25
-
-
0030061092
-
Tepoxalin blocks neutrophil migration into cutaneous inflammatory sites by inhibiting Mac-1 and E-selectin expression
-
ZHOU, L, B. L. POPE, E. ChOURMOUZIS, W.-P. FUNG-LEUNG und C. Y. LAU: Tepoxalin blocks neutrophil migration into cutaneous inflammatory sites by inhibiting Mac-1 and E-selectin expression. Eur. J. Immunol. 26, 120-129 (1996).
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 120-129
-
-
Zhou, L.1
Pope, B.L.2
Chourmouzis, E.3
Fung-Leung, W.-P.4
Lau, C.Y.5
-
26
-
-
0028090419
-
Tepoxalin, a novel immunosuppressive agent with a different mechanism of action from cyclosporin A
-
ZHOU, L, D. M. RITCHIE, E. Y. WANG, A. G. BARBONE, D. ARGENTIERI und C. Y. LAU. Tepoxalin, a novel immunosuppressive agent with a different mechanism of action from cyclosporin A. J. Immunol.: 5026-5037 (1994).
-
(1994)
J. Immunol.
, pp. 5026-5037
-
-
Zhou, L.1
Ritchie, D.M.2
Wang, E.Y.3
Barbone, A.G.4
Argentieri, D.5
Lau, C.Y.6
|