Mutation Induction by Heavy Ion Beams and X-rays: Analysis with cultured cell line

Nippon Acta Radiologica

Volumn 56, Issue 11, 1996, Pages 736-740

  Toya, Kazuhito ^a   Shigematsu, Naoyuki ^a   Ito, Hisao ^a   Yamashita, Shoji ^a   Kubo, Atsushi ^a   Kanai, Tatsuaki ^b  

^a KEIO UNIVERSITY   (Japan)

^b NATIONAL INSTRUMENTS   (United States)

Author keywords

Cultured cells; Heavy particles; Mutation; Relative biological effectiveness

Indexed keywords

CARBON; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; NEON;

ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CRICETULUS; DOSE RESPONSE; GENETICS; HAMSTER; MUTATION; RADIATION EXPOSURE; X RAY;

ANIMALS; CARBON; CELL SURVIVAL; CELLS, CULTURED; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTATION; NEON; X-RAYS;

EID: 0030227133     PISSN: 00480428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Barendsen GW, Walter HMD: Effect of different ionizing radiations on human cells in tissue culture. IV. Modification of radiation damage. Radiat Res 21: 314-329, 1964
2. 60Co γ -rays: evidence of repair of damage at reduced dose rate. Int J Radiat Biol 37: 585-589, 1980
3. Hill CK, Carnes BA, Han A, et al: Neoplastic transformation is enhanced by multiple low doses of fission-spectrum neutrons. Radiat Res 102. 404-410, 1985
4. Han A, Elkind MM: Transformation of mouse C3H/10T1/2 cells by single and fractionated doses of X-rays and fission-spectrum neutrons. Cancer Res 39: 123-130, 1979
5. Grdina DJ, Nagy B, Sigdestad CP: Radioprotectors in treatment therapy to reduce risk in secondary tumor induction. Pharmacol Ther 39: 21-25, 1988
6. Grdina DJ, Sigdestad CP: Radiation protectors: the unexpected benefits. Drug Metabolism Rev 20(1): 13-42, 1989
7. Holm LE: Cancer occurring after radiotherapy and chemotherapy. Int J Radiat Oncol Biol Phys 19: 1303-1308, 1990
8. Hawkins MM: Second primary tumors following radiotherapy for childhood cancer. Int J Radiat Oncol Biol Phys 19: 1297-1301, 1990
9. Ohara H, Kanai T, Ando K, et al: Studies on physics and biology of carbon beams of Riken and NIRS. Proceedings of the NIRS International Workshop on Heavy Charged Particle Therapy and Related Subjects. July 4-5, 1991, Chiba, Japan, p. 13-22
10. Li AP, Carver JH, Choy WN, et al: A guide for the performance of the chinese hamster ovary cell/hypoxanthine-guanine phosphoribosyl transferase gene mutation assay. Mutation Res 189: 135-141, 1987
11. Hsie AW, Casciano DA, Couch DB, et al: The use of chinese hamster ovary cells to quantify specific locus mutation and to determine mutagenicity of chemicals. Mutation Res 86: 193-214, 1981
12. Griffin TW, Wambersie A, Laramore G, et al: High LET: Heavy particle trials. Int J Radiat Oncol Biol Phys 14: 583-592, 1988
13. Castro JR, Quivey JM, Lyman JT, et al: Current status of clinical particle radiotherapy at Lawrence Berkeley Laboratory. Cancer 46: 633-641, 1980
14. Deering RA, Rice R: Heavy ion irradiation of Hela cells. Radiat Res 17: 774-786, 1962
15. Cox R, Masson WK: Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions: III human diploid fibroblasts. Int J Radiat Biol 36: 149-160, 1979
16. Kiefer J: Biological radiation effects. 1990, Springer-Verlag, Berlin. Heidelberg
17. Grdina DJ, Sigdestad CP, Carnes BA: Protection by WR1065 and WR151326 against fission-neutron-induced mutations at the HGPRT locus in V79 cells. Radiat Res 117: 500-510, 1989
18. Konig and J Kiefer: Lack of dose-rate effect for mutation induction by γ-rays in human TK6 cells. Int J Radiat Biol 54. 891-897, 1988