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Volumn 43, Issue 1, 2004, Pages 106-112

Role of Endothelin-1 and Thromboxane A2 in the Pulmonary Hypertension Induced by Heparin-Protamine Interaction in Anesthetized Dogs

Author keywords

Dazoxiben; Endothelin 1; Inhaled nitric oxide; Protamine; Pulmonary hypertension; Tezosentan

Indexed keywords

DAZOXIBEN; ENDOTHELIN 1; HEPARIN; INDOMETACIN; PROTAMINE; TEZOSENTAN; THROMBOXANE A2;

EID: 0346333124     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200401000-00016     Document Type: Article
Times cited : (11)

References (50)
  • 1
    • 0035676884 scopus 로고    scopus 로고
    • Pulmonary vascular remodeling: A target for therapeutic intervention in pulmonary hypertension
    • Jeffery TK, Wanstall JC. Pulmonary vascular remodeling: a target for therapeutic intervention in pulmonary hypertension. Pharmacol Ther. 2001;92:1-20.
    • (2001) Pharmacol Ther , vol.92 , pp. 1-20
    • Jeffery, T.K.1    Wanstall, J.C.2
  • 2
    • 0021022005 scopus 로고
    • Catastrophic pulmonary vasoconstriction associated with protamine reversal of heparin
    • Lowenstein E, Johnston WE, Lappas DG, et al. Catastrophic pulmonary vasoconstriction associated with protamine reversal of heparin. Anesthesiology. 1983;59:470-473.
    • (1983) Anesthesiology , vol.59 , pp. 470-473
    • Lowenstein, E.1    Johnston, W.E.2    Lappas, D.G.3
  • 3
    • 0023552586 scopus 로고
    • Hemodynamics of protamine administration. Comparison of right atrial, left atrial, and aortic injections
    • Katz NM, Kim YD, Siegelman R, et al. Hemodynamics of protamine administration. Comparison of right atrial, left atrial, and aortic injections. J Thorac Cardiovasc Surg. 1987;94:881-886.
    • (1987) J Thorac Cardiovasc Surg , vol.94 , pp. 881-886
    • Katz, N.M.1    Kim, Y.D.2    Siegelman, R.3
  • 4
    • 0025175070 scopus 로고
    • Thromboxane receptor blockade prevents pulmonary hypertension induced by heparin-protamine reactions in awake sheep
    • Montalescot G, Lowenstein E. Ogletree ML, et al. Thromboxane receptor blockade prevents pulmonary hypertension induced by heparin-protamine reactions in awake sheep. Circulation. 1990;82:1765-1777.
    • (1990) Circulation , vol.82 , pp. 1765-1777
    • Montalescot, G.1    Lowenstein, E.2    Ogletree, M.L.3
  • 5
  • 6
    • 0026751075 scopus 로고
    • Endothelial dysfunction in pulmonary hypertension
    • Loscalzo J. Endothelial dysfunction in pulmonary hypertension. N Engl J Med. 1992;327:117-119.
    • (1992) N Engl J Med , vol.327 , pp. 117-119
    • Loscalzo, J.1
  • 7
    • 0026544193 scopus 로고
    • Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure
    • Cody RJ, Haas GJ, Binkley PF, et al. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-509.
    • (1992) Circulation , vol.85 , pp. 504-509
    • Cody, R.J.1    Haas, G.J.2    Binkley, P.F.3
  • 8
    • 0028245569 scopus 로고
    • Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure
    • Tsutalnoto T, Wada AL, Maeda Y, et al. Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure. J Am Coll Cardiol. 1994;23:1427-1433.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1427-1433
    • Tsutalnoto, T.1    Wada, A.L.2    Maeda, Y.3
  • 9
    • 0036189492 scopus 로고    scopus 로고
    • Pulmonary hypertension secondary to left ventricular dysfunction: The role of nitric oxide and endothelin-1 in the control of pulmonary vascular tone
    • Deuchar GA, Docherty A, MacLean MR, et al. Pulmonary hypertension secondary to left ventricular dysfunction: the role of nitric oxide and endothelin-1 in the control of pulmonary vascular tone. Br J Pharmacol. 2002;135:1060-1068.
    • (2002) Br J Pharmacol , vol.135 , pp. 1060-1068
    • Deuchar, G.A.1    Docherty, A.2    MacLean, M.R.3
  • 10
    • 0036092602 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxido
    • Earley S, Nelin LD, Chicoine LG, et al. Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxido. J Appl Physiol. 2002;92:1152-1158.
    • (2002) J Appl Physiol , vol.92 , pp. 1152-1158
    • Earley, S.1    Nelin, L.D.2    Chicoine, L.G.3
  • 11
    • 0027052235 scopus 로고
    • Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells
    • Janakidevi K, Fisher MA, Del Vecchio PJ, et al. Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells. Am J Physiol. 1992;263:C1295-C1301.
    • (1992) Am J Physiol , vol.263
    • Janakidevi, K.1    Fisher, M.A.2    Del Vecchio, P.J.3
  • 12
    • 0020656612 scopus 로고
    • Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep
    • McDonald JW, Ali M, Morgan E, et al. Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. Circ Res. 1983;52:1-6.
    • (1983) Circ Res , vol.52 , pp. 1-6
    • McDonald, J.W.1    Ali, M.2    Morgan, E.3
  • 13
    • 0023884860 scopus 로고
    • Acute pulmonary vasoconstriction and thromboxane release during protamine reversal of heparin anticoagulation in awake sheep. Evidence for the role of reactive oxygen metabolites following non-immunological complement activation
    • Morel DR, Lowenstein E, Nguyenduy T, et al. Acute pulmonary vasoconstriction and thromboxane release during protamine reversal of heparin anticoagulation in awake sheep. Evidence for the role of reactive oxygen metabolites following non-immunological complement activation. Circ Res. 1988;62:905-915.
    • (1988) Circ Res , vol.62 , pp. 905-915
    • Morel, D.R.1    Lowenstein, E.2    Nguyenduy, T.3
  • 14
    • 0025871780 scopus 로고
    • Complications caused by protamine. 2. Therapy and prevention
    • Hobbhahn J, Habazettl H, Conzen P, et al. Complications caused by protamine. 2. Therapy and prevention. Anaesthesist. 1991;40:421-428.
    • (1991) Anaesthesist , vol.40 , pp. 421-428
    • Hobbhahn, J.1    Habazettl, H.2    Conzen, P.3
  • 15
    • 0023123320 scopus 로고
    • Sequestration of platelets in the pulmonary circulation as a consequence of protamine reversal of the anticoagulant effects of heparin
    • Wakefield TW, Bouffard JA, Spaulding SA, et al. Sequestration of platelets in the pulmonary circulation as a consequence of protamine reversal of the anticoagulant effects of heparin. J Vase Surg. 1987;5:187-193.
    • (1987) J Vase Surg , vol.5 , pp. 187-193
    • Wakefield, T.W.1    Bouffard, J.A.2    Spaulding, S.A.3
  • 16
    • 0031278058 scopus 로고    scopus 로고
    • Involvement of fibrinogen in protamine-induced pulmonary hypertension
    • Sogawa M, Mohammad SF. Involvement of fibrinogen in protamine-induced pulmonary hypertension. J Surg Rev. 1997;73:80-84.
    • (1997) J Surg Rev , vol.73 , pp. 80-84
    • Sogawa, M.1    Mohammad, S.F.2
  • 17
    • 0023262178 scopus 로고
    • C5a and thromboxane generation associated with pulmonary vaso- and bronchoconstriction during protamine reversal of heparin
    • Morel DR, Zapol WM, Thomas SJ, et al. C5a and thromboxane generation associated with pulmonary vaso- and bronchoconstriction during protamine reversal of heparin. Anesthesiology. 1987;66:597-604.
    • (1987) Anesthesiology , vol.66 , pp. 597-604
    • Morel, D.R.1    Zapol, W.M.2    Thomas, S.J.3
  • 18
    • 0024598118 scopus 로고
    • Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine
    • Weiss ME, Nyhan D, Peng ZK, et al. Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine. N Engl J Med. 1989;320:886-892.
    • (1989) N Engl J Med , vol.320 , pp. 886-892
    • Weiss, M.E.1    Nyhan, D.2    Peng, Z.K.3
  • 19
    • 0026002659 scopus 로고
    • Inhaled nitric oxide as a cause of selective pulmonary vasodilation in pulmonary hypertension
    • Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, et al. Inhaled nitric oxide as a cause of selective pulmonary vasodilation in pulmonary hypertension. Lancet. 1991;;338:1173-1174.
    • (1991) Lancet , vol.338 , pp. 1173-1174
    • Pepke-Zaba, J.1    Higenbottam, T.W.2    Dinh-Xuan, A.T.3
  • 20
    • 0025910315 scopus 로고
    • Inhaled nitric oxide: A selectively pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction
    • Frostell CG, Fratacci MD, Wain JCG, et al. Inhaled nitric oxide: A selectively pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation. 1991;83:2038-2047.
    • (1991) Circulation , vol.83 , pp. 2038-2047
    • Frostell, C.G.1    Fratacci, M.D.2    Wain, J.C.G.3
  • 22
    • 0021949898 scopus 로고
    • Protamine: A review of its toxicity
    • Horrow JC. Protamine: a review of its toxicity. Anesth Analg. 1985;64:348-361.
    • (1985) Anesth Analg , vol.64 , pp. 348-361
    • Horrow, J.C.1
  • 23
    • 0021279863 scopus 로고
    • Toward a better understanding of the hemodynamic effects of protamine and heparin interaction
    • Stefaniszyn HJ, Novick RJ, Salerno TA. Toward a better understanding of the hemodynamic effects of protamine and heparin interaction. J Thorac Cardiovasc Surg. 1984;87:678-686.
    • (1984) J Thorac Cardiovasc Surg , vol.87 , pp. 678-686
    • Stefaniszyn, H.J.1    Novick, R.J.2    Salerno, T.A.3
  • 24
    • 0029094565 scopus 로고
    • Heparin-protamine complexes cause pulmonary hypertension in goats
    • Horiguchi T, Enzan K, Mitsuhata H, et al. Heparin-protamine complexes cause pulmonary hypertension in goats. Anesthesioly. 1995;83:786-791.
    • (1995) Anesthesioly , vol.83 , pp. 786-791
    • Horiguchi, T.1    Enzan, K.2    Mitsuhata, H.3
  • 25
    • 0027323950 scopus 로고
    • Imaging the ovine heparin-protamine interaction with I I I in-protamine
    • Montalescot G, Fischman AJ, Strauss HW, et al. Imaging the ovine heparin-protamine interaction with I I I In-protamine. Appl Psysiol. 1993;75:963-971.
    • (1993) Appl Psysiol , vol.75 , pp. 963-971
    • Montalescot, G.1    Fischman, A.J.2    Strauss, H.W.3
  • 27
    • 0024537085 scopus 로고
    • Thromboxane mediation of pulmonary hemodynamic responses after neutralization of heparin by protamine in pigs
    • Conzen PF, Habazettl H, Gutmann R, et al. Thromboxane mediation of pulmonary hemodynamic responses after neutralization of heparin by protamine in pigs. Anesth Analg. 1989;68:25-31.
    • (1989) Anesth Analg , vol.68 , pp. 25-31
    • Conzen, P.F.1    Habazettl, H.2    Gutmann, R.3
  • 28
    • 0025652848 scopus 로고
    • Pulmonary hypertension after heparin-protamine: Roles of left-sided infusion, histamine, and platelet-activating factor
    • Habazettl H, Conzen PF, Vollmar B, et al. Pulmonary hypertension after heparin-protamine: roles of left-sided infusion, histamine, and platelet-activating factor. Anesth Analg. 1990;71:637-644.
    • (1990) Anesth Analg , vol.71 , pp. 637-644
    • Habazettl, H.1    Conzen, P.F.2    Vollmar, B.3
  • 29
    • 0025853273 scopus 로고
    • Protamine-heparin-induced pulmonary hypertension in pigs: Effects of treatment with a thromboxane receptor antagonist on hemodynamics and coagulation
    • Nuttall GA, Murray MJ, Walter-Bowie EJ. Protamine-heparin-induced pulmonary hypertension in pigs: effects of treatment with a thromboxane receptor antagonist on hemodynamics and coagulation. Anesthesiology. 1991;74:138-145.
    • (1991) Anesthesiology , vol.74 , pp. 138-145
    • Nuttall, G.A.1    Murray, M.J.2    Walter-Bowie, E.J.3
  • 30
    • 0033663781 scopus 로고    scopus 로고
    • Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-046) on protamine-induced circulatory changes in dogs
    • Mizutani T, Takahashi S, Kihara S, et al. Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-046) on protamine-induced circulatory changes in dogs. J Cardiothorac Vase Anesth. 2000;14:687-692.
    • (2000) J Cardiothorac Vase Anesth , vol.14 , pp. 687-692
    • Mizutani, T.1    Takahashi, S.2    Kihara, S.3
  • 31
    • 0032056061 scopus 로고    scopus 로고
    • Endothelin-1: A mediator of pulmonary hypertension?
    • MacLean RM. Endothelin-1: a mediator of pulmonary hypertension? Pulmon Pharmacol Therap. 1998;11:132.
    • (1998) Pulmon Pharmacol Therap , vol.11 , pp. 132
    • MacLean, R.M.1
  • 32
    • 0025892889 scopus 로고
    • Increased plasmaendothelin-1 in the early hours of acute myocardial infarction
    • Stewart DJ, Kubac G, Costello KB, et al. Increased plasmaendothelin-1 in the early hours of acute myocardial infarction. J Am Coll Cardiol. 1991;18:38-43.
    • (1991) J Am Coll Cardiol , vol.18 , pp. 38-43
    • Stewart, D.J.1    Kubac, G.2    Costello, K.B.3
  • 33
    • 0025838213 scopus 로고
    • Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation
    • Yoshibayashi M, Nishioka K, Nakao K, et al. Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation. Circulation. 1991;84:2280-2285.
    • (1991) Circulation , vol.84 , pp. 2280-2285
    • Yoshibayashi, M.1    Nishioka, K.2    Nakao, K.3
  • 34
    • 0034993096 scopus 로고    scopus 로고
    • Role of endothelin-1 in hypertension and vascular disease
    • Schiffrin EL. Role of endothelin-1 in hypertension and vascular disease. Am J Hypertens. 2001;14:833S-89S.
    • (2001) Am J Hypertens , vol.14
    • Schiffrin, E.L.1
  • 35
    • 0032766706 scopus 로고    scopus 로고
    • Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use
    • Clozel M, Ramuz H, Clozel JP, et al. Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use. J Pharmacol Exp Ther. 1999;290:840-846.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 840-846
    • Clozel, M.1    Ramuz, H.2    Clozel, J.P.3
  • 36
    • 0028844533 scopus 로고
    • A-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat
    • A-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat. Am J Physiol. 1995;269:L690-L697.
    • (1995) Am J Physiol , vol.269
    • Di Carlo, V.S.1    Chen, S.J.2    Meng, Q.C.3
  • 37
    • 0036070756 scopus 로고    scopus 로고
    • The endothelin A receptor antagonists PD 156707 (CI-1020) and PD 180988 (CI-1034) reverse the hypoxic pulmonary vasoconstriction in the perinatal lamb
    • Coe Y, Haleen SJ, Welch KM, et al. The endothelin A receptor antagonists PD 156707 (CI-1020) and PD 180988 (CI-1034) reverse the hypoxic pulmonary vasoconstriction in the perinatal lamb. J Pharmacol Exp Ther. 2002;302:672-680.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 672-680
    • Coe, Y.1    Haleen, S.J.2    Welch, K.M.3
  • 38
    • 0033970424 scopus 로고    scopus 로고
    • The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs
    • Tanus-Santos JE, Gordo WM, Udelsmann A, et al. The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs. Anesth Analg. 2000;90:102-106.
    • (2000) Anesth Analg , vol.90 , pp. 102-106
    • Tanus-Santos, J.E.1    Gordo, W.M.2    Udelsmann, A.3
  • 39
    • 0035895324 scopus 로고    scopus 로고
    • A antagonist in rats with monocrotaline-induced pulmonary hypertension
    • A antagonist in rats with monocrotaline-induced pulmonary hypertension. Circulation. 2001;103:314-318.
    • (2001) Circulation , vol.103 , pp. 314-318
    • Jasmin, J.F.1    Lucas, M.2    Cemacek, P.3
  • 40
    • 0029781393 scopus 로고    scopus 로고
    • 2 increases the vasoconstrictor effect of endothelin-1 in postischemic reperfused rat hearts
    • 2 increases the vasoconstrictor effect of endothelin-1 in postischemic reperfused rat hearts. Circulation. 1996;94:742-747.
    • (1996) Circulation , vol.94 , pp. 742-747
    • Zaugg, C.E.1    Hornstein, P.S.2    Zhu, P.3
  • 41
    • 0025195343 scopus 로고
    • 2 receptor in the vasoconstrictor response of rat aorta to endothelin
    • 2 receptor in the vasoconstrictor response of rat aorta to endothelin. J Pharmacol Exp Ther. 1990;252:915-921.
    • (1990) J Pharmacol Exp Ther , vol.252 , pp. 915-921
    • Reynolds, E.E.1    Mok, L.L.2
  • 42
    • 0025641739 scopus 로고
    • Endothelin-1 and platelet activating factor stimulate thromboxane A2 biosynthesis in rat vascular smooth muscle cells
    • Takayasu-Okishio M, Terashita Z, et al. Endothelin-1 and platelet activating factor stimulate thromboxane A2 biosynthesis in rat vascular smooth muscle cells. Biochem Pharmacol. 1990;40:2713-2717.
    • (1990) Biochem Pharmacol , vol.40 , pp. 2713-2717
    • Takayasu-Okishio, M.1    Terashita, Z.2
  • 43
    • 0035216242 scopus 로고    scopus 로고
    • U-46619-induced potentiation of noradrenergic constriction in the human saphenous vein: Antagonism by thromboxane receptor blockade
    • Vila JM, Martinez-Leon JB, Medina P, et al. U-46619-induced potentiation of noradrenergic constriction in the human saphenous vein: antagonism by thromboxane receptor blockade. Cardiovasc Res. 2001;52:462-467.
    • (2001) Cardiovasc Res , vol.52 , pp. 462-467
    • Vila, J.M.1    Martinez-Leon, J.B.2    Medina, P.3
  • 45
    • 0034940315 scopus 로고    scopus 로고
    • Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension
    • Tilton RG, Brock TA, Dixon RA. Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension. Exp Opin Investig Drugs. 2001;10:1291-1308.
    • (2001) Exp Opin Investig Drugs , vol.10 , pp. 1291-1308
    • Tilton, R.G.1    Brock, T.A.2    Dixon, R.A.3
  • 46
    • 0034813319 scopus 로고    scopus 로고
    • Reciprocal regulation of endothelin-1 and nitric oxide: Relevance in the physiology and pathology of the cardiovascular system
    • Rossi GP, Seccia TM, Nussdorfer GG. Reciprocal regulation of endothelin-1 and nitric oxide: relevance in the physiology and pathology of the cardiovascular system. Inv Rev Cytol. 2001;209:241-272.
    • (2001) Inv Rev Cytol , vol.209 , pp. 241-272
    • Rossi, G.P.1    Seccia, T.M.2    Nussdorfer, G.G.3
  • 48
    • 0030031216 scopus 로고    scopus 로고
    • Increased release of NO during ischemia reduces myocardial contractility and improves metabolic dysfunction
    • Node K, Kitakaze M, Kosaka H, et al. Increased release of NO during ischemia reduces myocardial contractility and improves metabolic dysfunction. Circulation. 1996;93:356-364.
    • (1996) Circulation , vol.93 , pp. 356-364
    • Node, K.1    Kitakaze, M.2    Kosaka, H.3
  • 49
    • 0027053340 scopus 로고
    • Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia
    • Brady AJB, Poole-Wilson PA, Harding SE, et al. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol. 1992;263:H1963-H1966.
    • (1992) Am J Physiol , vol.263
    • Brady, A.J.B.1    Poole-Wilson, P.A.2    Harding, S.E.3
  • 50
    • 0032211702 scopus 로고    scopus 로고
    • 1: Effect on left ventricular contractility when used for treatment of experimental pulmonary hypertension
    • 1: effect on left ventricular contractility when used for treatment of experimental pulmonary hypertension. Eur J Cardiothorac Surg. 1998;14:494-502.
    • (1998) Eur J Cardiothorac Surg , vol.14 , pp. 494-502
    • Krieg, P.1    Wahlers, T.2    Giess, W.3


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