-
1
-
-
0021741006
-
Monosodium glutamate and analgesia induced by morphine, test-specific effects
-
Badillo-Martinez D., Kirchgessner A.L., Butler P.D., Bodnar R.J. Monosodium glutamate and analgesia induced by morphine, test-specific effects. Neuropharmacology. 23:1984;1141-1149.
-
(1984)
Neuropharmacology
, vol.23
, pp. 1141-1149
-
-
Badillo-Martinez, D.1
Kirchgessner, A.L.2
Butler, P.D.3
Bodnar, R.J.4
-
2
-
-
0027992360
-
Diversity of agents that modify opioid tolerance, physical dependence, abstinence syndrome, and self-administrative behavior
-
Bhargava H.N. Diversity of agents that modify opioid tolerance, physical dependence, abstinence syndrome, and self-administrative behavior. Pharmacol. Rev. 46:1994;293-324.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 293-324
-
-
Bhargava, H.N.1
-
3
-
-
0031418037
-
5]enkephalin on the concentration of cGMP in brain regions and spinal cord of the mouse
-
5]enkephalin on the concentration of cGMP in brain regions and spinal cord of the mouse. Peptides. 18:1997;1629-1634.
-
(1997)
Peptides
, vol.18
, pp. 1629-1634
-
-
Bhargava, H.N.1
Cao, Y.J.2
-
4
-
-
0024510439
-
Effect of morphine in rats treated chronically with U-50,488H, a κ opioid receptor agonist
-
Bhargava H.N., Ramarao P., Gulati A. Effect of morphine in rats treated chronically with U-50,488H, a κ opioid receptor agonist. Eur. J. Pharmacol. 162:1989;257-264.
-
(1989)
Eur. J. Pharmacol.
, vol.162
, pp. 257-264
-
-
Bhargava, H.N.1
Ramarao, P.2
Gulati, A.3
-
5
-
-
0028278085
-
Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist, in the mouse
-
Bhargava H.N., Thorat S.N. Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist, in the mouse. Brain Res. 649:1994;111-116.
-
(1994)
Brain Res.
, vol.649
, pp. 111-116
-
-
Bhargava, H.N.1
Thorat, S.N.2
-
6
-
-
0024430453
-
Effect of chronic administration of U-50,488H, on tolerance to its pharmacological actions and multiple opioid receptors in rat brain regions and spinal cord
-
Bhargava H.N., Gulati A., Ramarao P. Effect of chronic administration of U-50,488H, on tolerance to its pharmacological actions and multiple opioid receptors in rat brain regions and spinal cord. J. Pharmacol. Exp. Ther. 251:1989;21-26.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 21-26
-
-
Bhargava, H.N.1
Gulati, A.2
Ramarao, P.3
-
7
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
8
-
-
0023737135
-
A novel series of potent and selective agonists at the opioid κ-receptor
-
Costello G.F., Main B.G., Barlow J.J., Carroll J.A., Shaw J.S. A novel series of potent and selective agonists at the opioid κ-receptor. Eur. J. Pharmacol. 151:1988;475-478.
-
(1988)
Eur. J. Pharmacol.
, vol.151
, pp. 475-478
-
-
Costello, G.F.1
Main, B.G.2
Barlow, J.J.3
Carroll, J.A.4
Shaw, J.S.5
-
9
-
-
0025022204
-
Effect of nor-binaltorphimine on the behavior of mice and rats receiving multiple injections of U-50,488
-
Cowan A., Murray C.W. Effect of nor-binaltorphimine on the behavior of mice and rats receiving multiple injections of U-50,488. Prog. Clin. Biol. Res. 328:1990;303-306.
-
(1990)
Prog. Clin. Biol. Res.
, vol.328
, pp. 303-306
-
-
Cowan, A.1
Murray, C.W.2
-
10
-
-
0023836656
-
Opposite effects of μ and κ opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats
-
Di Chiara G., Imperato A. Opposite effects of μ and κ opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J. Pharmacol. Exp. Ther. 244:1988;1067-1080.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 1067-1080
-
-
Di Chiara, G.1
Imperato, A.2
-
11
-
-
0033543752
-
Potent antinociceptive effects of TRK-820, a novel κ-opioid receptor agonist
-
Endoh T., Matsuura H., Tajima A., Izumimoto N., Tajima C., Suzuki T., Saitoh A., Suzuki T., Narita M., Tseng L., Nagase H. Potent antinociceptive effects of TRK-820, a novel κ-opioid receptor agonist. Life Sci. 65:1999;1685-1694.
-
(1999)
Life Sci.
, vol.65
, pp. 1685-1694
-
-
Endoh, T.1
Matsuura, H.2
Tajima, A.3
Izumimoto, N.4
Tajima, C.5
Suzuki, T.6
Saitoh, A.7
Suzuki, T.8
Narita, M.9
Tseng, L.10
Nagase, H.11
-
12
-
-
0033955540
-
Characterization of the antinociceptive effects of TRK-820 in the rat
-
Endoh T., Tajima A., Kamei J., Suzuki T., Narita M., Tseng L., Nagase H. Characterization of the antinociceptive effects of TRK-820 in the rat. Eur. J. Pharmacol. 387:2000;133-140.
-
(2000)
Eur. J. Pharmacol.
, vol.387
, pp. 133-140
-
-
Endoh, T.1
Tajima, A.2
Kamei, J.3
Suzuki, T.4
Narita, M.5
Tseng, L.6
Nagase, H.7
-
13
-
-
0035071844
-
TRK-820, a selective κ-opioid agonist, produces potent antinociception in cynomolgus monkeys
-
Endoh T., Tajima A., Izumimoto N., Suzuki T., Saitoh A., Suzuki T., Narita M., Kamei J., Tseng L.F., Mizoguchi H., Nagase H. TRK-820, a selective κ-opioid agonist, produces potent antinociception in cynomolgus monkeys. Jpn. J. Pharmacol. 85:2001;282-290.
-
(2001)
Jpn. J. Pharmacol.
, vol.85
, pp. 282-290
-
-
Endoh, T.1
Tajima, A.2
Izumimoto, N.3
Suzuki, T.4
Saitoh, A.5
Suzuki, T.6
Narita, M.7
Kamei, J.8
Tseng, L.F.9
Mizoguchi, H.10
Nagase, H.11
-
14
-
-
0028555868
-
Enhancement of the rate of GTP hydrolysis in rat brain by repeated κ-opioid treatment
-
Feng Y., Narita M., Makimura M., Hoskins B., Ho I.K. Enhancement of the rate of GTP hydrolysis in rat brain by repeated κ-opioid treatment. Brain Res. 667:1994;133-137.
-
(1994)
Brain Res.
, vol.667
, pp. 133-137
-
-
Feng, Y.1
Narita, M.2
Makimura, M.3
Hoskins, B.4
Ho, I.K.5
-
16
-
-
84916016226
-
Statistical Methods in Biological Assays
-
New York: Hafner Publishing
-
Finney D.J. Statistical Methods in Biological Assays. 2nd ed. 1964;Hafner Publishing, New York.
-
(1964)
2nd Ed.
-
-
Finney, D.J.1
-
17
-
-
0028142488
-
Pharmacological properties of R-84760, a novel κ-opioid receptor agonist
-
Fujibayashi K., Sakamoto K., Watanabe M., Iizuka Y. Pharmacological properties of R-84760, a novel κ-opioid receptor agonist. Eur. J. Pharmacol. 261:1994;133-140.
-
(1994)
Eur. J. Pharmacol.
, vol.261
, pp. 133-140
-
-
Fujibayashi, K.1
Sakamoto, K.2
Watanabe, M.3
Iizuka, Y.4
-
18
-
-
0037169345
-
Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization
-
He L., Fong J., von Zastrow M., Whistler J.L. Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. Cell. 108:2002;271-282.
-
(2002)
Cell
, vol.108
, pp. 271-282
-
-
He, L.1
Fong, J.2
Von Zastrow, M.3
Whistler, J.L.4
-
19
-
-
0024472932
-
Serotonergic involvement in the antinociceptive action of and the development of tolerance to the kappa-opioid receptor agonist, U-50,488H
-
Ho B.Y., Takemori A.E. Serotonergic involvement in the antinociceptive action of and the development of tolerance to the kappa-opioid receptor agonist, U-50,488H. J. Pharmacol. Exp. Ther. 250:1989;508-514.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.250
, pp. 508-514
-
-
Ho, B.Y.1
Takemori, A.E.2
-
20
-
-
0029033163
-
Preventing morphine antinociceptive tolerance by irreversible mu opioid antagonists before the onset of their antagonism
-
Jiang Q., Seyed-Mozaffari A., Sebastian A., Archer S., Bidlack J.M. Preventing morphine antinociceptive tolerance by irreversible mu opioid antagonists before the onset of their antagonism. J. Pharmacol. Exp. Ther. 273:1995;680-688.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.273
, pp. 680-688
-
-
Jiang, Q.1
Seyed-Mozaffari, A.2
Sebastian, A.3
Archer, S.4
Bidlack, J.M.5
-
21
-
-
0035895840
-
Morphine tolerance after chronic intracerebroventricular injection in male and female mice
-
Kest B., Hopkins E. Morphine tolerance after chronic intracerebroventricular injection in male and female mice. Brain Res. 892:2001;208-210.
-
(2001)
Brain Res.
, vol.892
, pp. 208-210
-
-
Kest, B.1
Hopkins, E.2
-
22
-
-
0034613234
-
A comparison of morphine analgesic tolerance in male and female mice
-
Kest B., Palmese C., Hopkins E. A comparison of morphine analgesic tolerance in male and female mice. Brain Res. 879:2000;17-22.
-
(2000)
Brain Res.
, vol.879
, pp. 17-22
-
-
Kest, B.1
Palmese, C.2
Hopkins, E.3
-
23
-
-
0024444234
-
Analgesic activity of spiradoline mesylate (U-62,066E), a κ opioid agonist in mice
-
Kunihara M., Ohyama M., Nakano M., Hayashi S. Analgesic activity of spiradoline mesylate (U-62,066E), a κ opioid agonist in mice. Life Sci. 45:1989;1191-1198.
-
(1989)
Life Sci.
, vol.45
, pp. 1191-1198
-
-
Kunihara, M.1
Ohyama, M.2
Nakano, M.3
Hayashi, S.4
-
24
-
-
0033597143
-
U50,488H-induced internalization of the human κ opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. κ Receptor internalization is not required for mitogen-activated protein kinase activation
-
Li J.G., Luo L.Y., Krupnick J.G., Benovic J.L., Liu-Chen L.Y. U50,488H-induced internalization of the human κ opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. κ Receptor internalization is not required for mitogen-activated protein kinase activation. J. Biol. Chem. 274:1999;12087-12094.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12087-12094
-
-
Li, J.G.1
Luo, L.Y.2
Krupnick, J.G.3
Benovic, J.L.4
Liu-Chen, L.Y.5
-
25
-
-
0033798515
-
Mechanisms of agonist-induced down-regulation of the human κ-opioid receptor: Internalization is required for down-regulation
-
Li J.G., Benovic J.L., Liu-Chen L.Y. Mechanisms of agonist-induced down-regulation of the human κ-opioid receptor: internalization is required for down-regulation. Mol. Pharmacol. 58:2000;795-801.
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 795-801
-
-
Li, J.G.1
Benovic, J.L.2
Liu-Chen, L.Y.3
-
26
-
-
0037405881
-
Differential regulation of the human κ opioid receptor by agonists: Etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation
-
Li J.G., Zhang F., Jin X.L., Liu-Chen L.Y. Differential regulation of the human κ opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation. J. Pharmacol. Exp. Ther. 305:2003;531-540.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 531-540
-
-
Li, J.G.1
Zhang, F.2
Jin, X.L.3
Liu-Chen, L.Y.4
-
27
-
-
0024325328
-
Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model
-
Ling G.S., Paul D., Simantov R., Pasternak G.W. Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model. Life Sci. 45:1989;1627-1636.
-
(1989)
Life Sci.
, vol.45
, pp. 1627-1636
-
-
Ling, G.S.1
Paul, D.2
Simantov, R.3
Pasternak, G.W.4
-
29
-
-
0021049819
-
Pharmacology of opioids
-
Martin W.R. Pharmacology of opioids. Pharmacol. Rev. 35:1983;283-323.
-
(1983)
Pharmacol. Rev.
, vol.35
, pp. 283-323
-
-
Martin, W.R.1
-
30
-
-
0025141368
-
κ-Opioid receptors and analgesia
-
Millan M.J. κ-Opioid receptors and analgesia. Trends Pharmacol. Sci. 11:1990;70-76.
-
(1990)
Trends Pharmacol. Sci.
, vol.11
, pp. 70-76
-
-
Millan, M.J.1
-
31
-
-
0023946921
-
Interaction of RO 15-4513 and ethanol on the behaviour of mice: Antagonistic or additive effects?
-
Misslin R., Belzung C., Vogel E. Interaction of RO 15-4513 and ethanol on the behaviour of mice: antagonistic or additive effects? Psychopharmacology (Berl.). 94:1988;392-396.
-
(1988)
Psychopharmacology (Berl.)
, vol.94
, pp. 392-396
-
-
Misslin, R.1
Belzung, C.2
Vogel, E.3
-
32
-
-
0018356546
-
Quantitative relationships among measures of morphine tolerance and physical dependence in the rat
-
Mucha R.F., Kalant H., Linseman M.A. Quantitative relationships among measures of morphine tolerance and physical dependence in the rat. Pharmacol. Biochem. Behav. 10:1979;397-405.
-
(1979)
Pharmacol. Biochem. Behav.
, vol.10
, pp. 397-405
-
-
Mucha, R.F.1
Kalant, H.2
Linseman, M.A.3
-
33
-
-
0031915119
-
Discovery of a structurally novel opioid κ-agonist derived from 4,5-epoxymorphinan
-
Nagase H., Hayakawa J., Kawamura K., Kawai K., Takezawa Y., Matsuura H., Tajima C., Endo T. Discovery of a structurally novel opioid κ-agonist derived from 4,5-epoxymorphinan. Chem. Pharm. Bull. (Tokyo). 46:1998;366-369.
-
(1998)
Chem. Pharm. Bull. (Tokyo)
, vol.46
, pp. 366-369
-
-
Nagase, H.1
Hayakawa, J.2
Kawamura, K.3
Kawai, K.4
Takezawa, Y.5
Matsuura, H.6
Tajima, C.7
Endo, T.8
-
34
-
-
0028364324
-
Influence of chronic morphine treatment on protein kinase C activity: Comparison with butorphanol and implication for opioid tolerance
-
Narita M., Makimura M., Feng Y., Hoskins B., Ho I.K. Influence of chronic morphine treatment on protein kinase C activity: comparison with butorphanol and implication for opioid tolerance. Brain Res. 650:1994;175-179.
-
(1994)
Brain Res.
, vol.650
, pp. 175-179
-
-
Narita, M.1
Makimura, M.2
Feng, Y.3
Hoskins, B.4
Ho, I.K.5
-
35
-
-
0027173626
-
Cellular responses to chronic treatment with drugs of abuse
-
Nestler E.J. Cellular responses to chronic treatment with drugs of abuse. Crit. Rev. Neurobiol. 7:1993;23-39.
-
(1993)
Crit. Rev. Neurobiol.
, vol.7
, pp. 23-39
-
-
Nestler, E.J.1
-
36
-
-
0036892880
-
Opioid agonists differentially regulate μ-opioid receptors and trafficking proteins in vivo
-
Patel M.B., Patel C.N., Rajashekara V., Yoburn B.C. Opioid agonists differentially regulate μ-opioid receptors and trafficking proteins in vivo. Mol. Pharmacol. 62:2002;1464-1470.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1464-1470
-
-
Patel, M.B.1
Patel, C.N.2
Rajashekara, V.3
Yoburn, B.C.4
-
37
-
-
0020404219
-
U-50488H, a pure kappa receptor agonist with spinal analgesic loci in the mouse
-
Piercey M.F., Lahti R.A., Schroeder L.A., Einspahr F.J., Barsuhn C. U-50488H, a pure kappa receptor agonist with spinal analgesic loci in the mouse. Life Sci. 31:1982;1197-1200.
-
(1982)
Life Sci.
, vol.31
, pp. 1197-1200
-
-
Piercey, M.F.1
Lahti, R.A.2
Schroeder, L.A.3
Einspahr, F.J.4
Barsuhn, C.5
-
38
-
-
0032987630
-
Pharmacological properties of TRK-820 on cloned μ-, δ- And κ-opioid receptors and nociceptin receptor
-
Seki T., Awamura S., Kimura C., Ide S., Sakano K., Minami M., Nagase H., Satoh M. Pharmacological properties of TRK-820 on cloned μ-, δ- and κ-opioid receptors and nociceptin receptor. Eur. J. Pharmacol. 376:1999;159-167.
-
(1999)
Eur. J. Pharmacol.
, vol.376
, pp. 159-167
-
-
Seki, T.1
Awamura, S.2
Kimura, C.3
Ide, S.4
Sakano, K.5
Minami, M.6
Nagase, H.7
Satoh, M.8
-
39
-
-
0030201007
-
The stimulatory effects of opioids and their possible role in the development of tolerance
-
Smart D., Lambert D.G. The stimulatory effects of opioids and their possible role in the development of tolerance. Trends Pharmacol. Sci. 17:1996;264-269.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 264-269
-
-
Smart, D.1
Lambert, D.G.2
-
41
-
-
0027270774
-
Evidence for the role of nitric oxide in κ opiate tolerance in mice
-
Thorat S.N., Reddy P.L., Bhargava H.N. Evidence for the role of nitric oxide in κ opiate tolerance in mice. Brain Res. 621:1993;171-174.
-
(1993)
Brain Res.
, vol.621
, pp. 171-174
-
-
Thorat, S.N.1
Reddy, P.L.2
Bhargava, H.N.3
-
42
-
-
0037169176
-
Antipruritic activity of the κ-opioid receptor agonist, TRK-820
-
Togashi Y., Umeuchi H., Okano K., Ando N., Yoshizawa Y., Honda T., Kawamura K., Endoh T., Utsumi J., Kamei J., Tanaka T., Nagase H. Antipruritic activity of the κ-opioid receptor agonist, TRK-820. Eur. J. Pharmacol. 435:2002;259-264.
-
(2002)
Eur. J. Pharmacol.
, vol.435
, pp. 259-264
-
-
Togashi, Y.1
Umeuchi, H.2
Okano, K.3
Ando, N.4
Yoshizawa, Y.5
Honda, T.6
Kawamura, K.7
Endoh, T.8
Utsumi, J.9
Kamei, J.10
Tanaka, T.11
Nagase, H.12
-
43
-
-
0034616301
-
The novel κ-opioid receptor agonist TRK-820 has no affect on the development of antinociceptive tolerance to morphine in mice
-
Tsuji M., Yamazaki M., Takeda H., Matsumiya T., Nagase H., Tseng L.F., Narita M., Suzuki T. The novel κ-opioid receptor agonist TRK-820 has no affect on the development of antinociceptive tolerance to morphine in mice. Eur. J. Pharmacol. 394:2000;91-95.
-
(2000)
Eur. J. Pharmacol.
, vol.394
, pp. 91-95
-
-
Tsuji, M.1
Yamazaki, M.2
Takeda, H.3
Matsumiya, T.4
Nagase, H.5
Tseng, L.F.6
Narita, M.7
Suzuki, T.8
-
44
-
-
0035793821
-
The novel κ-opioid receptor agonist TRK-820 suppresses the rewarding and locomotor-enhancing effects of morphine in mice
-
Tsuji M., Takeda H., Matsumiya T., Nagase H., Narita M., Suzuki T. The novel κ-opioid receptor agonist TRK-820 suppresses the rewarding and locomotor-enhancing effects of morphine in mice. Life Sci. 68:2001;1717-1725.
-
(2001)
Life Sci.
, vol.68
, pp. 1717-1725
-
-
Tsuji, M.1
Takeda, H.2
Matsumiya, T.3
Nagase, H.4
Narita, M.5
Suzuki, T.6
-
46
-
-
0026562252
-
3H]-U69,593 binding sites in the rat heart
-
3H]-U69,593 binding sites in the rat heart. Life Sci. 50:1992;1143-1148.
-
(1992)
Life Sci.
, vol.50
, pp. 1143-1148
-
-
Xia, Q.1
Tai, K.K.2
Wong, T.M.3
-
47
-
-
0030915419
-
The development of morphine tolerance and dependence in rats with chronic pain
-
Yu W., Hao J.X., Xu X.J., Wiesenfeld-Hallin Z. The development of morphine tolerance and dependence in rats with chronic pain. Brain Res. 756:1997;141-146.
-
(1997)
Brain Res.
, vol.756
, pp. 141-146
-
-
Yu, W.1
Hao, J.X.2
Xu, X.J.3
Wiesenfeld-Hallin, Z.4
|