Cell Kinetic Study of Tamoxifen Treated MCF-7 and MDA-MB 468 Breast Cancer Cell Lines

Iranian Biomedical Journal

Volumn 7, Issue 2, 2003, Pages 51-56

  Karami Tehrani, Fatemeh ^a   Salami, Siamak ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Annexin V PI; Apoptosis; Breast cancer cell lines; Flow cytometry; Tamoxifen

Indexed keywords

TAMOXIFEN;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL DEATH; CELL KINETICS; CELL LINE MDA MB 468; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0346119203     PISSN: 1028852X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Tamm, I., Schriever, F. and Dorken, B. (2001) Apoptosis: implications of basic research for clinical oncology. Lancet Oncol. 2: 33-42.
2. Reed, J.C. (1999) Dysregulation of apoptosis in cancer. J. Clin. Oncol. 17: 2941-2953.
3. Mc. Pherson, K., Steel, C.M. and Dixon, J.M. (2000) ABC of the breast diseases, breast cancer epidemiology, risk factors and genetics. Br. Med. J. 321: 624-628.
4. Parton, M.; Dowsett, M. and Smith, I. (2001) Studies of apoptosis in breast cancer. Br. Med. J. 322: 1528-1532.
5. Wyld, D.K., Chester, J.D. and Perren, T.J. (1998) Endocrine aspect of the clinical management of the breast cancer-current issues. Endocr. Relat. Cancer 58: 97-110.
6. Wilson, A.J., Tehrani, F. and Baum, M. (1982) Adjuvant tamoxifen therapy for early breast cancer: an experimental study with reference to estrogen and progesterone receptor. Br. J. Surg. 69: 121-125.
7. Jordan, V.C. (1994) Molecular mechanisms of antiestrogen action in breast cancer. Breast Cancer Res. Treat. 31: 41-52.
8. Mandlekar, S. and Kong, A.N.T. (2001) Mechanisms of tamoxifen-induced apoptosis. Apoptosis 6: 469-477.
9. Frankfurt, O.S., Sugarbaker, E.V., Robb, J.A. and Villa, L. (1995) Synergistic induction of apoptosis in breast cancercells by tamoxifen and calmoduline inhibitors. Cancer Lett. 97: 149-154.
10. Maccarrone, M., Fantini, C., Ranalli, M., Melino, G. and Agro, A.F. (1998) Activation of nitric oxide synthase is involved in tamoxifen-induced apoptosis of human erythroleukemia K562 cells. FEBS Lett. 434: 421-424.
11. Darzynkiewicz, Z. and Traganos, F. (1998) Measurement of apoptosis. Advances in Biochemical Engineering/Biothecnology. 62: 33-73.
12. Hashimoto, M., Inoue, S., Muramatsu, M. and Masliah, E. (1997) Estrogens stimulate tamoxifen-induced neuronal cell apoptosis in Vitro: A possible nongenomic action. Biochem. Biophys. Res. Commun. 240: 464-470.
13. Ercoli, A., Scambia, G., Fattorossi, A., Raspaglio, G., Battaglia, A., Cicchillitti, L., Malorni, W., Rainaldi, G., Benedetti Panici, P. and Mancuso, S. (1998) Comparative study on the induction of cytostasis and apoptosis by ICI 182, 780 and tamoxifen in an estrogen receptor-negative ovarian cancer cell line. Int. J. Cancer 76: 47-54.
14. Ferlini, C., Scambia, G., Marone, M., Distefano, M., Gaggini, C., Ferrandina, G., Fattorossi, A., Isola, G., Benedetti Panici, P. and Mancuso, S. (1999) Tamoxifen induces oxidative stress and apoptosis in estrogen receptor-negative human cancer cell lines. Br. J. Cancer 79: 257-263.
15. Otto, A.M., Paddenberg, R., Schubert, S. and Maanherz, H.G. (1996) Cell-cycle arrest, micronucleus formation, and cell death in growth inhibition of MCF-7 breast cancer cells by tamoxifen and cisplatin. J. Cancer Res. Clin. Oncol. 122: 603-612.
16. Budtz, P.E. (1999) Role of proliferation and apoptosis in net growth rates of human breast cancer cells (MCF-7) treated with estradiol and/or tamoxifen. Cell Prolif. 32: 289-302.
17. Carthew, P., Nolan, B.M., Edwards, R.E. and Smith, L.L. (1996) The role of cell death and cell proliferation in the promotion of rat liver tumours by tamoxifen. Cancer Lett. 106: 163-169.
18. Robinson, E.K., Grau, A.M., Evans, D.B., Smid, C.M., Chiao, P.J., Abbruzzese, J.L. and Grimm, E.A. (1998). Cell cycle regulation of human pancreatic cancer by tamoxifen. Ann. Surg. Oncol. 5: 342-349.
19. Zhang, W., Couldwell, W.T., Song, H., Takano, T., Lin, J.H. and Nedergaard, M. (2000) Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells. Cancer Res. 60: 5395-5400.