Immunophenotyping by flow cytometry of peripheral blood lymphocytes from Chilean chronic chagasic patients;Inmunofenotipificación de linfocitos en sangre periférica de pacientes chagásicos crónicos chilenos mediante citometría de flujo

Revista Medica de Chile

Volumn 130, Issue 4, 2002, Pages 363-367

  Sánchez, Gittith ^a,b   Zulantay, Inés ^a   Gajardo, Marta ^a   Venegas, Juan ^a   Villanueva, Roxana ^a   Pérez, Andrés ^a   Liendo, Federico ^a   Apt, Werner ^a   Solari, Aldo ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b NONE   (Chile)

Author keywords

CD4 CD8 ratio; CD4 positive T lymphocytes; CD8 positive T lymphocytes; Chagas disease; Flow cytometry

Indexed keywords

ADULT; ARTICLE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHAGAS DISEASE; CHILE; CHRONIC DISEASE; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MALE; METHODOLOGY; MIDDLE AGED;

ADULT; CD4-CD8 RATIO; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHAGAS DISEASE; CHILE; CHRONIC DISEASE; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MALE; MIDDLE AGED;

EID: 0346046835     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. ANDRADE Z. Pathogenesis of Chagas' disease. Res Immunol 1991; 142: 126-9.
2. MACEDO AM, PENA SDJ. Genetic variability of Trypanosoma cruzi: Implications for the pathogenesis of Chagas' disease. Parasitology Today 1998; 14: 119-24.
3. APT W, AGUILERA X, ARRIBADA A, PÉREZ C, MIRANDA C, SÁNCHEZ G, ZULANTAY I, CORTÉS P, RODRÍGUEZ J, JURI D. Treatment of chronic Chagas disease with itraconazole and allopurinol. Am J Trop Med Hyg 1998; 59: 133-8.
4. TARLETON RL. The role of T cells in Trypanosoma cruzi infection. Parasitology Today 1995; 11: 7-9.
5. BRENER Z, GAZZINELLI RT. Immunological control Trypanosoma cruzi infection and pathogenesis of Chagas' disease. Internal Archiv Allergy Immunology 1997; 114: 103-10.
6. HIGUSHI MD, RIES MM, AIELLO VD, BENVENUTI LA, GUTIÉRREZ PS, BELLOTTI G, PILEGGI F. Association of an increase of CD8+ T cells with the presence of Trypanosoma cruzi antigens in chronic, human, chagasic myocarditis. Am J Trop Med Hyg 1997; 56: 485-9.
7. MIYAHIRA Y, KOBAYASHI S, TAKEUCHI T, KAMIYAMA T, NARA T, NAKAYIMA T, SHIMADA J, AOKI T. Induction of CD8+ T cell-mediated protective immunity against Trypanosoma cruzi. International Immunology 1999; 11: 133-41.
8. MINOPRIO P, ITOHARA S, HENSSER C, TONEGAWA S, COUTINHO A. Immunobiology of murine Trypanosoma cruzi infection: the predominance of parasitaemia non specific responses and the activation of TCR I T cells. Immunological Review 1989; 112: 183-205.
9. SZTEIN MB, KIERSZENBAUM F. Supression by Trypanosoma cruzi of T-cell receptor expression by activated human lymphocytes. Immunology 1992; 77: 277-83.
10. UNE C, ANDERSON J, ELORANTA ML, SUNNEMARK D, HARRIS RA, ORN A. Enhancement of natural killer (NK) cell cytotoxicity and induction of NK cell-derived interferon-gamma (IFN-γ) display different kinetics during experimental infection with Trypanosoma cruzi. Clin Exp Immunol 2000; 121: 499-505.
11. DUTRA WO, MARTINS-FILHO OA, CANÇADO JR, PINTO DIAS JC, BRENER Z, FREEMAN JUNIOR GL, COLLEY DG, GAZINELLI G, PARRA JC. Activated T and B lymphocytes in peripheral blood of patients with Chagas' disease. International Immunology 1994; 6: 499-506.
12. BRANDARIZ S. Detection of parasites DNA in Chagas hearth disease. Lancet 1996; 347: 914.
13. PRETY K, EISEN H. Chagas' disease: A model for the stydy of autoimmune diseases. Parasitology Today 1989; 5: 111-6.
14. BARNABE C, BRISSE S, TIBAYRENC M. Population structure and genetic typing of Trypanosoma cruzi: the agent of Chagas' disease: a multilocus enzyme electrophoresis approach. Parasitology 2000; 120: 513-26.
15. ACUÑA M, LLOP E, ROTHHAMMER F. Genetic composition of Chilean population: rural communities of Elqui, Limari and Choapa valleys. Rev Méd Chile 2000; 128: 563-600.