In vitro desaturation and elongation of rumenic acid by rat liver microsomes

Lipids

Volumn 37, Issue 11, 2002, Pages 1039-1045

  Berdeaux, O ^a   Gnadig S ^a   Chardigny, J M ^a   Loreau, O ^b   Noel J P ^b   Sebedio J L ^a  

^a CEMAGREF   (France)

^b CEA SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; ISOMERS; NUTRITION; SUBSTRATES;

LIVER MICROSOMES;

LIPIDS;

CONJUGATED LINOLEIC ACID; LINOLEIC ACID; RUMENIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY ACID DESATURATION; FATTY ACID METABOLISM; ISOMERISM; ISOTOPE LABELING; LIVER MICROSOME; MALE; NONHUMAN; NUTRITION; RAT;

ANIMALS; DIET, FAT-RESTRICTED; FATTY ACID DESATURASES; FATTY ACIDS, MONOUNSATURATED; FATTY ACIDS, UNSATURATED; LINOLEIC ACIDS, CONJUGATED; LIVER; MICROSOMES, LIVER; RATS;

ANIMALIA;

EID: 0346034685     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-002-0998-8     Document Type: Article

References (26)

1. Kepler, C.R., and Tove, S.B. (1967) Biohydrogenation of Unsaturated Fatty Acids, J. Biol. Chem. 242, 5686-5692.
2. Hughes, P.E., Hunter, W.J., and Tove, S.B. (1982) Biohydrogenation of Unsaturated Fatty Acids: Purification and Properties of cis-9, trans-11-Octadecadienoate Reductase, J. Biol. Chem. 257, 3643-3649.
3. Griinari, J.M., and Bauman, D.E. (1999) Biosynthesis of Conjugated Linoleic Acid and Its Incorporation into Meat and Milk in Ruminants, in Advances in Conjugated Linoleic Acid Research, Vol. 1 (Yurawecz, M.P., Mossoba, M.M., Kramer, J.K.G., Pariza, M.W. and Nelson, G.J., eds.), pp. 180-200, AOCS Press, Champaign.
4. Cawood, P., Wickens, D.G., Iversen, S.A., Braganza, J.M., and Dormandy, T.L. (1983) The Nature of Diene Conjugation in Human Serum, Bile and Duodenal Juice, FEBS Lett. 162, 239-243.
5. Banni, S., Day, B.W., Evans, R.W., Corongiu, F., and Lombardi, B. (1994) Liquid Chromatographic-Mass Spectrometric Analysis of Conjugated Diene Fatty Acids in a Partially Hydrogenated Fat, J. Am. Oil Chem. Soc. 71, 1321-1325.
6. Banni, S., and Martin, J.C. (1998) Conjugated Linoleic Acid and Metabolites, in Trans Fatty Acids in Human Nutrition (Sébédio, J.L., and Christie, W.W., eds.), pp. 261-302, The Oily Press, Dundee.
7. Sébédio, J.L., Gnädig, S., and Chardigny, J.M. (1999) Recent Advances in Conjugated Linoleic Acid, Curr. Opin. Clin. Nutr. Metab. Care 2, 499-506.
8. Pariza, M.W., Park, Y., and Cook, M.E. (2000) Mechanisms of Action of Conjugated Linoleic Acid: Evidence and Speculation, Proc. Soc. Exp. Biol. Med. 223, 8-13.
9. Park, Y., Albright, K.J., Liu, W., Storkson, J.M., Cook, M.E., and Pariza, M.W. (1997) Effect of Conjugated Linoleic Acid on Body Composition in Mice, Lipids 32, 853-858.
10. Dugan, M.E.R., Aalhus, J.L., Schaefer, A.L., and Kramer, J.K.G. (1997) The Effect of Conjugated Linoleic Acid on Fat to Lean Repartitioning and Feed Conversion in Pigs, Can. J. Anim. Sci. 77, 723-725.
11. Banni, S., Angioni, E., Casu, V., Melis, M.P., Carta, G., Corongiu, F.P., Thompson, H., and Ip, C. (1999) Decrease in Linoleic Acid Metabolites as a Potential Mechanism in Cancer Risk Reduction by Conjugated Linoleic Acid, Carcinogenesis 20, 1019-1024.
12. Sébédio, J.L., Juaneda, P., Dobson, G., Ramilison, I., Martin, J.C., Chardigny, J.M., and Christie, W.W. (1997) Metabolites of Conjugated Isomers of Linoleic Acid (CLA) in the Rat, Biochim. Biophys. Acta 1345, 5-10.
13. Sébédio, J.L., Angioni, E., Chardigny, J.M., Grégoire, S., Juanéda, P., and Berdeaux, O. (2001) The Effect of Conjugated Linoleic Acid Isomers on Fatty Acid Profiles of Liver and Adipose Tissues and Their Conversion to Isomers of 16:2 and 18:3 Conjugated Fatty Aids in Rats, Lipids 36, 575-582.
14. Belury, M.A., and Kempa-Steczko, A. (1997) Conjugated Linoleic Acid Modulates Hepatic Lipid Composition in Mice, Lipids 32, 199-204.
15. Bretillon, L., Chardigny, J.M., Grégoire, S., Berdeaux, O., and Sébédio, J.L. (1999) Effects of Conjugated Linoleic Acid Isomers on the Hepatic Microsomal Desaturation Activities in vitro, Lipids 34, 965-969.
16. 14C] Conjugated Linoleic Acid Isomers, Chem. Phys. Lipids 110, 57-67.
17. 14C]-Radiolabeled Analogs, Chem. Phys. Lipids 112, 121-135.
18. Berdeaux, O., Blond, J.P., Bretillon, L., Chardigny, J.M., Mairot, T., Vatèle, J.M., Poullain, D., and Sébédio, J.L. (1998) In vitro Desaturation or Elongation of Monotrans Isomers of Linoleic Acid by Rat Liver Microsomes, Mol. Cell. Biochem. 185, 17-25.
19. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951) Protein Measurement with the Folin Phenol Reagent, J. Biol. Chem. 193, 265-275.
20. Mohrhauer, H., Christiansen, K., Gan, M.V., Deubic, M., and Holman, R.T. (1967) Chain Elongation of Linoleic Acid and Its Inhibition by Other Fatty Acids in vitro, J. Biol. Chem. 242, 4507-4514.
21. Mohrhauer, H., and Holman, R. (1963) The Effect of Dose Level of Essential Fatty Acids upon Fatty Acid Composition of the Rat Liver, J. Lipid Res. 4, 151-159.
22. Cook, H.W. (1991) Fatty Acid Desaturation and Chain Elongation in Eucaryotes, in Biochemistry of Lipids, Lipoproteins and Membranes (Vance, D.E., and Vance, J. eds.), pp. 141-169, Elsevier Science, New York.
23. Cao, J., Blond, J.P., and Bézard, J. (1993) Inhibition of Fatty Acid Δ6- and Δ5-Desaturation by Cyclopropene Fatty Acids in Rat Liver Microsomes, Biochim. Biophys. Acta 1210, 27-34.
24. Sébédio, J.L. (1994) Classical Chemical Techniques for Fatty Acid Analysis, in New Trends in Lipids and Lipoprotein Analysis (Sébédio, J.L., and Perkins, E.G., eds.), pp. 277-289, AOCS Press, Champaign.
25. Brenner, R.R. (1971) The Desaturation Step in Animal Biosynthesis of Polyunsaturated Fatty Acids, Lipids 6, 567-571.
26. Banni, S., Carta, G., Angioni, E., Murru, E., Scanu, P., Melis, M.P., Bauman, D.E., Fischer, S.M., and Ip, C. (2001) Distribution of Conjugated Linoleic Acid and Metabolites in Different Lipid Fractions in the Rat Liver, J. Lipid Res. 42, 1056-1061.