In vivo PET imaging of gene expression in Parkinsonian monkeys [2]

Molecular Therapy

Volumn 8, Issue 6, 2003, Pages 873-875

  Eberling, J L ^a,b   Cunningham, J ^c   Pivirotto, P ^d   Bringas, J ^d   Daadi, M M ^d   Bankiewicz, K S ^d  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Avigen Inc   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ADENOVIRUS VECTOR; AMINO ACID DECARBOXYLASE; CARBIDOPA PLUS LEVODOPA; CHLORIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD SAMPLING; CAUDATE NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; GENETIC TRANSDUCTION; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; LETTER; MONKEY; NONHUMAN; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PUTAMEN; RADIATION DETECTION; REGRESSION ANALYSIS; REPORTER GENE; SCORING SYSTEM; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALIA; PARKINSONIA;

EID: 0346025624     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.09.013     Document Type: Letter

References (7)

1. Blasberg, R (2002). PET imaging of gene expression. Eur. J. Cancer 38: 2137-2146.
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3. Bankiewicz, K. S., et al. (1986). Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life Sci. 39: 7-16.
4. Eberling, J. L., et al. (1998). A novel MPTP primate model of Parkinson's disease: neurochemical and clinical changes. Brain Res. 805: 259-262.
5. de Vries, E. F., and Vaalburg, W. (2002). Positron emission tomography: measurement of transgene expression. Methods 27: 234-241.
6. Green, L. A., et al. (1998). Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose. J. Nucl. Med. 39: 729-734.
7. Kordower, J. H., et al. (2000). Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290: 767-773.