Glutamate increases toxicity of inorganic lead in GT1-7 neurons: Partial protection induced by flunarizine

Archives of Toxicology

Volumn 77, Issue 12, 2003, Pages 663-671

  Loikkanen, Jarkko ^a   Naarala, Jonne ^a   Vähäkangas, Kirsi H ^a   Savolainen, Kai M ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

Author keywords

Calcium channels; Glutamate; Glutathione; Lead; Neurons; Reactive oxygen species

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM CHANNEL T TYPE; FLUNARIZINE; GLUTAMIC ACID; GLUTATHIONE; LEAD; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANION EXCHANGE; ARTICLE; CELL LEVEL; CELL VIABILITY; CYTOTOXICITY; DRUG EXPOSURE; HYPOTHALAMUS; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FLUNARIZINE; GLUTAMIC ACID; GLUTATHIONE; HYPOTHALAMUS; LEAD; MICE; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, GLUTAMATE; VERAPAMIL;

ANIMALIA;

EID: 0346008026     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0498-z     Document Type: Article

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