Grevellin Analogs with Affinity to the N-Methyl-D-aspartate (Glycine Site) Receptor, a Novel Lead Structure

Archiv der Pharmazie

Volumn 333, Issue 7, 2000, Pages 211-216

  Poschenrieder, Hermann ^a   Höfner, Georg ^a   Stachel, Hans Dietrich ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

NMDA (glycine site) receptor affinity; Piperidine 2,3,5 triones; Ring enlargement; Spirooxiranes; 3H MDL 105,519 displacement

Indexed keywords

3 (2 CARBOXY 2 PHENYLETHENYL) 4,6 DICHLORO 1H INDOLE 2 CARBOXYLIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; GLYCINE RECEPTOR; INDOLE DERIVATIVE; KETONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PIPERIDINE DERIVATIVE;

ANIMAL; ARTICLE; BINDING COMPETITION; BRAIN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; STRUCTURE ACTIVITY RELATION; SWINE; SYNTHESIS;

ANIMALS; BINDING, COMPETITIVE; BRAIN; EXCITATORY AMINO ACID ANTAGONISTS; INDOLES; KETONES; MOLECULAR STRUCTURE; PIPERIDINES; RECEPTORS, GLYCINE; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 0345850073     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4184(20007)333:7<211::AID-ARDP211>3.0.CO;2-9     Document Type: Article

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