메뉴 건너뛰기




Volumn 53, Issue 1, 2004, Pages 143-148

Monitoring target reduction in hepatic venous pressure gradient during pharmacological therapy of portal hypertension: A close look at the evidence

Author keywords

[No Author keywords available]

Indexed keywords

NADOLOL; PROPRANOLOL;

EID: 0345830638     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.53.1.143     Document Type: Review
Times cited : (44)

References (50)
  • 1
    • 0029134073 scopus 로고
    • The treatment of portal hypertension: A meta-analytic review
    • D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a meta-analytic review. Hepatology 1995;22:332-54.
    • (1995) Hepatology , vol.22 , pp. 332-354
    • D'Amico, G.1    Pagliaro, L.2    Bosch, J.3
  • 2
    • 0033403439 scopus 로고    scopus 로고
    • Endoscopic treatment for portal hypertension
    • DeFranchis R, Primignani M. Endoscopic treatment for portal hypertension. Semin Liver Dis 1999;19:439-55.
    • (1999) Semin Liver Dis , vol.19 , pp. 439-455
    • DeFranchis, R.1    Primignani, M.2
  • 3
    • 0035083039 scopus 로고    scopus 로고
    • A meta-analysis of endoscopic variceal ligation fat primary prophylaxis of esophageal bleeding
    • Imperiale TF, Chalasani N. A meta-analysis of endoscopic variceal ligation fat primary prophylaxis of esophageal bleeding. Hepatology 2000;33:1003-4.
    • (2000) Hepatology , vol.33 , pp. 1003-1004
    • Imperiale, T.F.1    Chalasani, N.2
  • 4
    • 0035975395 scopus 로고    scopus 로고
    • Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleeding
    • Villanueva C, Minana J, Ortiz J, et al. Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleeding. N Engl J Med 2001;345:647-55.
    • (2001) N Engl J Med , vol.345 , pp. 647-655
    • Villanueva, C.1    Minana, J.2    Ortiz, J.3
  • 5
    • 0036731118 scopus 로고    scopus 로고
    • Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding
    • Lo G-H, Chen W-C, Chen M-H, et al. Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding. Gastroenterology 2002;123:728-34.
    • (2002) Gastroenterology , vol.123 , pp. 728-734
    • Lo, G.-H.1    Chen, W.-C.2    Chen, M.-H.3
  • 6
    • 0036788252 scopus 로고    scopus 로고
    • A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis
    • Patch D, Sabin CA, Goulis J, et al. A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis. Gastroenterology 2002;123:1013-19.
    • (2002) Gastroenterology , vol.123 , pp. 1013-1019
    • Patch, D.1    Sabin, C.A.2    Goulis, J.3
  • 7
    • 0036895678 scopus 로고    scopus 로고
    • A la carte or menu fixe: Improving pharmacologic therapy of portal hypertension
    • Bosch J. A la carte or menu fixe: improving pharmacologic therapy of portal hypertension. Hepatology 2002;36:1330-2.
    • (2002) Hepatology , vol.36 , pp. 1330-1332
    • Bosch, J.1
  • 8
    • 10644288439 scopus 로고    scopus 로고
    • Current management of portal hypertension
    • Bosch J, Abraldes JG, Groszmann R. Current management of portal hypertension. J Hepatol 2003;38(suppl 1):S54-68.
    • (2003) J Hepatol , vol.38 , Issue.1 SUPPL.
    • Bosch, J.1    Abraldes, J.G.2    Groszmann, R.3
  • 9
    • 0037443978 scopus 로고    scopus 로고
    • Prevention of variceal bleeding
    • Bosch J, García-Pagán JC. Prevention of variceal bleeding. Lancet 2003;361:952-4.
    • (2003) Lancet , vol.361 , pp. 952-954
    • Bosch, J.1    García-Pagán, J.C.2
  • 10
    • 0037248022 scopus 로고    scopus 로고
    • Hepatic venous pressure gradient measurements to assess response to primary prophylaxis in patients with cirrhosis: A decision analytical study
    • Hicken BL, Sharara AI, Abrams GA, et al. Hepatic venous pressure gradient measurements to assess response to primary prophylaxis in patients with cirrhosis: a decision analytical study. Aliment Pharmacol Ther 2003;17:145-53.
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 145-153
    • Hicken, B.L.1    Sharara, A.I.2    Abrams, G.A.3
  • 11
    • 0025016059 scopus 로고
    • Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage
    • Groszmann RJ, Bosch J, Grace ND, et al. Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology 1990;99:1401-7.
    • (1990) Gastroenterology , vol.99 , pp. 1401-1407
    • Groszmann, R.J.1    Bosch, J.2    Grace, N.D.3
  • 12
    • 0029839762 scopus 로고    scopus 로고
    • Prognostic value of hepatic venous pressure gradient measurements in alcoholic cirrhosis: A 10-year prospective study
    • Vorobioff J, Groszmann RJ, Pibacea E, et al. Prognostic value of hepatic venous pressure gradient measurements in alcoholic cirrhosis: a 10-year prospective study. Gastroenterology 1996;111:701-9.
    • (1996) Gastroenterology , vol.111 , pp. 701-709
    • Vorobioff, J.1    Groszmann, R.J.2    Pibacea, E.3
  • 13
    • 0036896603 scopus 로고    scopus 로고
    • "A la carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding
    • Bureau C, Péron JM, Alric L, et al. "A la carte" treatment of portal hypertension: adapting medical therapy to hemodynamic response for the prevention of bleeding. Hepatology 2002;36:1361-6.
    • (2002) Hepatology , vol.36 , pp. 1361-1366
    • Bureau, C.1    Péron, J.M.2    Alric, L.3
  • 14
    • 0036789675 scopus 로고    scopus 로고
    • Endoscopic variceal banding vs. pharmacological therapy for the prevention of recurrent variceal haemorrhage: What makes the difference
    • Groszmann RJ, Garcia-Tsao G. Endoscopic variceal banding vs. pharmacological therapy for the prevention of recurrent variceal haemorrhage: what makes the difference. Gastroenterology 2002;123:1388-91.
    • (2002) Gastroenterology , vol.123 , pp. 1388-1391
    • Groszmann, R.J.1    Garcia-Tsao, G.2
  • 15
    • 0028790232 scopus 로고
    • Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis
    • Feu F, Garcia-Pagan JC, Bosch J, et al. Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet 1995;346:1056-9.
    • (1995) Lancet , vol.346 , pp. 1056-1059
    • Feu, F.1    Garcia-Pagan, J.C.2    Bosch, J.3
  • 16
    • 0030003919 scopus 로고    scopus 로고
    • Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding
    • Villanueva C, Balanzo J, Novella MT, et al. Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding. N Engl J Med 1996;334:1624-9.
    • (1996) N Engl J Med , vol.334 , pp. 1624-1629
    • Villanueva, C.1    Balanzo, J.2    Novella, M.T.3
  • 17
    • 0032103874 scopus 로고    scopus 로고
    • Clinical vs hemodynamic response to drugs in portal hypertension
    • McCormick PA, Patch D, Greenslade L, et al. Clinical vs hemodynamic response to drugs in portal hypertension. J Hepatol 1998;28:1015-19.
    • (1998) J Hepatol , vol.28 , pp. 1015-1019
    • McCormick, P.A.1    Patch, D.2    Greenslade, L.3
  • 18
    • 0026007704 scopus 로고
    • Importance of the 1-month-effect of nadolol on portal pressure in predicting failure of prevention of rebleeding in cirrhosis
    • Sacerdoti D, Merkel C, Gatta A. Importance of the 1-month-effect of nadolol on portal pressure in predicting failure of prevention of rebleeding in cirrhosis. J Hepatol 1991;12:124-5.
    • (1991) J Hepatol , vol.12 , pp. 124-125
    • Sacerdoti, D.1    Merkel, C.2    Gatta, A.3
  • 19
    • 0031012853 scopus 로고    scopus 로고
    • Hepatic venous pressure measurement: An old test as a new prognostic marker in cirrhosis?
    • Armonis A, Patch D, Burroughs AK. Hepatic venous pressure measurement: an old test as a new prognostic marker in cirrhosis? Hepatology 1997;25:245-8.
    • (1997) Hepatology , vol.25 , pp. 245-248
    • Armonis, A.1    Patch, D.2    Burroughs, A.K.3
  • 20
    • 0022626894 scopus 로고
    • Assessment of short-term prognosis after variceal bleeding in patients with alcoholic cirrhosis by early measurement of portohepotic gradient
    • Vinel JP, Cassigneul J, Levade M, et al. Assessment of short-term prognosis after variceal bleeding in patients with alcoholic cirrhosis by early measurement of portohepotic gradient. Hepatology 1986;6:116-17.
    • (1986) Hepatology , vol.6 , pp. 116-117
    • Vinel, J.P.1    Cassigneul, J.2    Levade, M.3
  • 21
    • 0021068302 scopus 로고
    • Controlled trial of propranolol for the prevention of recurrent variceal hemorrhage in patients with cirrhosis
    • Burroughs AK, Jenkins WJ, Sherlock S, et al. Controlled trial of propranolol for the prevention of recurrent variceal hemorrhage in patients with cirrhosis. N Engl J Med 1983;309:1539-42.
    • (1983) N Engl J Med , vol.309 , pp. 1539-1542
    • Burroughs, A.K.1    Jenkins, W.J.2    Sherlock, S.3
  • 22
    • 18244380855 scopus 로고    scopus 로고
    • TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: A randomized controlled trial
    • Escorsell A, Bañares R, García-Pagán JC, et al. TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial. Hepatology 2002;35:385-92.
    • (2002) Hepatology , vol.35 , pp. 385-392
    • Escorsell, A.1    Bañares, R.2    García-Pagán, J.C.3
  • 23
    • 0032870515 scopus 로고    scopus 로고
    • Prognostic value of early measurements of portal pressure in acute variceal bleeding
    • Moitinho E, Escorsell A, Bandi JC, et al. Prognostic value of early measurements of portal pressure in acute variceal bleeding. Gastroenterology 1999;117:626-31.
    • (1999) Gastroenterology , vol.117 , pp. 626-631
    • Moitinho, E.1    Escorsell, A.2    Bandi, J.C.3
  • 24
    • 0023265161 scopus 로고
    • Failure of haemodynamic measurements to predict recurrent gastrointestinal bleeding in cirrhotic patients receiving propranolol
    • Valla D, Jiron MI, Poynard T, et al. Failure of haemodynamic measurements to predict recurrent gastrointestinal bleeding in cirrhotic patients receiving propranolol. J Hepatol 1987;5:144-8.
    • (1987) J Hepatol , vol.5 , pp. 144-148
    • Valla, D.1    Jiron, M.I.2    Poynard, T.3
  • 25
    • 0033054895 scopus 로고    scopus 로고
    • Single portal pressure measurement predicts survival in cirrhotic patients with recent bleeding
    • Patch D, Armonis A, Sabin K, et al. Single portal pressure measurement predicts survival in cirrhotic patients with recent bleeding. Gut 1999;44:264-9.
    • (1999) Gut , vol.44 , pp. 264-269
    • Patch, D.1    Armonis, A.2    Sabin, K.3
  • 26
    • 0347791384 scopus 로고
    • Prognostic significance of systemic and portal haemodynamic parameters in patients with cirrhosis and previous variceal bleeding
    • Vlavianos P, Gimson ES, Hayllar K, et al. Prognostic significance of systemic and portal haemodynamic parameters in patients with cirrhosis and previous variceal bleeding. Gut 1990;31:592A.
    • (1990) Gut , vol.31
    • Vlavianos, P.1    Gimson, E.S.2    Hayllar, K.3
  • 27
    • 0033899365 scopus 로고    scopus 로고
    • Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: A hemodynamic evaluation
    • De BK, Sen S, Biswas PK, et al. Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: a hemodynamic evaluation. Am J Gastroenterol 2000;95:2023-8.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2023-2028
    • De, B.K.1    Sen, S.2    Biswas, P.K.3
  • 28
    • 0034096404 scopus 로고    scopus 로고
    • Predictive value of the variceal pressure response to continued pharmacological therapy in patients with cirrhosis and portal hypertension
    • Escorsell A, Bordas JM, Castañeda B, et al. Predictive value of the variceal pressure response to continued pharmacological therapy in patients with cirrhosis and portal hypertension. Hepatology 2000;31:1061-7.
    • (2000) Hepatology , vol.31 , pp. 1061-1067
    • Escorsell, A.1    Bordas, J.M.2    Castañeda, B.3
  • 29
    • 0031003291 scopus 로고    scopus 로고
    • The portal pressure response to β-blockade is greater in cirrhotic patients without varices than in those with varices
    • Escorsell A, Ferayorni L, Bosch J, et al. The portal pressure response to β-blockade is greater in cirrhotic patients without varices than in those with varices. Gastroenterology 1997;112:2012-16.
    • (1997) Gastroenterology , vol.112 , pp. 2012-2016
    • Escorsell, A.1    Ferayorni, L.2    Bosch, J.3
  • 30
    • 0037382804 scopus 로고    scopus 로고
    • Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis
    • Abraldes JG, Tarantino I, Turnes J, et al. Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis. Hepatology 2003;37:902-8.
    • (2003) Hepatology , vol.37 , pp. 902-908
    • Abraldes, J.G.1    Tarantino, I.2    Turnes, J.3
  • 31
    • 0033765377 scopus 로고    scopus 로고
    • The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis
    • Merkel C, Bolognesi M, Sacerdoti D, et al. The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis. Hepatology 2000;32:930-4.
    • (2000) Hepatology , vol.32 , pp. 930-934
    • Merkel, C.1    Bolognesi, M.2    Sacerdoti, D.3
  • 32
    • 0035188533 scopus 로고    scopus 로고
    • Propranolol for the prevention of first esophageal variceal hemorrhage: A lifetime commitment?
    • Abraczinskas DR, Ookubo R, Grace ND, et al. Propranolol for the prevention of first esophageal variceal hemorrhage: a lifetime commitment? Hepatology 2001;34:1096-102.
    • (2001) Hepatology , vol.34 , pp. 1096-1102
    • Abraczinskas, D.R.1    Ookubo, R.2    Grace, N.D.3
  • 33
    • 0036668697 scopus 로고    scopus 로고
    • Intrahepatic heterogeneity of hepatic venous pressure gradient in human cirrhosis
    • Keiding S, Vilstrup H. Intrahepatic heterogeneity of hepatic venous pressure gradient in human cirrhosis. Scand J Gastroenterol 2002;37:960-4.
    • (2002) Scand J Gastroenterol , vol.37 , pp. 960-964
    • Keiding, S.1    Vilstrup, H.2
  • 34
    • 0021797737 scopus 로고
    • Propranolol for portal hypertension. Evaluation of therapeutic response by direct measurement of portal vein pressure
    • Rector WG. Propranolol for portal hypertension. Evaluation of therapeutic response by direct measurement of portal vein pressure. Arch Intern Med 1985;145:648-50.
    • (1985) Arch Intern Med , vol.145 , pp. 648-650
    • Rector, W.G.1
  • 35
    • 0014850963 scopus 로고
    • Comparison of free portal venous pressure and wedged hepatic venous pressure in patients with cirrhosis of the liver
    • Viallet A, Joly JG, Marleau D, et al. Comparison of free portal venous pressure and wedged hepatic venous pressure in patients with cirrhosis of the liver. Gastroenterology 1970;59:372-5.
    • (1970) Gastroenterology , vol.59 , pp. 372-375
    • Viallet, A.1    Joly, J.G.2    Marleau, D.3
  • 36
    • 0028001667 scopus 로고
    • Wedged hepatic venous pressure reflects portal venous pressure during vasoactive drug administration in non-alcoholic cirrhosis
    • Iwao T, Toyonaga A, Ikegami M, et al. Wedged hepatic venous pressure reflects portal venous pressure during vasoactive drug administration in non-alcoholic cirrhosis. Dig Dis Sci 1994;39:2439-44.
    • (1994) Dig Dis Sci , vol.39 , pp. 2439-2444
    • Iwao, T.1    Toyonaga, A.2    Ikegami, M.3
  • 37
    • 0032717177 scopus 로고    scopus 로고
    • Wedged hepatic venous pressure adequately reflects portal pressure in hepatitis C virus-related cirrhosis
    • Perelló A, Escorsell A, Bru C, et al. Wedged hepatic venous pressure adequately reflects portal pressure in hepatitis C virus-related cirrhosis. Hepatology 1999;30:1393-7.
    • (1999) Hepatology , vol.30 , pp. 1393-1397
    • Perelló, A.1    Escorsell, A.2    Bru, C.3
  • 38
    • 0017740763 scopus 로고
    • Direct transhepatic measurement of portal vein pressure using a thin needle. Comparison with wedged hepatic vein pressure
    • Boyer TD, Triger DR, Horisawa M, et al. Direct transhepatic measurement of portal vein pressure using a thin needle. Comparison with wedged hepatic vein pressure. Gastroenterology 1977;72:584-9.
    • (1977) Gastroenterology , vol.72 , pp. 584-589
    • Boyer, T.D.1    Triger, D.R.2    Horisawa, M.3
  • 39
    • 0018381616 scopus 로고
    • Wedged and free hepatic venous pressure measured with a balloon catheter
    • Groszmann RJ, Glickman M, Blei AT, et al. Wedged and free hepatic venous pressure measured with a balloon catheter. Gastroenterology 1979;76:253-8.
    • (1979) Gastroenterology , vol.76 , pp. 253-258
    • Groszmann, R.J.1    Glickman, M.2    Blei, A.T.3
  • 40
    • 0024374170 scopus 로고
    • Comparison between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related cirrhosis
    • Lin HC, Tsai YT, Lee FY, et al. Comparison between portal vein pressure and wedged hepatic vein pressure in hepatitis B-related cirrhosis. J Hepatol 1989;9:326-30.
    • (1989) J Hepatol , vol.9 , pp. 326-330
    • Lin, H.C.1    Tsai, Y.T.2    Lee, F.Y.3
  • 41
    • 0014873661 scopus 로고
    • Measurement of portal pressure and its clinical application
    • Reynolds TB, Ito S, Iwatsuki S. Measurement of portal pressure and its clinical application. Am J Med 1970;49:649-57.
    • (1970) Am J Med , vol.49 , pp. 649-657
    • Reynolds, T.B.1    Ito, S.2    Iwatsuki, S.3
  • 42
    • 0000600879 scopus 로고
    • Spontaneous decrease in portal pressure with clinical improvement in cirrhosis
    • Reynolds TB, Geller HM, Kuzma OT, et al. Spontaneous decrease in portal pressure with clinical improvement in cirrhosis. N Engl J Med 1960;263:734-9.
    • (1960) N Engl J Med , vol.263 , pp. 734-739
    • Reynolds, T.B.1    Geller, H.M.2    Kuzma, O.T.3
  • 43
    • 0026081958 scopus 로고
    • Reduction in hepatic venous pressure gradient as a consequence of volume contraction due to chronic administration of spironolactone in patients with cirrhosis and no ascites
    • Okumura H, Arakami T, Katsuta Y, et al. Reduction in hepatic venous pressure gradient as a consequence of volume contraction due to chronic administration of spironolactone in patients with cirrhosis and no ascites. Am J Gastroenterol 1991;86:46-52.
    • (1991) Am J Gastroenterol , vol.86 , pp. 46-52
    • Okumura, H.1    Arakami, T.2    Katsuta, Y.3
  • 44
    • 0028212762 scopus 로고
    • Effects of low-sodium diet and spironolactone on portal pressure in patients with compensated cirrhosis
    • García-Pagán J, Salmeron J, Feu F, et al. Effects of low-sodium diet and spironolactone on portal pressure in patients with compensated cirrhosis. Hepatology 1994;19:1095-9.
    • (1994) Hepatology , vol.19 , pp. 1095-1099
    • García-Pagán, J.1    Salmeron, J.2    Feu, F.3
  • 45
    • 0031903025 scopus 로고    scopus 로고
    • Chronic splanchnic hemodynamic effects of spironolactone with unrestricted sodium diet in patients with compensated cirrhosis
    • Sugano S, Kawafune T, Okajima T, et al. Chronic splanchnic hemodynamic effects of spironolactone with unrestricted sodium diet in patients with compensated cirrhosis. Dig Dis Sci 1998;43:893-7.
    • (1998) Dig Dis Sci , vol.43 , pp. 893-897
    • Sugano, S.1    Kawafune, T.2    Okajima, T.3
  • 46
    • 0029869773 scopus 로고    scopus 로고
    • The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites
    • Nevens F, Lijnen P, VanBilloen H, et al. The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. Hepatology 1996;23:1047-52.
    • (1996) Hepatology , vol.23 , pp. 1047-1052
    • Nevens, F.1    Lijnen, P.2    VanBilloen, H.3
  • 47
    • 0037492418 scopus 로고    scopus 로고
    • Prevention of variceal rebleeding
    • Thalheimer U, Mela M, Patch D, et al. Prevention of variceal rebleeding. Lancet 2003;361:2244-5.
    • (2003) Lancet , vol.361 , pp. 2244-2245
    • Thalheimer, U.1    Mela, M.2    Patch, D.3
  • 48
    • 0025906655 scopus 로고
    • Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study
    • Garcia-Pagan JC, Feu F, Bosch J, et al. Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study. Ann Intern Med 1991;114:869-73.
    • (1991) Ann Intern Med , vol.114 , pp. 869-873
    • Garcia-Pagan, J.C.1    Feu, F.2    Bosch, J.3
  • 49
    • 0034074123 scopus 로고    scopus 로고
    • Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding
    • Gournay J, Masliah C, Martin T, et al. Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding. Hepatology 2000;31:1239-45.
    • (2000) Hepatology , vol.31 , pp. 1239-1245
    • Gournay, J.1    Masliah, C.2    Martin, T.3
  • 50
    • 0001992186 scopus 로고    scopus 로고
    • Isosorbide mononitrate (IMN) with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double-blind placebo-controlled randomised trial
    • Patti R, D'Amico G, Pasta L, et al. Isosorbide mononitrate (IMN) with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double-blind placebo-controlled randomised trial. J Hepatol 1999;30(suppl 1):81A.
    • (1999) J Hepatol , vol.30 , Issue.1 SUPPL.
    • Patti, R.1    D'Amico, G.2    Pasta, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.