Expression of a novel neuropeptide, NVGTLARDFQLPIPNamide, in the larval and adult brain of Drosophila melanogaster

Journal of Neurochemistry

Volumn 88, Issue 2, 2004, Pages 311-319

  Verleyen, Peter ^a,d   Baggerman, Geert ^a   Wiehart, Ursula ^b   Schoeters, Eric ^c   Van Lommel, Alfons ^a   De Loof, Arnold ^a   Schoofs, Liliane ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c Laboratory of Entomology   (Belgium)

^d Zoological Institute   (Belgium)

Author keywords

Drosophila; FMRFamide; IPNamide; Peptides; Whole mount immunocytochemistry

Indexed keywords

ASPARAGINYLVALYLGLYCYLTHREONYLLEUCYLALANYLARGINYLASPARTYLPHENYLALANYLGLUTAM INYLLEUCYLPROLYLISOLEUCYLPROLYLASPARAGINAMIDE; BRAIN EXTRACT; NEUROPEPTIDE; PEPTIDE; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; THREONYLPROLYLALANYLGLUTAMYLASPARTYLPHENYLALANYLMETHIONYLARGINYLPHENYLALANI NAMIDE; UNCLASSIFIED DRUG;

ANOPHELES GAMBIAE; ARTICLE; BRAIN; CAPILLARY CHROMATOGRAPHY; CONFOCAL MICROSCOPY; DATA BASE; DROSOPHILA MELANOGASTER; ESOPHAGUS; FMRFAMIDE GENE; GENE; GENOME; GENOMICS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INSECT GENETICS; LARVA; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NANOFILTRATION; NANOFLOW CAPILLARY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDOMICS; PHOTOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; SENSORY STIMULATION; SEQUENCE HOMOLOGY; TANDEM MASS SPECTROMETRY;

ANOPHELES GAMBIAE; ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MELANOGASTER;

EID: 0345825930     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02161.x     Document Type: Article

References (28)

1. Adams M. D., Celniker S. E., Holt R. A., Evans C. A., Gocayne J. D., Amanatides P. G., Scherer S. E., Li P. W., Hoskins R. A., Galle R. F. et al. (2000) The genome sequence of Drosophila melanogaster. Science 287, 2185-2195.
2. Baggerman G., Cerstiaens A., De Loof A. and Schoofs L. (2002) Peptidomics of the larval Drosophila melanogaster central nervous system. J. Biol. Chem. 277, 40368-40374.
3. Clynen E., Baggerman G., Veelaert D., Van der Cerstiaens A. H. D., Harthoom L., Derua R., Waelkens E., De Loof A. and Schoofs L. (2001) Peptidomics of the pars intercerebralis-corpus cardiacum complex of the migratory locust, Locusta migratoria. Eur. J. Biochem. 268, 1929-1939.
4. Clynen E., Huybrechts J., De Loof A. and Schoofs L. (2003) Mass spectrometric analysis of the perisympathetic organs in locusts: identification of novel periviscerokinins. Biochem. Biophys. Res. Comm. 300, 422-428.
5. De Loof A., Baggennan G., Breuer M., Claeys I., Cerstiaens A., Clynen E., Janssen T., Schoofs L. and Vanden Broeck J. (2001) Gonadotropins in insects: an overview. Arch. Insect Biochem. Physiol. 47, 129-138.
6. Duttlinger A., Mispelon M. and Nichols R. (2003) The structure of the FMRFamide receptor and activity of the cardioexcitatory neuropeptide are conserved in mosquito. Neuropeptides 37, 120-126.
7. Hewes R. S. and Taghert P. H. (2001) Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. Genome Res. 11, 1126-1142.
8. Hewes R. S., Snowdeal E. C. III, Saitoe M. and Taghert P. H. (1998) Functional redundancy of FMRFamide-related peptides at the Drosophila larval neuromuscular junction. J. Neurosci. 18, 7138-7151.
9. Holman G. M., Nachman R. J., Schoofs L., Hayes T. K., Wright M. S. and De Loof A. (1991) The Leucophaea maderae hindgut preparation: a rapid and sensitive bioassay tool for the isolation of insect myotropins of other insect species. Insect Biochem. 21, 107-112.
10. Johnson E., Ringo J. and Dowse H. (2000) Native and heterologous neuropeptides are cardioactive in Drosophila melanogaster. J. Insect Physiol. 46, 1229-1236.
11. Kaminski S., Orlowski E., Berry K. and Nichols R. (2002) The effects of three Drosophila melanogaster myotropins on the frequency of foregut contractions differ. J. Neurogenet. 16, 125-134.
12. Lundquist T. and Nassel D. R. (1990) Substance P-, FMRFamide-, and gastrin/cholecystokinin-like immunoreactive neurons in the thoraco-abdominal ganglia of the flies Drosophila and Calliphora. J. Comp. Neurol. 294, 161-178.
13. McCormick J., Lim I. and Nichols R. (1999) Neuropeptide precursor processing detected by triple immunolabeling. Cell Tissue Res. 297, 197-202.
14. Meng X., Wahlstrom G., Immonen T., Kolmer M., Tirronen M., Predel R., Kalkkinen N., Heino T. I., Sariola H. and Roos C. (2002) The Drosophila hugin gene codes for myostimulatory and ecdysis-modifying neuropeptides. Mech. Dev 117, 5-13.
15. Nassel D. R. (2002) Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones. Prog. Neurobiol. 68, 1-84.
16. Nichols R. (1992) Isolation and structural characterization of Drosophila TDVDHVFLRFamide and FMRFamide-containing neural peptides. J. Mol. Neurosci. 3, 213-218.
17. Nichols R. (2002) Signaling pathways and physiological functions of Drosophila melanogaster FMRFamide-related peptides. Annu. Rev. Entomol. 48, 485-503.
18. Nichols R., McCormick J., Cohen M., Howe E., Jean C., Paisley K. and Rosario C. (1999a) Differential processing of neuropeptides influences Drosophila heart rate. J. Neurogenet. 13, 89-104.
19. Nichols R., McCormick J. and Lim I. (1999b) Regulation of Drosophila FMRFamide neuropeptide gene expression. J. Neurobiol. 39, 347-358.
20. Nielsen H., Engelbrecht J., Brunak S. and von Heijne G. (1947) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6.
21. Orchard I., Lange A. B. and Bendena W. G. (2001) FMRFamide-related peptides: a multifunctional family of structurally related neuropeptides in insects. Adv. Insect Physiol. 28, 267-329.
22. Perkins D. N., Pappin D. J., Creasy D. M. and Cottrell J. S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 20, 3551-3567.
23. Riehle M. A., Garczynski S. F., Crim J. W., Hill C. A. and Brown M. R. (2002) Neuropeptides and peptide hormones in Anopheles gambiae. Science 298, 172-175.
24. 2 (FMRFamide). Proc. Natl Acad. Sci. USA 85, 1993-1997.
25. Taghert P. H. (1999) FMRFamide neuropeptides and neuropeptide-associated enzymes in Drosophila. Microsc. Res. Tech. 45, 80-95.
26. Vanden Broeck J. (2001) Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster. Peptides 22, 241-254.
27. Veenstra J. A. (2000) Mono- and dibasic proteolytic cleavage sites in insect neuroendocrine peptide precursors. Arch. Insect Biochem. Physiol. 43, 49-60.
28. White K., Hurteau T. and Punsal P. (1986) Neuropeptide-FMRFamide-like immunoreactivity in Drosophila: development and distribution. J. Comp. Neurol. 247, 430-438.