Identification of a family of endocytic proteins that define a new α-adaptin ear-binding motif

EMBO Reports

Volumn 4, Issue 11, 2003, Pages 1089-1093

  Ritter, Brigitte ^a   Philie, Jacynthe ^a   Girard, Martine ^a   Tung, Elaine C ^a   Blondeau, Francois ^a   McPherson, Peter S ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIN EAR BINDING COAT ASSOCIATED PROTEIN; ADAPTOR PROTEIN; CARRIER PROTEIN; ISOPROTEIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; COATED VESICLE; CONTROLLED STUDY; ENDOCYTOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PARALOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; PROTEOMICS; RAT; SEQUENCE HOMOLOGY;

ANIMALIA;

EID: 0345814988     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400004     Document Type: Article

References (18)

1. Brett, T.J., Traub, L.M. & Fremont, D.H. (2002) Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure, 10, 797-809.
2. Brodin, L., Low, P. & Shupliakov, O. (2000) Sequential steps in clathrin-mediated synaptic vesicle endocytosis. Curr. Opin. Neurobiol., 10, 312-320.
3. Conner, S.D. & Schmid, S.L. (2003) Regulated portals of entry into the cell. Nature, 422, 37-44.
4. Hussain, N.K. et al. (1999) Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells. J. Biol. Chem., 274, 15671-15677.
5. Legendre-Guillemin, V. et al. (2002). HIP1 and HIP12 display differential binding to F-actin, AP-2, and clathrin. Identification of a novel interaction with clathrin light chain. J. Biol, Chem., 277, 19897-19904.
6. McPherson, P.S., Takei, K., Schmid, S.L. & De Camilli, P. (1994) p145, a major Grb2-binding protein in brain, is co-localized with dynamin in nerve terminals where it undergoes activity-dependent dephosphorylation. J. Biol. Chem., 269, 30132-30139.
7. McPherson, P.S. (2002) The endocytic machinery at an interface with the actin cytoskeleton: a dynamic, hip intersection. Trends Cell Biol., 12, 312-315.
8. Metzler, M. et al. (2001) HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2. J. Biol. Chem., 276, 39271-39276.
9. Mishra, S.K. et al. (2002) Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor. EMBO J., 21, 4915-4926.
10. Owen, D.J. et al. (1999) A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain. Cell, 97, 805-815.
11. Owen, D.J., Vallis, Y., Pearse, B.M., McMahon, H.T. & Evans, P.R. (2000) The structure and function of the β2-adaptin appendage domain. EMBO J., 19, 4216-4227.
12. Ramjaun, A.R., Micheva, K.D., Bouchelet, I. & McPherson, P.S. (1997) Identification and characterization of a nerve terminal-enriched amphiphysin isoform. J. Biol. Chem., 272, 16700-16706.
13. Robinson, M.S. & Bonifacino, J.S. (2001) Adaptor-related proteins. Curr. Opin. Cell Biol., 13, 444-453.
14. Rosenthal, J.A. et al. (1999) The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module. J. Biol. Chem., 274, 33959-33965.
15. Slepnev, V.I. & De Camilli, P. (2000) Accessory factors in clathrin-dependent synaptic vesicle endocytosis. Nature Rev. Neurosci., 1, 161-172.
16. Takei, K., McPherson, P.S., Schmid, S.L. & De Camilli, P. (1995) Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals. Nature, 374, 186-190.
17. Traub, L.M., Downs, M.A., Westrich, J.L. & Fremont, D.H. (1999) Crystal structure of the α appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Proc. Natl Acad. Sci. USA, 96, 8907-8912.
18. Wasiak, S. et al. (2002). Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. J. Cell Biol., 158, 855-862.