Contribution of the respiratory rhythm to sinus arrhythmia in normal unanesthetized subjects during positive-pres sure mechanical hyperventilation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 286, Issue 1 55-1, 2004, Pages

  Cooper, H E ^a   Clutton Brock, T H ^a   Parkes, M J ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Eupnea; Hypocaphia

Indexed keywords

CARBON DIOXIDE;

ADULT; AIRWAY PRESSURE; ARTICLE; BREATHING PATTERN; ELECTROMYOGRAM; HEART CYCLE; HUMAN; HUMAN EXPERIMENT; HYPERVENTILATION; HYPOCAPNIA; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; SINUS ARRHYTHMIA; STATISTICAL ANALYSIS; SYSTOLIC BLOOD PRESSURE; TIDAL VOLUME;

EID: 0345737067     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00504.2003     Document Type: Article

References (72)

1. Abel FL and Waldhausen JA. Respiratory and cardiac effects on venous return. Am Heart J 78: 266-275, 1969.
2. AI-Ani M, Forkins AS, Townend JN, and Coote JH. Respiratory sinus arrhythmia and central respiratory drive in humans. Clin Sci (Lond) 90: 235-241, 1996.
3. Altose MD, Castele RJ, Connors AF, and Dimarco AF. Effects of volume and frequency of mechanical ventilation on respiratory activity in humans. Respir Physiol 66: 171-180, 1986.
4. American Physiological Society. Guiding principles for research involving animals and human beings. Am J Physiol Regul Integr Comp Physiol 283: R283, 2002.
5. Angelone A and Coulter NA. Respiratory sinus arrhythmia: a frequency-dependent phenomenon. J Appl Physiol 19: 479-482, 1964.
6. Anrep GV, Pascual W, and Rossler R. Respiratory variations of the heart rate. 1. The reflex mechanism of the respiratory sinus arrhythmia. Proc R Soc Lond Ser B 119: 191-217, 1936.
7. Anrep GV, Pascual W, and Rossler R. Respiratory variations of the heart rate. 2. The central mechanism of the respiratory arrhythmia and the interactions between the central and the reflex mechanisms. Proc R Soc Lond Ser B 119: 218-230, 1936.
8. Bainbridge FA. The influence of venous filling upon the rate of the heart. J Physiol 50: 65-84, 1915.
9. Bainton CR and Mitchell RA. Posthyperventilation apnea in awake man. J Appl Physiol 21: 411-415, 1966.
10. 2 and results of vagal cooling. Respir Physiol 34: 121-134, 1978.
11. 2 in the anesthetized rat: fundamental properties under steady-state conditions. J Appl Physiol 85: 898-907, 1998.
12. Brown TE, Beightol LA, Koh J, and Eckberg DL. Important influence of respiration on human R-R interval power spectra is largely ignored. J Appl Physiol 75: 2310-2317, 1993.
13. Cohen MA and Taylor AJ. Short-term cardiovascular oscillations in man: measuring and modelling the physiologies. J Physiol 542: 669-683, 2002.
14. 2, lung receptors, and central inspiratory activity. J Appl Physiol 60: 1713-1721, 1986.
15. 2-dependent components of sinus arrhythmia from the start of breath-holding in man. Am J Physiol Heart Circ Physiol 285: H841-H848, 2003.
16. Corfield DR, Morrell MJ, and Guz A. The nature of breathing during hypocapnia in awake man. Respir Physiol 101: 145-159, 1995.
17. Cullen DJ, Eger EI, and Gregory GA. The cardiovascular effects of carbon dioxide in man, conscious and during cyclopropane anesthesia. Anesthesiology 31: 407-413, 1969.
18. 2 and in arterial pH. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, p. 475-528.
19. Daly MD. Interactions between respiration and circulation. In: Handbook of Physiology, The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, p. 529-594.
20. Datta AK, Shea SA, Horner RL, and Guz A. The influence of induced hypocapnia and sleep on the endogenous respiratory rhythm in humans. J Physiol 440: 17-33, 1991.
21. Eckberg DL. Human sinus arrhythmia as an index of vagal cardiac outflow. J Appl Physiol 54: 961-966, 1983.
22. Eckberg DL, Kifle YT, and Roberts VL. Phase relationship between normal human respiration and baroreflex responsiveness. J Physiol 304: 489-502, 1980.
23. Eckberg DL and Orshan CR. Respiratory and baroreceptor reflex interactions in man. J Clin Invest 59: 780-785, 1977.
24. Eckberg DL and Sleight P. Human Baroreflexes in Health and Disease. Oxford, UK: Clarendon, 1992.
25. Freyschuss U and Melcher A. Sinus arrhythmia in man: influence of tidal volume and oesophageal pressure. Scand J Clin Lab Invest 35: 487-496, 1975.
26. Giardino ND, Glenny RW, Borson S, and Chan L. Respiratory sinus arrhythmia is associated with efficiency of pulmonary gas exchange in healthy humans. Am J Physiol Heart Circ Physiol 284: H1585-H1591, 2003.
27. Gilbey MP, Jordan D, Richter DW, and Spyer KM. Synaptic mechanisms involved in the inspiratory modulation of vagal cardio-inhibitory neurones in the cat. J Physiol 356: 65-78, 1984.
28. Guz A, Innes JA, and Murphy K. Respiratory modulation of left ventricular stroke volume in man measured using pulsed Doppler ultrasound. J Physiol 393: 499-512, 1987.
29. Hayano J, Mukai S, Sakakibara M, Okada A, Takata K, and Fujinami T. Effects of respiratory interval on vagal modulation of heart rate. Am J Physiol Heart Circ Physiol 267: H33-H40, 1994.
30. Henke KG, Arias A, Skatrud JB, and Dempsey JA. Inhibition of inspiratory muscle activity during sleep. Am Rev Respir Dis 138: 8-15, 1988.
31. Hirsch JA and Bishop B. Respiratory sinus arrhythmia in humans: how breathing pattern modulates heart rate. Am J Physiol Heart Circ Physiol 241: H620-H629, 1981.
32. Iber C, Simon PM, Skatrud JB, Mahowald MW, and Dempsey JA. The Breuer-Hering reflex in humans. Effects of pulmonary denervation and hypocapnia. Am J Respir Crit Care Med 152: 217-224, 1995.
33. Imholz BP, Van Montfrans GA, Settels JJ, van der Hoeven GM, Karemaker JM, and Wieling W. Continuous non-invasive blood pressure monitoring: reliability of Finapres device during the Valsalva manoeuvre. Cardiovasc Res 22: 390-397, 1988.
34. 2 responsiveness. Am J Respir Dis 144: 1125-1129, 1991.
35. Innes JA, De Cort SC, Kox W, and Guz A. Within-breath modulation of left ventricular function during normal breathing and positive-pressure ventilation in man. J Physiol 460: 487-502, 1993.
36. Joy M and Trump DW. Significance of minor ST segment and T wave changes in the resting electrocardiogram of asymptomatic subjects. Br Heart J 45: 48-55, 1981.
37. Kety SS and Schmidt CF. The effects of active and passive hyperventilation on cerebral blood flow, cerebral oxygen consumption, cardiac output and blood pressure in normal young men. J Clin Invest 25: 107-119, 1946.
38. Kollai M and Mizsei G. Respiratory sinus arrhythmia is a limited measure of cardiac parasympathetic control in man. J Physiol 424: 329-342, 1990.
39. Lansing R and Savelle J. Chest surface recording of diaphragm potentials in man. Electroencephalogr Clin Neurophysiol 72: 59-68, 1989.
40. Leevers AM, Simon PM, Xi L, and Dempsey JA. Apnoea following normocapnic mechanical ventilation in awake mammals: a demonstration of control system inertia. J Physiol 472: 749-768, 1993.
41. Lofaso F, Isabey D, Lorino H, Harf A, and Scheid P. Respiratory response to positive and negative inspiratory pressure in humans. Respir Physiol 89: 75-88, 1992.
42. Macefield VG and Burke D. Paraesthesiae and tetany induced by voluntary hyperventilation. Brain 114: 527-540, 1991.
43. Manchanda S, Leevers AM, Wilson CR, Simon PM, Skatrud JB, and Dempsey JA. Frequency and volume thresholds for inhibition of inspiratory motor output during mechanical ventilation. Respir Physiol 105: 1-16, 1996.
44. McGregor M, Donovan RE, and Anderson NM. Influence of carbon dioxide and hyperventilation on cardiac output in man. J Appl Physiol 17: 933-937, 1962.
45. Meah MS and Gardner WN. Post-hyperventilation apnoea in conscious humans. J Physiol 477: 527-538, 1994.
46. Melcher A. Carotid baroreflex heart rate control during the active and the assisted breathing cycle in man. Acta Physiol Scand 108: 165-171, 1980.
47. 2 and airway pressure on phrenic activity and pulmonary stretch receptor discharge in dogs. Respir Physiol 41: 29-48, 1980.
48. Morrell MJ, Shea SA, Adams L, and Guz A. Effects of inspiratory support upon breathing in humans during wakefulness and sleep. Respir Physiol 93: 57-70, 1993.
49. Novak V, Novak P, de Champlain J, Le Blanc AR, Martin R, and Nadeau R. Influence of respiration on heart rate and blood pressure fluctuations. J Appl Physiol 74: 617-626, 1993.
50. Novak V, Saul JP, and Eckberg DL. Task Force report on heart rate variability. Circulation 96: 1056-1057, 1997.
51. Parati G, Casadei R, Groppelli A, Di Rienzo M, and Mancia G. Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension 13: 647-655, 1989,
52. Perneger TV. What's wrong with the Bonferroni adjustments. Br Med J 316: 236-238, 1998.
53. Pinsky MR. The effects of mechanical ventilation on the cardiovascular system. Crit Care Clin 6: 663-677, 1990.
54. Prechter GC, Nelson SB, and Hubmayr RD. The ventilatory recruitment threshold for carbon dioxide. Am Rev Respir Dis 141: 758-764, 1990.
55. Richardson DW, Kontos HA, Raper AJ, and Patterson JL Jr. Systemic circulatory responses to hypocapnia in man. Am J Physiol 223: 1308-1312, 1972.
56. CO2 in men. J Appl Physiol 68: 1727-1731, 1990.
57. CO2 on respiratory sinus arrhythmia in conscious humans. Am J Physiol Heart Circ Physiol 282: H973-H976, 2002.
58. Saul JP, Berger RD, Chen MH, and Cohen RJ. Transfer function analysis of autonomic regulation. II. Respiratory sinus arrhythmia. Am J Physiol Heart Circ Physiol 256: H153-H161, 1989.
59. Sears TA and Seers CP. The central expiratory drive to vagal cardiac preganglionic neurones in the anaesthetised cat (Abstract). J Physiol 505: 22P, 1997.
60. Selman A, McDonald A, Kitney RI, and Linkens D. The interaction between heart rate and respiration. I. Experimental studies in man. Automedica 4: 131-139, 1982.
61. Shea SA. Behavioural and arousal-related influences on breathing in humans. Exp Physiol 81: 1-26, 1996.
62. Simon PM, Dempsey JA, Landry DM, and Skatrud JB. Effect of sleep on respiratory muscle activity during mechanical ventilation. Effect of sleep on respiratory muscle activity during mechanical ventilation. Am Rev Respir Dis 147: 32-37, 1993.
63. Simon PM, Griffin DM, Landry DM, and Skatrud JB. Inhibition of respiratory activity during passive ventilation: a role for intercostal afferents? Respir Physiol 92: 53-64, 1993.
64. Taha BH, Simon PM, Dempsey JA, Skatrud JB, and Iber C. Respiratory sinus arrhythmia in humans: an obligatory role for vagal feedback from the lungs. J Appl Physiol 78: 638-645, 1995.
65. Task Force. Heart rate variability, standards of measurement, physiological interpretation and clinical use. Circulation 93: 1043-1065, 1996.
66. Taylor EW, Jordan D, and Coote JH. Central control of the cardiovascular and respiratory systems and their interactions in vertebrates. Physiol Rev 79: 855-916, 1999.
67. Taylor JA, Myers CW, Halliwill JR, Seidel H, and Eckberg DL. Sympathetic restraint of respiratory sinus arrhythmia: implications for vagal-cardiac tone assessment in humans. Am J Physiol Heart Circ Physiol 280: H2804-H2814, 2001.
68. Van de Borne P, Mezzetti S, Montano N, Narkiewicz K, Degaute JP, and Somers VK. Hyperventilation alters arterial baroreflex control of heart rate and muscle sympathetic nerve activity. Am J Physiol Heart Circ Physiol 279: H536-H541, 2000.
69. Van den Berg PC, Jansen JR, and Pinsky MR. Effect of positive pressure on venous return in volume-loaded cardiac surgical patients. J Appl Physiol 92: 1223-1231, 2002.
70. O2 and leg blood flow during submaximal exercise. J Appl Physiol 87: 643-651, 1999.
71. Wilson CR, Satoh M, Skatrud JB, and Dempsey JA. Non-chemical inhibition of respiratory motor output during mechanical ventilation in sleeping humans. J Physiol 518: 605-618, 1999.
72. Yli-Hankala A, Porkkala T, Kaukinen S, Hakkinen V, and Jantt V. Respiratory sinus arrhythmia is reversed during positive-pressure ventilation. Acta Physiol Scand 141: 399-407, 1991.