Degradable poly(amino alcohol esters) as potential DNA vectors with low cytotoxicity

Biomacromolecules

Volumn 4, Issue 6, 2003, Pages 1759-1762

  Jon, Sangyong ^a   Anderson, Daniel G ^a   Langer, Robert ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPHILIC ADDITION; POLYMER COMPLEXES;

DEGRADATION; DNA; GENES; HYDROLYSIS; MONOMERS; SYNTHESIS (CHEMICAL); TOXICITY;

POLYESTERS;

1,3 PROPANEDIAMINE; 1,6 HEXANEDIAMINE; ADIPIC ACID; AMINE; BIOPOLYMER; BUFFER; DICARBOXYLIC ACID; DNA; ESTER DERIVATIVE; MONOMER; PHOSPHATE; PLASMID DNA; POLY(AMINOALCOHOL ESTER); POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY TEST; DEGRADATION; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HALF LIFE TIME; HYDROLYSIS; MOLECULAR SIZE; MOUSE; NONHUMAN; PH MEASUREMENT; POLYMERIZATION; PRIORITY JOURNAL; SYNTHESIS;

3T3 CELLS; AMINO ALCOHOLS; ANIMALS; BIODEGRADATION, ENVIRONMENTAL; CELL SURVIVAL; DNA; GENE THERAPY; MATERIALS TESTING; MICE; PARTICLE SIZE; PLASMIDS; POLYESTERS; SOLUBILITY; TRANSFECTION;

ANIMALIA;

EID: 0345688743     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm034176f     Document Type: Article

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