메뉴 건너뛰기




Volumn 103, Issue 1, 1999, Pages 1-14

Insertional tagging of at least two loci associated with resistance to adenine arabinoside in Toxoplasma gondii, and cloning of the adenosine kinase locus

Author keywords

Adenosine kinase; Adenosine transport; Gene targeting; Insertional mutagenesis; Knock out mutants; Molecular parasitology; Purine metabolism

Indexed keywords

ADENOSINE KINASE; VIDARABINE;

EID: 0345672739     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(99)00114-0     Document Type: Article
Times cited : (58)

References (40)
  • 4
    • 0015101204 scopus 로고
    • Incorporation of precursors into Toxoplasma DNA
    • Perotto J., Keister D.B., Gelderman A.H. Incorporation of precursors into Toxoplasma DNA. J. Protozool. 18:1971;470-473.
    • (1971) J. Protozool. , vol.18 , pp. 470-473
    • Perotto, J.1    Keister, D.B.2    Gelderman, A.H.3
  • 5
    • 0020026153 scopus 로고
    • Toxoplasma gondii: Purine synthesis and salvage in mutant host cells and parasites
    • Schwartzman J.D., Pfefferkorn E.R. Toxoplasma gondii: purine synthesis and salvage in mutant host cells and parasites. Exp. Parasitol. 53:1982;77-86.
    • (1982) Exp. Parasitol. , vol.53 , pp. 77-86
    • Schwartzman, J.D.1    Pfefferkorn, E.R.2
  • 6
    • 0024340636 scopus 로고
    • Purine metabolism in Toxoplasma gondii
    • Krug E.C., Marr J.J., Berens R.L. Purine metabolism in Toxoplasma gondii. J. Biol. Chem. 264:1989;10601-10607.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10601-10607
    • Krug, E.C.1    Marr, J.J.2    Berens, R.L.3
  • 7
    • 0017865319 scopus 로고
    • The biochemical basis for resistance to adenine arabinoside in a mutant of Toxoplasma gondii
    • Pfefferkorn E.R., Pfefferkorn L.C. The biochemical basis for resistance to adenine arabinoside in a mutant of Toxoplasma gondii. J. Parasitol. 64:1978;486-492.
    • (1978) J. Parasitol. , vol.64 , pp. 486-492
    • Pfefferkorn, E.R.1    Pfefferkorn, L.C.2
  • 9
    • 0029066380 scopus 로고
    • Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii
    • Iltzsch M.H., Uber S.S., Ankersley K.O., el Kouni M.H. Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii. Biochem. Pharm. 49:1995;1501-1512.
    • (1995) Biochem. Pharm. , vol.49 , pp. 1501-1512
    • Iltzsch, M.H.1    Uber, S.S.2    Ankersley, K.O.3    El Kouni, M.H.4
  • 10
    • 84880917438 scopus 로고    scopus 로고
    • Metabolism and selective toxicity of 6-nitrobenzylthioinosine in Toxoplasma gondii
    • el Kouni M.H., Guarcello V., Al Safarjalani O.N., Naguib F.N.M. Metabolism and selective toxicity of 6-nitrobenzylthioinosine in Toxoplasma gondii. FASEB J. 12:1998;A126.
    • (1998) FASEB J. , vol.12 , pp. 126
    • El Kouni, M.H.1    Guarcello, V.2    Al Safarjalani, O.N.3    Naguib, F.N.M.4
  • 12
    • 0029907188 scopus 로고    scopus 로고
    • Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species: High frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene
    • Singh B., Hao W., Wu Z., Eigl B., Gupta R.S. Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species: high frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene. Eur. J. Biochem. 241:1996;564-571.
    • (1996) Eur. J. Biochem. , vol.241 , pp. 564-571
    • Singh, B.1    Hao, W.2    Wu, Z.3    Eigl, B.4    Gupta, R.S.5
  • 14
    • 0028709114 scopus 로고
    • Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii
    • Roos D.S., Donald R.G.K., Morrissette N.S., Moulton A.L.C. Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii. Methods Cell Biol. 45:1994;23-65.
    • (1994) Methods Cell Biol. , vol.45 , pp. 23-65
    • Roos, D.S.1    Donald, R.G.K.2    Morrissette, N.S.3    Moulton, A.L.C.4
  • 16
    • 0021681568 scopus 로고
    • New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition
    • Way J.C., Davis M.A., Morisato D., Roberts D.E., Kleckner N. New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition. Gene. 32:1984;369-379.
    • (1984) Gene , vol.32 , pp. 369-379
    • Way, J.C.1    Davis, M.A.2    Morisato, D.3    Roberts, D.E.4    Kleckner, N.5
  • 17
    • 0029050555 scopus 로고
    • Insertional mutagenesis in a protozoan parasite: Direct cloning of the uracil phosphoribosyltransferase gene from Toxoplasma gondii
    • Donald R.G.K., Roos D.S. Insertional mutagenesis in a protozoan parasite: direct cloning of the uracil phosphoribosyltransferase gene from Toxoplasma gondii. Proc. Natl. Acad. Sci. USA. 92:1995;5749-5753.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5749-5753
    • Donald, R.G.K.1    Roos, D.S.2
  • 18
    • 0029895115 scopus 로고    scopus 로고
    • Insertional tagging, cloning and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene: Characterization of a new genetic marker for stable transformation
    • Donald R.G.K., Carter D., Ullman B., Roos D.S. Insertional tagging, cloning and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene: characterization of a new genetic marker for stable transformation. J. Biol. Chem. 271:1996;14010-14019.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14010-14019
    • Donald, R.G.K.1    Carter, D.2    Ullman, B.3    Roos, D.S.4
  • 19
    • 0031255827 scopus 로고    scopus 로고
    • Tagging genes and trapping promoters in Toxoplasma gondii by insertional mutagenesis
    • Roos D.S., Sullivan W.J. Jr., Striepen B., Bohne W., Donald R.G.K. Tagging genes and trapping promoters in Toxoplasma gondii by insertional mutagenesis. Methods. 13:1997;112-122.
    • (1997) Methods , vol.13 , pp. 112-122
    • Roos, D.S.1    Sullivan W.J., Jr.2    Striepen, B.3    Bohne, W.4    Donald, R.G.K.5
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 24
    • 0015944892 scopus 로고
    • Enzyme inhibitors 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines
    • Schaeffer H.J., Schwender C.F. Enzyme inhibitors 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines. J. Med. Chem. 17:1974;6-8.
    • (1974) J. Med. Chem. , vol.17 , pp. 6-8
    • Schaeffer, H.J.1    Schwender, C.F.2
  • 25
    • 0017029795 scopus 로고
    • Arabinosyl nucleosides inhibit Toxoplasma gondii and allow the selection of resistant mutants
    • Pfefferkorn E.R., Pfefferkorn L.C. Arabinosyl nucleosides inhibit Toxoplasma gondii and allow the selection of resistant mutants. J. Parasitol. 62:1976;993-999.
    • (1976) J. Parasitol. , vol.62 , pp. 993-999
    • Pfefferkorn, E.R.1    Pfefferkorn, L.C.2
  • 27
    • 0030889496 scopus 로고    scopus 로고
    • Consensus sequence of translational initiation sites from Toxoplasma gondii genes
    • Seeber F. Consensus sequence of translational initiation sites from Toxoplasma gondii genes. Parasitol. Res. 83:1997;309-311.
    • (1997) Parasitol. Res. , vol.83 , pp. 309-311
    • Seeber, F.1
  • 28
    • 0027154749 scopus 로고
    • Analysis of dinucleotide frequency and codon usage in the phylum Apicomplexa
    • Ellis J., Griffin H., Morrison D., Johnson A.M. Analysis of dinucleotide frequency and codon usage in the phylum Apicomplexa. Gene. 126:1993;163-170.
    • (1993) Gene , vol.126 , pp. 163-170
    • Ellis, J.1    Griffin, H.2    Morrison, D.3    Johnson, A.M.4
  • 29
    • 0027479899 scopus 로고
    • Primary structure of the dihydrofolate reductase/thymidylate synthase gene from Toxoplasma gondii
    • Roos D.S. Primary structure of the dihydrofolate reductase/thymidylate synthase gene from Toxoplasma gondii. J. Biol. Chem. 268:1993;6269-6280.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6269-6280
    • Roos, D.S.1
  • 30
    • 0032521445 scopus 로고    scopus 로고
    • Gene knock-outs and allelic replacements in Toxoplasma gondii: HXGPRT as a selectable marker for 'hit-and-run' mutagenesis
    • Donald R.G.K., Roos D.S. Gene knock-outs and allelic replacements in Toxoplasma gondii: HXGPRT as a selectable marker for 'hit-and-run' mutagenesis. Mol. Biochem. Parasitol. 91:1998;295-305.
    • (1998) Mol. Biochem. Parasitol. , vol.91 , pp. 295-305
    • Donald, R.G.K.1    Roos, D.S.2
  • 31
    • 0028211397 scopus 로고
    • Homologous recombination and gene replacement at the dihydrofolate reductase/thymidylate synthase locus in Toxoplasma gondii
    • Donald R.G.K., Roos D.S. Homologous recombination and gene replacement at the dihydrofolate reductase/thymidylate synthase locus in Toxoplasma gondii. Mol. Biochem. Parasitol. 64:1994;243-253.
    • (1994) Mol. Biochem. Parasitol. , vol.64 , pp. 243-253
    • Donald, R.G.K.1    Roos, D.S.2
  • 32
    • 0024041593 scopus 로고
    • Molecular Koch's postulates applied to microbial pathogenicity
    • Falkow S. Molecular Koch's postulates applied to microbial pathogenicity. Rev. Infect. Dis. 10(Suppl. 2):1988;S274-276.
    • (1988) Rev. Infect. Dis. , vol.10 , Issue.SUPPL. 2 , pp. 274-276
    • Falkow, S.1
  • 33
    • 0028836011 scopus 로고
    • Hypoxanthine-guanine phosphoribosyltransferase as a therapeutic target in protozoal infections
    • Ullman B., Carter D. Hypoxanthine-guanine phosphoribosyltransferase as a therapeutic target in protozoal infections. Infect. Agents Dis. 4:1995;29-40.
    • (1995) Infect. Agents Dis. , vol.4 , pp. 29-40
    • Ullman, B.1    Carter, D.2
  • 34
    • 0028826429 scopus 로고
    • Structure-activity relationship for the binding of ligands to guanine or xanthine phosphoribosyltransferases from Toxoplasma gondii
    • Naguib F.N.M., Iltzsch M.H., el Kouni M.M, Panzica R.P., el Kouni M.H. Structure-activity relationship for the binding of ligands to guanine or xanthine phosphoribosyltransferases from Toxoplasma gondii. Biochem. Pharmacol. 50:1995;1685-1693.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1685-1693
    • Naguib, F.N.M.1    Iltzsch, M.H.2    El Kouni, M.M.3    Panzica, R.P.4    El Kouni, M.H.5
  • 35
    • 0025108051 scopus 로고
    • Therapeutic efficacy of allopurinol in patients with chronic Chagas' disease
    • Gallerano R.H., Sosa R.R., Marr J.J. Therapeutic efficacy of allopurinol in patients with chronic Chagas' disease. Am. J. Trop. Med. Hyg. 43:1990;159-166.
    • (1990) Am. J. Trop. Med. Hyg. , vol.43 , pp. 159-166
    • Gallerano, R.H.1    Sosa, R.R.2    Marr, J.J.3
  • 36
    • 0026541511 scopus 로고
    • Allopurinol in the treatment of American cutaneous leishmaniasis
    • Martinez S., Marr J.J. Allopurinol in the treatment of American cutaneous leishmaniasis. N. Engl. J. Med. 326:1992;741-744.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 741-744
    • Martinez, S.1    Marr, J.J.2
  • 37
    • 0029742013 scopus 로고    scopus 로고
    • Crystal structures of Toxoplasma gondii HXGPRTase reveal the catalytic role of a long flexible loop
    • Schumacher M.A., Carter D., Roos D.S., Ullman B., Brennan R.G. Crystal structures of Toxoplasma gondii HXGPRTase reveal the catalytic role of a long flexible loop. Nat. Struct. Biol. 3:1996;881-887.
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 881-887
    • Schumacher, M.A.1    Carter, D.2    Roos, D.S.3    Ullman, B.4    Brennan, R.G.5
  • 38
    • 0026100921 scopus 로고
    • A workbench for multiple alignment construction and analysis
    • Schuler G.D., Altschul S.F., Lipman D.J. A workbench for multiple alignment construction and analysis. Proteins. 9:1991;180-190.
    • (1991) Proteins , vol.9 , pp. 180-190
    • Schuler, G.D.1    Altschul, S.F.2    Lipman, D.J.3
  • 39
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:1994;4673-4680.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 40
    • 0032868347 scopus 로고    scopus 로고
    • Recombinant expression, purification and characterization of Toxoplasma gondii adenosine kinase
    • Darling JA, Sullivan WJJr, Carter D, Ullman B, Roos DS. Recombinant expression, purification and characterization of Toxoplasma gondii adenosine kinase. Mol Biochem Parasitol 1999;103:15-23.
    • (1999) Mol Biochem Parasitol , vol.103 , pp. 15-23
    • Darling, J.A.1    Sullivan W.J., Jr.2    Carter, D.3    Ullman, B.4    Roos, D.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.